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GO:0004040 amidase activity

Term Information

ID GO:0004040
Name amidase activity
Ontology Molecular Function
Definition Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.
GONUTS GO:0004040 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact amidohydrolase activity
exact acylamide amidohydrolase activity
exact acylase activity
exact acylamidase activity
exact fatty acylamidase activity
exact N-acetylaminohydrolase activity
exact acetamidase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 3.5.1.4
InterPro IPR002901
InterPro IPR023719
MetaCyc AMIDASE-RXN
UM-BBD_enzymeID e0068

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004040:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Original GO ID
Original GO Term Name
Evidence
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004040. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004040 based on the entire annotation set Co-occurrence statistics for GO:0004040 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.
2008-04-01 Updated RELATION is a GO:0016811 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides)
2007-11-08 Added SYNONYM N-acetylaminohydrolase activity
2007-11-08 Added SYNONYM acetamidase activity
2007-11-08 Added SYNONYM acylamide amidohydrolase activity
2007-11-08 Added SYNONYM amidohydrolase activity
2007-11-08 Added SYNONYM fatty acylamidase activity
2007-11-08 Deleted SYNONYM acetamidase
2007-09-06 Added SYNONYM acylamidase activity
2007-09-06 Added SYNONYM acylase activity
2007-08-09 Added SYNONYM acetamidase
2007-08-09 Deleted SYNONYM acetamidase
2004-04-19 Added SYNONYM acetamidase
2004-04-16 Deleted SYNONYM acetamidase
2003-10-30 Updated DEFINITION Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.
2003-10-27 Added SYNONYM acetamidase
2003-10-27 Added XREF UM-BBD_enzymeID:e0068
2003-10-27 Added XREF MetaCyc:AMIDASE-RXN
2003-03-19 Updated TERM amidase activity
2003-03-19 Deleted SYNONYM acetamidase
2002-11-27 Added DEFINITION Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + ammonia.
2002-02-06 Updated TERM amidase
2001-04-03 Updated TERM amidase
2001-03-30 Added XREF EC:3.5.1.4
2001-03-30 Added SYNONYM acetamidase
2001-03-30 Added TERM amidase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM amidase activity
2002-02-06 Updated TERM amidase
2001-04-03 Updated TERM amidase
2001-03-30 Added TERM amidase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.
2007-11-08 Added SYNONYM N-acetylaminohydrolase activity
2007-11-08 Added SYNONYM acetamidase activity
2007-11-08 Added SYNONYM acylamide amidohydrolase activity
2007-11-08 Added SYNONYM amidohydrolase activity
2007-11-08 Added SYNONYM fatty acylamidase activity
2007-11-08 Deleted SYNONYM acetamidase
2007-09-06 Added SYNONYM acylamidase activity
2007-09-06 Added SYNONYM acylase activity
2007-08-09 Added SYNONYM acetamidase
2007-08-09 Deleted SYNONYM acetamidase
2004-04-19 Added SYNONYM acetamidase
2004-04-16 Deleted SYNONYM acetamidase
2003-10-30 Updated DEFINITION Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.
2003-10-27 Added SYNONYM acetamidase
2003-03-19 Deleted SYNONYM acetamidase
2002-11-27 Added DEFINITION Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + ammonia.
2001-03-30 Added SYNONYM acetamidase

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016811 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF UM-BBD_enzymeID:e0068
2003-10-27 Added XREF MetaCyc:AMIDASE-RXN
2001-03-30 Added XREF EC:3.5.1.4
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