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GO:0004029 aldehyde dehydrogenase (NAD) activity

Term Information

ID GO:0004029
Name aldehyde dehydrogenase (NAD) activity
Ontology Molecular Function
Definition Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
GONUTS GO:0004029 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact CoA-independent aldehyde dehydrogenase activity
exact NAD-aldehyde dehydrogenase activity
exact NAD-dependent 4-hydroxynonenal dehydrogenase activity
exact NAD-dependent aldehyde dehydrogenase activity
exact propionaldehyde dehydrogenase activity
exact aldehyde dehydrogenase (NAD+)
exact aldehyde:NAD+ oxidoreductase activity
exact m-methylbenzaldehyde dehydrogenase activity
exact NAD-linked aldehyde dehydrogenase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.2.1.3
MetaCyc ALDHDEHYDROG-RXN
RHEA 16188
UM-BBD_enzymeID e0024
Wikipedia Aldehyde_dehydrogenase_(NAD+)

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004029:
Relationship To GO:0004029 Child Term Child Term Name
Is a GO:0008802 betaine-aldehyde dehydrogenase activity
Is a GO:0008911 lactaldehyde dehydrogenase activity
Is a GO:0008957 phenylacetaldehyde dehydrogenase activity
Is a GO:0018467 formaldehyde dehydrogenase activity
Is a GO:0018474 2-carboxybenzaldehyde dehydrogenase activity
Is a GO:0018479 benzaldehyde dehydrogenase (NAD+) activity
Is a GO:0018484 4-hydroxybenzaldehyde dehydrogenase activity
Is a GO:0018485 salicylaldehyde dehydrogenase activity
Is a GO:0019108 aryl-aldehyde dehydrogenase (NAD) activity
Is a GO:0019145 aminobutyraldehyde dehydrogenase activity
Is a GO:0033723 fluoroacetaldehyde dehydrogenase activity
Is a GO:0034520 2-naphthaldehyde dehydrogenase activity
Is a GO:0034530 4-hydroxymethylsalicyaldehyde dehydrogenase activity
Is a GO:0047106 4-hydroxyphenylacetaldehyde dehydrogenase activity
Is a GO:0047107 gamma-guanidinobutyraldehyde dehydrogenase activity
Is a GO:0047551 2-oxoaldehyde dehydrogenase (NAD) activity
Is a GO:0050061 long-chain-aldehyde dehydrogenase activity
Is a GO:0050569 glycolaldehyde dehydrogenase activity
Is a GO:0052814 medium-chain-aldehyde dehydrogenase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
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Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004029. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004029 based on the entire annotation set Co-occurrence statistics for GO:0004029 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:16188
2011-04-18 Added RELATION is a GO:0016620 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)
2011-04-18 Deleted RELATION is a GO:0004030 (aldehyde dehydrogenase [NAD(P)+] activity)
2010-10-08 Added RELATION is a GO:0004030 (aldehyde dehydrogenase [NAD(P)+] activity)
2010-10-08 Deleted RELATION is a GO:0016620 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)
2009-02-25 Added XREF Wikipedia:Aldehyde_dehydrogenase_(NAD+)
2008-05-13 Added DEFINITION Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
2008-04-01 Updated RELATION is a GO:0016620 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)
2007-11-08 Added SYNONYM CoA-independent aldehyde dehydrogenase activity
2007-11-08 Added SYNONYM NAD-aldehyde dehydrogenase activity
2007-11-08 Added SYNONYM NAD-dependent 4-hydroxynonenal dehydrogenase activity
2007-11-08 Added SYNONYM NAD-dependent aldehyde dehydrogenase activity
2007-11-08 Added SYNONYM NAD-linked aldehyde dehydrogenase activity
2007-11-08 Added SYNONYM aldehyde dehydrogenase (NAD+)
2007-11-08 Added SYNONYM aldehyde:NAD+ oxidoreductase activity
2007-11-08 Added SYNONYM m-methylbenzaldehyde dehydrogenase activity
2007-11-08 Added SYNONYM propionaldehyde dehydrogenase activity
2003-10-27 Added XREF UM-BBD_enzymeID:e0024
2003-10-27 Added XREF MetaCyc:ALDHDEHYDROG-RXN
2003-09-06 Updated TERM aldehyde dehydrogenase (NAD) activity
2003-03-19 Updated TERM aldehyde dehydrogenase (NAD+) activity
2002-11-27 Added DEFINITION Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
2002-02-06 Updated TERM aldehyde dehydrogenase (NAD+)
2001-04-03 Updated TERM aldehyde dehydrogenase (NAD+)
2001-03-30 Added XREF EC:1.2.1.3
2001-03-30 Added TERM aldehyde dehydrogenase (NAD+)

Term

Timestamp Action Category Detail
2003-09-06 Updated TERM aldehyde dehydrogenase (NAD) activity
2003-03-19 Updated TERM aldehyde dehydrogenase (NAD+) activity
2002-02-06 Updated TERM aldehyde dehydrogenase (NAD+)
2001-04-03 Updated TERM aldehyde dehydrogenase (NAD+)
2001-03-30 Added TERM aldehyde dehydrogenase (NAD+)

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
2007-11-08 Added SYNONYM CoA-independent aldehyde dehydrogenase activity
2007-11-08 Added SYNONYM NAD-aldehyde dehydrogenase activity
2007-11-08 Added SYNONYM NAD-dependent 4-hydroxynonenal dehydrogenase activity
2007-11-08 Added SYNONYM NAD-dependent aldehyde dehydrogenase activity
2007-11-08 Added SYNONYM NAD-linked aldehyde dehydrogenase activity
2007-11-08 Added SYNONYM aldehyde dehydrogenase (NAD+)
2007-11-08 Added SYNONYM aldehyde:NAD+ oxidoreductase activity
2007-11-08 Added SYNONYM m-methylbenzaldehyde dehydrogenase activity
2007-11-08 Added SYNONYM propionaldehyde dehydrogenase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.

Relationships

Timestamp Action Category Detail
2011-04-18 Added RELATION is a GO:0016620 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)
2011-04-18 Deleted RELATION is a GO:0004030 (aldehyde dehydrogenase [NAD(P)+] activity)
2010-10-08 Added RELATION is a GO:0004030 (aldehyde dehydrogenase [NAD(P)+] activity)
2010-10-08 Deleted RELATION is a GO:0016620 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)
2008-04-01 Updated RELATION is a GO:0016620 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)

Cross-references

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:16188
2009-02-25 Added XREF Wikipedia:Aldehyde_dehydrogenase_(NAD+)
2003-10-27 Added XREF UM-BBD_enzymeID:e0024
2003-10-27 Added XREF MetaCyc:ALDHDEHYDROG-RXN
2001-03-30 Added XREF EC:1.2.1.3
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