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GO:0003994 aconitate hydratase activityCatalysis of the reaction: citrate = cis-aconitate + H2O = isocitrate; i.e. the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.
Term Information
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| Type | Synonym |
| exact | citrate(isocitrate) hydro-lyase activity |
| broad | citrate hydro-lyase activity |
| exact | cis-aconitase activity |
| exact | aconitase activity |
| exact | citrate(isocitrate) hydro-lyase (cis-aconitate-forming) |
| Database | ID |
| MetaCyc | ACONITATEDEHYDR-RXN |
| INTERPRO | IPR015929 |
| INTERPRO | IPR015933 |
| INTERPRO | IPR004406 |
| INTERPRO | IPR006248 |
| INTERPRO | IPR015930 |
| EC | 4.2.1.3 |
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| GO:0003674 molecular_function | |||||
![]() | GO:0003824 catalytic activity | ||||
![]() | ![]() | GO:0016829 lyase activity | |||
![]() | ![]() | ![]() | GO:0016835 carbon-oxygen lyase activity | ||
![]() | ![]() | ![]() | ![]() | GO:0016836 hydro-lyase activity | |
![]() | ![]() | ![]() | ![]() | ![]() | GO:0003994 aconitate hydratase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-21-04-03-45 |