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GO:0003994 aconitate hydratase activity

Catalysis of the reaction: citrate = cis-aconitate + H2O = isocitrate; i.e. the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.

Term Information

ID GO:0003994
Name aconitate hydratase activity
Ontology Molecular Function
Definition Catalysis of the reaction: citrate = cis-aconitate + H2O = isocitrate; i.e. the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.
Comment

Synonyms

Type Synonym
exact citrate(isocitrate) hydro-lyase activity
broad citrate hydro-lyase activity
exact cis-aconitase activity
exact aconitase activity
exact citrate(isocitrate) hydro-lyase (cis-aconitate-forming)

Cross-references associated with this term:

Database ID
MetaCyc ACONITATEDEHYDR-RXN
INTERPRO IPR015929
INTERPRO IPR015933
INTERPRO IPR004406
INTERPRO IPR006248
INTERPRO IPR015930
EC 4.2.1.3

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Ancestor Table

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0016835 carbon-oxygen lyase activity
GO:0016836 hydro-lyase activity
GO:0003994 aconitate hydratase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

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Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

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