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GO:0004045 aminoacyl-tRNA hydrolase activity

Term Information

ID GO:0004045
Name aminoacyl-tRNA hydrolase activity
Ontology Molecular Function
Definition Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.
Secondary IDs GO:0019850 GO:0019851
GONUTS GO:0004045 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact peptidyl-tRNA hydrolase activity
exact aminoacyl-tRNA hydrolase reaction
narrow D-tyrosyl-tRNA hydrolase activity
exact aminoacyl-transfer ribonucleate hydrolase activity
exact aminoacyl-tRNA aminoacylhydrolase activity
exact N-substituted aminoacyl transfer RNA hydrolase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 3.1.1.29
InterPro IPR001328
InterPro IPR002833
InterPro IPR018171
MetaCyc AMINOCYL-TRNA-HYDROLASE-RXN

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0006439 aminoacyl-tRNA hydrolase reaction REPLACEDBY GO:0004045

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004045:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004045. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004045 based on the entire annotation set Co-occurrence statistics for GO:0004045 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-05-03 Added RELATION is a GO:0052689 (carboxylic ester hydrolase activity)
2011-05-03 Deleted RELATION is a GO:0004091 (carboxylesterase activity)
2009-04-29 Added SECONDARY GO:0019851 (D-tyrosyl-tRNA hydrolase activity)
2009-04-29 Added SYNONYM D-tyrosyl-tRNA hydrolase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.
2008-04-01 Updated RELATION is a GO:0004091 (carboxylesterase activity)
2007-11-08 Added SYNONYM N-substituted aminoacyl transfer RNA hydrolase activity
2007-11-08 Added SYNONYM aminoacyl-tRNA aminoacylhydrolase activity
2007-11-08 Added SYNONYM aminoacyl-transfer ribonucleate hydrolase activity
2007-09-06 Added SYNONYM peptidyl-tRNA hydrolase activity
2007-09-06 Deleted SYNONYM peptidyl-tRNA hydrolase
2007-08-09 Added SYNONYM aminoacyl-tRNA hydrolase reaction
2007-08-09 Added SYNONYM peptidyl-tRNA hydrolase
2007-08-09 Deleted SYNONYM aminoacyl-tRNA hydrolase reaction
2007-08-09 Deleted SYNONYM peptidyl-tRNA hydrolase
2005-08-10 Added SYNONYM aminoacyl-tRNA hydrolase reaction
2004-04-19 Added SYNONYM peptidyl-tRNA hydrolase
2004-04-16 Deleted SYNONYM peptidyl-tRNA hydrolase
2003-10-27 Added SYNONYM peptidyl-tRNA hydrolase
2003-10-27 Added XREF MetaCyc:AMINOCYL-TRNA-HYDROLASE-RXN
2003-08-21 Deleted SYNONYM peptidyl-tRNA hydrolase
2003-03-26 Updated DEFINITION Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.
2003-03-19 Updated TERM aminoacyl-tRNA hydrolase activity
2002-11-27 Updated DEFINITION Catalysis of the hydrolysis of the peptidyl-tRNA released from the ribosomal P-site upon termination of translation. Considered part of the large ribosomal subunit.
2002-02-06 Updated TERM aminoacyl-tRNA hydrolase
2001-12-10 Added SYNONYM peptidyl-tRNA hydrolase
2001-08-06 Added DEFINITION enzyme catalyzing the hydrolysis of the peptidyl-tRNA released from the ribosomal P-site upon termination of translation. Considered part of the large ribosomal subunit.
2001-04-03 Updated TERM aminoacyl-tRNA hydrolase
2001-03-30 Added XREF EC:3.1.1.29
2001-03-30 Added TERM aminoacyl-tRNA hydrolase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM aminoacyl-tRNA hydrolase activity
2002-02-06 Updated TERM aminoacyl-tRNA hydrolase
2001-04-03 Updated TERM aminoacyl-tRNA hydrolase
2001-03-30 Added TERM aminoacyl-tRNA hydrolase

Definition/synonyms

Timestamp Action Category Detail
2009-04-29 Added SYNONYM D-tyrosyl-tRNA hydrolase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.
2007-11-08 Added SYNONYM N-substituted aminoacyl transfer RNA hydrolase activity
2007-11-08 Added SYNONYM aminoacyl-tRNA aminoacylhydrolase activity
2007-11-08 Added SYNONYM aminoacyl-transfer ribonucleate hydrolase activity
2007-09-06 Added SYNONYM peptidyl-tRNA hydrolase activity
2007-09-06 Deleted SYNONYM peptidyl-tRNA hydrolase
2007-08-09 Added SYNONYM aminoacyl-tRNA hydrolase reaction
2007-08-09 Added SYNONYM peptidyl-tRNA hydrolase
2007-08-09 Deleted SYNONYM aminoacyl-tRNA hydrolase reaction
2007-08-09 Deleted SYNONYM peptidyl-tRNA hydrolase
2005-08-10 Added SYNONYM aminoacyl-tRNA hydrolase reaction
2004-04-19 Added SYNONYM peptidyl-tRNA hydrolase
2004-04-16 Deleted SYNONYM peptidyl-tRNA hydrolase
2003-10-27 Added SYNONYM peptidyl-tRNA hydrolase
2003-08-21 Deleted SYNONYM peptidyl-tRNA hydrolase
2003-03-26 Updated DEFINITION Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.
2002-11-27 Updated DEFINITION Catalysis of the hydrolysis of the peptidyl-tRNA released from the ribosomal P-site upon termination of translation. Considered part of the large ribosomal subunit.
2001-12-10 Added SYNONYM peptidyl-tRNA hydrolase
2001-08-06 Added DEFINITION enzyme catalyzing the hydrolysis of the peptidyl-tRNA released from the ribosomal P-site upon termination of translation. Considered part of the large ribosomal subunit.

Relationships

Timestamp Action Category Detail
2011-05-03 Added RELATION is a GO:0052689 (carboxylic ester hydrolase activity)
2011-05-03 Deleted RELATION is a GO:0004091 (carboxylesterase activity)
2008-04-01 Updated RELATION is a GO:0004091 (carboxylesterase activity)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:AMINOCYL-TRNA-HYDROLASE-RXN
2001-03-30 Added XREF EC:3.1.1.29

Other

Timestamp Action Category Detail
2009-04-29 Added SECONDARY GO:0019851 (D-tyrosyl-tRNA hydrolase activity)
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