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GO:0004081 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity

Term Information

ID GO:0004081
Name bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
Ontology Molecular Function
Definition Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.
PMID:4955726
GONUTS GO:0004081 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact diadenosine P1,P4-tetraphosphatase activity
exact dinucleoside tetraphosphatase activity
exact 1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity
exact P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity
exact diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase activity
exact dinucleosidetetraphosphatase (asymmetrical) activity
narrow diguanosinetetraphosphatase (asymmetrical) activity
narrow diadenosinetetraphosphatase (asymmetrical) activity
exact diadenosine 5',5'''-P(1),P(4)-tetraphosphate asymmetrical hydrolase activity
narrow bis(5'-guanosyl)-tetraphosphatase activity
narrow bis(5'-adenosyl)-tetraphosphatase activity
broad Ap4Aase activity
broad Ap4A hydrolase activity
broad Ap(4)Aase activity
broad Ap(4)A hydrolase activity
narrow diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 3.6.1.17
InterPro IPR023937
MetaCyc 3.6.1.17-RXN
RHEA 22487

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004081:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004081. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004081 based on the entire annotation set Co-occurrence statistics for GO:0004081 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:22487
2008-05-13 Added DEFINITION Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.
2008-04-01 Updated RELATION is a GO:0008796 (bis(5'-nucleosyl)-tetraphosphatase activity)
2007-11-08 Added SYNONYM 1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity
2007-11-08 Added SYNONYM P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity
2007-11-08 Added SYNONYM diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase activity
2007-11-08 Added SYNONYM diadenosine P1,P4-tetraphosphatase activity
2007-11-08 Added SYNONYM dinucleoside tetraphosphatase activity
2007-09-06 Added SYNONYM Ap(4)A hydrolase activity
2007-09-06 Added SYNONYM Ap(4)Aase activity
2007-09-06 Added SYNONYM Ap4A hydrolase activity
2007-09-06 Added SYNONYM Ap4Aase activity
2007-09-06 Added SYNONYM bis(5'-adenosyl)-tetraphosphatase activity
2007-09-06 Added SYNONYM bis(5'-guanosyl)-tetraphosphatase activity
2007-09-06 Added SYNONYM diadenosine 5',5'''-P(1),P(4)-tetraphosphate asymmetrical hydrolase activity
2007-09-06 Added SYNONYM diadenosinetetraphosphatase (asymmetrical) activity
2007-09-06 Added SYNONYM diguanosinetetraphosphatase (asymmetrical) activity
2007-09-06 Added SYNONYM dinucleosidetetraphosphatase (asymmetrical) activity
2007-08-09 Added SYNONYM diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase
2007-08-09 Deleted SYNONYM diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase
2004-09-15 Updated DEFINITION Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.
2004-04-19 Added SYNONYM diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase
2004-04-16 Deleted SYNONYM diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase
2003-10-27 Added SYNONYM diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase
2003-10-27 Added XREF MetaCyc:3.6.1.17-RXN
2003-08-18 Deleted SYNONYM diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase
2003-03-19 Updated TERM bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
2002-11-27 Added DEFINITION Catalysis of the reaction: P(1),P(4)-bis(5'-guanosyl)tetraphosphate + H2O = GTP + GMP. Also acts on bis(5'-xanthosyl)-tetraphosphate and, more slowly, on bis(5'-adenosyl)-tetraphosphate and bis(5'-uridyl)-tetraphosphate.
2002-10-11 Added SYNONYM diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase
2002-02-06 Updated TERM bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
2001-04-03 Updated TERM bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
2001-03-30 Added XREF EC:3.6.1.17
2001-03-30 Added TERM bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
2002-02-06 Updated TERM bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
2001-04-03 Updated TERM bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
2001-03-30 Added TERM bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.
2007-11-08 Added SYNONYM 1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity
2007-11-08 Added SYNONYM P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity
2007-11-08 Added SYNONYM diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase activity
2007-11-08 Added SYNONYM diadenosine P1,P4-tetraphosphatase activity
2007-11-08 Added SYNONYM dinucleoside tetraphosphatase activity
2007-09-06 Added SYNONYM Ap(4)A hydrolase activity
2007-09-06 Added SYNONYM Ap(4)Aase activity
2007-09-06 Added SYNONYM Ap4A hydrolase activity
2007-09-06 Added SYNONYM Ap4Aase activity
2007-09-06 Added SYNONYM bis(5'-adenosyl)-tetraphosphatase activity
2007-09-06 Added SYNONYM bis(5'-guanosyl)-tetraphosphatase activity
2007-09-06 Added SYNONYM diadenosine 5',5'''-P(1),P(4)-tetraphosphate asymmetrical hydrolase activity
2007-09-06 Added SYNONYM diadenosinetetraphosphatase (asymmetrical) activity
2007-09-06 Added SYNONYM diguanosinetetraphosphatase (asymmetrical) activity
2007-09-06 Added SYNONYM dinucleosidetetraphosphatase (asymmetrical) activity
2007-08-09 Added SYNONYM diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase
2007-08-09 Deleted SYNONYM diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase
2004-09-15 Updated DEFINITION Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.
2004-04-19 Added SYNONYM diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase
2004-04-16 Deleted SYNONYM diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase
2003-10-27 Added SYNONYM diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase
2003-08-18 Deleted SYNONYM diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase
2002-11-27 Added DEFINITION Catalysis of the reaction: P(1),P(4)-bis(5'-guanosyl)tetraphosphate + H2O = GTP + GMP. Also acts on bis(5'-xanthosyl)-tetraphosphate and, more slowly, on bis(5'-adenosyl)-tetraphosphate and bis(5'-uridyl)-tetraphosphate.
2002-10-11 Added SYNONYM diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0008796 (bis(5'-nucleosyl)-tetraphosphatase activity)

Cross-references

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:22487
2003-10-27 Added XREF MetaCyc:3.6.1.17-RXN
2001-03-30 Added XREF EC:3.6.1.17
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