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GO:0004016 adenylate cyclase activity

Term Information

ID GO:0004016
Name adenylate cyclase activity
Ontology Molecular Function
Definition Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
GONUTS GO:0004016 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact adenyl cyclase activity
exact ATP pyrophosphate-lyase activity
exact 3',5'-cyclic AMP synthetase activity
exact ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) activity
exact adenylylcyclase activity
exact ATP diphosphate-lyase (cyclizing) activity
related cAMP generating peptide activity
exact adenylyl cyclase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 4.6.1.1
InterPro IPR000274
InterPro IPR009398
InterPro IPR013716
InterPro IPR016577
MetaCyc ADENYLATECYC-RXN
RHEA 15392

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0008492 cAMP generating peptide activity CONSIDER GO:0004016

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004016:
Relationship To GO:0004016 Child Term Child Term Name
Is a GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity
Negatively regulates GO:0007194 negative regulation of adenylate cyclase activity
Regulates GO:0045761 regulation of adenylate cyclase activity
Positively regulates GO:0045762 positive regulation of adenylate cyclase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO ID
Original GO Term Name
Evidence
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004016. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004016 based on the entire annotation set Co-occurrence statistics for GO:0004016 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:15392
2010-06-15 Added RELATION part of GO:0006171 (cAMP biosynthetic process)
2010-06-14 Deleted RELATION part of GO:0006171 (cAMP biosynthetic process)
2010-06-08 Added RELATION part of GO:0006171 (cAMP biosynthetic process)
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
2008-04-01 Updated RELATION is a GO:0016849 (phosphorus-oxygen lyase activity)
2008-04-01 Updated RELATION is a GO:0009975 (cyclase activity)
2007-12-14 Added SYNONYM ATP diphosphate-lyase (cyclizing) activity
2007-12-14 Added SYNONYM ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) activity
2007-12-14 Added SYNONYM adenylylcyclase activity
2007-09-06 Added SYNONYM 3',5'-cyclic AMP synthetase activity
2007-09-06 Added SYNONYM ATP pyrophosphate-lyase activity
2007-09-06 Added SYNONYM adenyl cyclase activity
2007-08-09 Added SYNONYM adenylyl cyclase activity
2007-08-09 Added SYNONYM cAMP generating peptide activity
2007-08-09 Deleted SYNONYM adenylyl cyclase activity
2007-08-09 Deleted SYNONYM cAMP generating peptide activity
2005-08-10 Added SYNONYM cAMP generating peptide activity
2004-09-03 Added SYNONYM adenylyl cyclase activity
2003-10-27 Added XREF MetaCyc:ADENYLATECYC-RXN
2003-03-19 Updated TERM adenylate cyclase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
2002-02-06 Updated TERM adenylate cyclase
2001-04-03 Updated TERM adenylate cyclase
2001-03-30 Added XREF EC:4.6.1.1
2001-03-30 Added TERM adenylate cyclase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM adenylate cyclase activity
2002-02-06 Updated TERM adenylate cyclase
2001-04-03 Updated TERM adenylate cyclase
2001-03-30 Added TERM adenylate cyclase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
2007-12-14 Added SYNONYM ATP diphosphate-lyase (cyclizing) activity
2007-12-14 Added SYNONYM ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) activity
2007-12-14 Added SYNONYM adenylylcyclase activity
2007-09-06 Added SYNONYM 3',5'-cyclic AMP synthetase activity
2007-09-06 Added SYNONYM ATP pyrophosphate-lyase activity
2007-09-06 Added SYNONYM adenyl cyclase activity
2007-08-09 Added SYNONYM adenylyl cyclase activity
2007-08-09 Added SYNONYM cAMP generating peptide activity
2007-08-09 Deleted SYNONYM adenylyl cyclase activity
2007-08-09 Deleted SYNONYM cAMP generating peptide activity
2005-08-10 Added SYNONYM cAMP generating peptide activity
2004-09-03 Added SYNONYM adenylyl cyclase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.

Relationships

Timestamp Action Category Detail
2010-06-15 Added RELATION part of GO:0006171 (cAMP biosynthetic process)
2010-06-14 Deleted RELATION part of GO:0006171 (cAMP biosynthetic process)
2010-06-08 Added RELATION part of GO:0006171 (cAMP biosynthetic process)
2008-04-01 Updated RELATION is a GO:0016849 (phosphorus-oxygen lyase activity)
2008-04-01 Updated RELATION is a GO:0009975 (cyclase activity)

Cross-references

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:15392
2003-10-27 Added XREF MetaCyc:ADENYLATECYC-RXN
2001-03-30 Added XREF EC:4.6.1.1
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