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GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity

Term Information

ID GO:0004021
Name L-alanine:2-oxoglutarate aminotransferase activity
Ontology Molecular Function
Definition Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate.
GONUTS GO:0004021 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad alanine aminotransferase activity
exact glutamic--alanine transaminase activity
exact glutamic--pyruvic transaminase activity
exact pyruvate-alanine aminotransferase activity
broad L-alanine transaminase activity
broad L-alanine aminotransferase activity
broad pyruvate transaminase activity
broad alanine transaminase activity
exact pyruvate-glutamate transaminase activity
related ALT
related GPT
exact L-alanine-alpha-ketoglutarate aminotransferase activity
exact alanine-alpha-ketoglutarate aminotransferase activity
exact alanine-pyruvate aminotransferase activity
broad beta-alanine aminotransferase
exact glutamic-pyruvic aminotransferase activity
exact glutamic acid-pyruvic acid transaminase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.6.1.2
KEGG R00258
MetaCyc ALANINE-AMINOTRANSFERASE-RXN
RHEA 19456

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004021:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004021. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004021 based on the entire annotation set Co-occurrence statistics for GO:0004021 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-11 Added DEFINITION Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate.
2010-10-11 Deleted DEFINITION Catalysis of the reaction: L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.
2010-10-11 Added XREF RHEA:19456
2010-10-11 Added XREF KEGG:R00258
2009-03-26 Updated TERM L-alanine:2-oxoglutarate aminotransferase activity
2009-03-26 Deleted SYNONYM alanine aminotransferase activity
2009-03-26 Deleted SYNONYM L-alanine aminotransferase activity
2009-03-26 Deleted SYNONYM L-alanine transaminase activity
2009-03-26 Deleted SYNONYM L-alanine:2-oxoglutarate aminotransferase activity
2009-03-26 Deleted SYNONYM pyruvate transaminase activity
2009-03-26 Added SYNONYM L-alanine aminotransferase activity
2009-03-26 Added SYNONYM L-alanine transaminase activity
2009-03-26 Added SYNONYM alanine aminotransferase activity
2009-03-26 Added SYNONYM alanine transaminase activity
2009-03-26 Added SYNONYM pyruvate transaminase activity
2009-03-26 Added RELATION is a GO:0047635 (alanine-oxo-acid transaminase activity)
2009-03-26 Deleted RELATION is a GO:0008483 (transaminase activity)
2008-05-13 Added DEFINITION Catalysis of the reaction: L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.
2008-04-01 Updated RELATION is a GO:0008483 (transaminase activity)
2007-11-08 Added SYNONYM ALT
2007-11-08 Added SYNONYM GPT
2007-11-08 Added SYNONYM L-alanine aminotransferase activity
2007-11-08 Added SYNONYM L-alanine transaminase activity
2007-11-08 Added SYNONYM L-alanine-alpha-ketoglutarate aminotransferase activity
2007-11-08 Added SYNONYM L-alanine:2-oxoglutarate aminotransferase activity
2007-11-08 Added SYNONYM alanine-alpha-ketoglutarate aminotransferase activity
2007-11-08 Added SYNONYM alanine-pyruvate aminotransferase activity
2007-11-08 Added SYNONYM beta-alanine aminotransferase
2007-11-08 Added SYNONYM glutamic acid-pyruvic acid transaminase activity
2007-11-08 Added SYNONYM glutamic-pyruvic aminotransferase activity
2007-11-08 Added SYNONYM pyruvate transaminase activity
2007-11-08 Added SYNONYM pyruvate-alanine aminotransferase activity
2007-11-08 Added SYNONYM pyruvate-glutamate transaminase activity
2007-09-06 Added SYNONYM glutamic--alanine transaminase activity
2007-09-06 Added SYNONYM glutamic--pyruvic transaminase activity
2007-08-09 Added SYNONYM alanine aminotransferase activity
2007-08-09 Deleted SYNONYM alanine aminotransferase activity
2004-04-19 Added SYNONYM alanine aminotransferase activity
2004-04-16 Deleted SYNONYM alanine aminotransferase activity
2003-10-27 Added SYNONYM alanine aminotransferase activity
2003-10-27 Added XREF MetaCyc:ALANINE-AMINOTRANSFERASE-RXN
2003-09-09 Updated TERM alanine transaminase activity
2003-03-19 Updated TERM alanine aminotransferase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.
2002-02-06 Updated TERM alanine aminotransferase
2001-04-03 Updated TERM alanine aminotransferase
2001-03-30 Added XREF EC:2.6.1.2
2001-03-30 Added TERM alanine aminotransferase

Term

Timestamp Action Category Detail
2009-03-26 Updated TERM L-alanine:2-oxoglutarate aminotransferase activity
2003-09-09 Updated TERM alanine transaminase activity
2003-03-19 Updated TERM alanine aminotransferase activity
2002-02-06 Updated TERM alanine aminotransferase
2001-04-03 Updated TERM alanine aminotransferase
2001-03-30 Added TERM alanine aminotransferase

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Added DEFINITION Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate.
2010-10-11 Deleted DEFINITION Catalysis of the reaction: L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.
2009-03-26 Deleted SYNONYM alanine aminotransferase activity
2009-03-26 Deleted SYNONYM L-alanine aminotransferase activity
2009-03-26 Deleted SYNONYM L-alanine transaminase activity
2009-03-26 Deleted SYNONYM L-alanine:2-oxoglutarate aminotransferase activity
2009-03-26 Deleted SYNONYM pyruvate transaminase activity
2009-03-26 Added SYNONYM L-alanine aminotransferase activity
2009-03-26 Added SYNONYM L-alanine transaminase activity
2009-03-26 Added SYNONYM alanine aminotransferase activity
2009-03-26 Added SYNONYM alanine transaminase activity
2009-03-26 Added SYNONYM pyruvate transaminase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.
2007-11-08 Added SYNONYM ALT
2007-11-08 Added SYNONYM GPT
2007-11-08 Added SYNONYM L-alanine aminotransferase activity
2007-11-08 Added SYNONYM L-alanine transaminase activity
2007-11-08 Added SYNONYM L-alanine-alpha-ketoglutarate aminotransferase activity
2007-11-08 Added SYNONYM L-alanine:2-oxoglutarate aminotransferase activity
2007-11-08 Added SYNONYM alanine-alpha-ketoglutarate aminotransferase activity
2007-11-08 Added SYNONYM alanine-pyruvate aminotransferase activity
2007-11-08 Added SYNONYM beta-alanine aminotransferase
2007-11-08 Added SYNONYM glutamic acid-pyruvic acid transaminase activity
2007-11-08 Added SYNONYM glutamic-pyruvic aminotransferase activity
2007-11-08 Added SYNONYM pyruvate transaminase activity
2007-11-08 Added SYNONYM pyruvate-alanine aminotransferase activity
2007-11-08 Added SYNONYM pyruvate-glutamate transaminase activity
2007-09-06 Added SYNONYM glutamic--alanine transaminase activity
2007-09-06 Added SYNONYM glutamic--pyruvic transaminase activity
2007-08-09 Added SYNONYM alanine aminotransferase activity
2007-08-09 Deleted SYNONYM alanine aminotransferase activity
2004-04-19 Added SYNONYM alanine aminotransferase activity
2004-04-16 Deleted SYNONYM alanine aminotransferase activity
2003-10-27 Added SYNONYM alanine aminotransferase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.

Relationships

Timestamp Action Category Detail
2009-03-26 Added RELATION is a GO:0047635 (alanine-oxo-acid transaminase activity)
2009-03-26 Deleted RELATION is a GO:0008483 (transaminase activity)
2008-04-01 Updated RELATION is a GO:0008483 (transaminase activity)

Cross-references

Timestamp Action Category Detail
2010-10-11 Added XREF RHEA:19456
2010-10-11 Added XREF KEGG:R00258
2003-10-27 Added XREF MetaCyc:ALANINE-AMINOTRANSFERASE-RXN
2001-03-30 Added XREF EC:2.6.1.2
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