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GO:0004087 carbamoyl-phosphate synthase (ammonia) activity

Term Information

ID GO:0004087
Name carbamoyl-phosphate synthase (ammonia) activity
Ontology Molecular Function
Definition Catalysis of the reaction: 2 ATP + CO(2) + H(2)O + NH(4)(+) = 2 ADP + carbamoyl phosphate + 5 H(+) + phosphate.
GONUTS GO:0004087 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact carbamoyl phosphate synthase (ammonia) activity
related carbamylphosphate synthetase I
exact carbmoylphosphate synthetase activity
exact carbamylphosphate synthetase activity
exact carbon-dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating)
exact carbamoylphosphate synthase (ammonia)
exact carbon-dioxide--ammonia ligase activity
exact carbamoylphosphate synthetase (ammonia) activity
exact carbamoyl-phosphate synthetase I activity
exact carbamoyl-phosphate synthetase (ammonia) activity
narrow CPS I activity
exact carbamoylphosphate synthase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 6.3.4.16
KEGG R00149
MetaCyc 6.3.4.16-RXN
RHEA 10627

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0004086 carbamoyl-phosphate synthase activity CONSIDER GO:0004087

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004087:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004087. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004087 based on the entire annotation set Co-occurrence statistics for GO:0004087 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-09-04 Added RELATION is a GO:0016879 (ligase activity, forming carbon-nitrogen bonds)
2011-09-04 Deleted RELATION is a GO:0004086 (carbamoyl-phosphate synthase activity)
2010-10-11 Deleted DEFINITION Catalysis of the reaction: 2 ATP + NH3 + CO2 + H2O = 2 ADP + phosphate + carbamoyl phosphate.
2010-10-11 Added DEFINITION Catalysis of the reaction: 2 ATP + CO(2) + H(2)O + NH(4)(+) = 2 ADP + carbamoyl phosphate + 5 H(+) + phosphate.
2010-10-11 Added XREF RHEA:10627
2010-10-11 Added XREF KEGG:R00149
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 ATP + NH3 + CO2 + H2O = 2 ADP + phosphate + carbamoyl phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 ATP + NH3 + CO2 + H2O = 2 ADP + phosphate + carbamoyl phosphate.
2008-04-01 Updated RELATION is a GO:0004086 (carbamoyl-phosphate synthase activity)
2007-11-08 Added SYNONYM carbamoylphosphate synthase (ammonia)
2007-11-08 Added SYNONYM carbamoylphosphate synthase activity
2007-11-08 Added SYNONYM carbamylphosphate synthetase I
2007-11-08 Added SYNONYM carbamylphosphate synthetase activity
2007-11-08 Added SYNONYM carbmoylphosphate synthetase activity
2007-11-08 Added SYNONYM carbon-dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating)
2007-09-06 Added SYNONYM CPS I activity
2007-09-06 Added SYNONYM carbamoyl-phosphate synthetase (ammonia) activity
2007-09-06 Added SYNONYM carbamoyl-phosphate synthetase I activity
2007-09-06 Added SYNONYM carbamoylphosphate synthetase (ammonia) activity
2007-09-06 Added SYNONYM carbon-dioxide--ammonia ligase activity
2007-08-09 Deleted SYNONYM carbamoyl phosphate synthase (ammonia) activity
2007-08-09 Added SYNONYM carbamoyl phosphate synthase (ammonia) activity
2007-05-06 Added SYNONYM carbamoyl phosphate synthase (ammonia) activity
2003-10-30 Updated DEFINITION Catalysis of the reaction: 2 ATP + NH3 + CO2 + H2O = 2 ADP + phosphate + carbamoyl phosphate.
2003-10-27 Added XREF MetaCyc:6.3.4.16-RXN
2003-10-23 Updated DEFINITION Catalysis of the reaction: 2 ATP + ammonia + CO2 + H2O = 2 ADP + phosphate + carbamoyl phosphate.
2003-03-19 Updated TERM carbamoyl-phosphate synthase (ammonia) activity
2002-11-27 Added DEFINITION Catalysis of the reaction: 2 ATP + ammonia + carbon dioxide + H2O = 2 ADP + phosphate + carbamoyl phosphate.
2002-02-06 Updated TERM carbamoyl-phosphate synthase (ammonia)
2001-04-03 Updated TERM carbamoyl-phosphate synthase (ammonia)
2001-03-30 Added XREF EC:6.3.4.16
2001-03-30 Added TERM carbamoyl-phosphate synthase (ammonia)

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM carbamoyl-phosphate synthase (ammonia) activity
2002-02-06 Updated TERM carbamoyl-phosphate synthase (ammonia)
2001-04-03 Updated TERM carbamoyl-phosphate synthase (ammonia)
2001-03-30 Added TERM carbamoyl-phosphate synthase (ammonia)

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: 2 ATP + NH3 + CO2 + H2O = 2 ADP + phosphate + carbamoyl phosphate.
2010-10-11 Added DEFINITION Catalysis of the reaction: 2 ATP + CO(2) + H(2)O + NH(4)(+) = 2 ADP + carbamoyl phosphate + 5 H(+) + phosphate.
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 ATP + NH3 + CO2 + H2O = 2 ADP + phosphate + carbamoyl phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 ATP + NH3 + CO2 + H2O = 2 ADP + phosphate + carbamoyl phosphate.
2007-11-08 Added SYNONYM carbamoylphosphate synthase (ammonia)
2007-11-08 Added SYNONYM carbamoylphosphate synthase activity
2007-11-08 Added SYNONYM carbamylphosphate synthetase I
2007-11-08 Added SYNONYM carbamylphosphate synthetase activity
2007-11-08 Added SYNONYM carbmoylphosphate synthetase activity
2007-11-08 Added SYNONYM carbon-dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating)
2007-09-06 Added SYNONYM CPS I activity
2007-09-06 Added SYNONYM carbamoyl-phosphate synthetase (ammonia) activity
2007-09-06 Added SYNONYM carbamoyl-phosphate synthetase I activity
2007-09-06 Added SYNONYM carbamoylphosphate synthetase (ammonia) activity
2007-09-06 Added SYNONYM carbon-dioxide--ammonia ligase activity
2007-08-09 Deleted SYNONYM carbamoyl phosphate synthase (ammonia) activity
2007-08-09 Added SYNONYM carbamoyl phosphate synthase (ammonia) activity
2007-05-06 Added SYNONYM carbamoyl phosphate synthase (ammonia) activity
2003-10-30 Updated DEFINITION Catalysis of the reaction: 2 ATP + NH3 + CO2 + H2O = 2 ADP + phosphate + carbamoyl phosphate.
2003-10-23 Updated DEFINITION Catalysis of the reaction: 2 ATP + ammonia + CO2 + H2O = 2 ADP + phosphate + carbamoyl phosphate.
2002-11-27 Added DEFINITION Catalysis of the reaction: 2 ATP + ammonia + carbon dioxide + H2O = 2 ADP + phosphate + carbamoyl phosphate.

Relationships

Timestamp Action Category Detail
2011-09-04 Added RELATION is a GO:0016879 (ligase activity, forming carbon-nitrogen bonds)
2011-09-04 Deleted RELATION is a GO:0004086 (carbamoyl-phosphate synthase activity)
2008-04-01 Updated RELATION is a GO:0004086 (carbamoyl-phosphate synthase activity)

Cross-references

Timestamp Action Category Detail
2010-10-11 Added XREF RHEA:10627
2010-10-11 Added XREF KEGG:R00149
2003-10-27 Added XREF MetaCyc:6.3.4.16-RXN
2001-03-30 Added XREF EC:6.3.4.16
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