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GO:0004046 aminoacylase activity

Term Information

ID GO:0004046
Name aminoacylase activity
Ontology Molecular Function
Definition Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid.
GONUTS GO:0004046 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow dehydropeptidase II activity
exact N-acyl-L-amino-acid amidohydrolase activity
exact L-aminoacylase activity
exact L-amino-acid acylase activity
narrow acylase I activity
narrow aminoacylase I activity
related benzamidase activity
exact short acyl amidoacylase activity
exact long acyl amidoacylase activity
exact hippurase activity
exact amido acid deacylase activity
related histozyme activity
exact alpha-N-acylaminoacid hydrolase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 3.5.1.14
InterPro IPR010159
MetaCyc AMINOACYLASE-RXN
RHEA 15568

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004046:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO ID
Original GO Term Name
Evidence
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004046. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004046 based on the entire annotation set Co-occurrence statistics for GO:0004046 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:15568
2008-05-13 Added DEFINITION Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid.
2008-04-01 Updated RELATION is a GO:0016811 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides)
2007-11-08 Added SYNONYM L-amino-acid acylase activity
2007-11-08 Added SYNONYM L-aminoacylase activity
2007-11-08 Added SYNONYM N-acyl-L-amino-acid amidohydrolase activity
2007-11-08 Added SYNONYM alpha-N-acylaminoacid hydrolase activity
2007-11-08 Added SYNONYM amido acid deacylase activity
2007-11-08 Added SYNONYM hippurase activity
2007-11-08 Added SYNONYM long acyl amidoacylase activity
2007-11-08 Added SYNONYM short acyl amidoacylase activity
2007-09-06 Added SYNONYM acylase I activity
2007-09-06 Added SYNONYM aminoacylase I activity
2007-09-06 Added SYNONYM benzamidase activity
2007-09-06 Added SYNONYM dehydropeptidase II activity
2007-09-06 Added SYNONYM histozyme activity
2003-10-27 Added XREF MetaCyc:AMINOACYLASE-RXN
2003-03-19 Updated TERM aminoacylase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid.
2002-02-06 Updated TERM aminoacylase
2001-04-03 Updated TERM aminoacylase
2001-03-30 Added XREF EC:3.5.1.14
2001-03-30 Added TERM aminoacylase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM aminoacylase activity
2002-02-06 Updated TERM aminoacylase
2001-04-03 Updated TERM aminoacylase
2001-03-30 Added TERM aminoacylase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid.
2007-11-08 Added SYNONYM L-amino-acid acylase activity
2007-11-08 Added SYNONYM L-aminoacylase activity
2007-11-08 Added SYNONYM N-acyl-L-amino-acid amidohydrolase activity
2007-11-08 Added SYNONYM alpha-N-acylaminoacid hydrolase activity
2007-11-08 Added SYNONYM amido acid deacylase activity
2007-11-08 Added SYNONYM hippurase activity
2007-11-08 Added SYNONYM long acyl amidoacylase activity
2007-11-08 Added SYNONYM short acyl amidoacylase activity
2007-09-06 Added SYNONYM acylase I activity
2007-09-06 Added SYNONYM aminoacylase I activity
2007-09-06 Added SYNONYM benzamidase activity
2007-09-06 Added SYNONYM dehydropeptidase II activity
2007-09-06 Added SYNONYM histozyme activity
2002-11-27 Added DEFINITION Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016811 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides)

Cross-references

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:15568
2003-10-27 Added XREF MetaCyc:AMINOACYLASE-RXN
2001-03-30 Added XREF EC:3.5.1.14
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