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GO:0003968 RNA-directed RNA polymerase activity

Term Information

ID GO:0003968
Name RNA-directed RNA polymerase activity
Ontology Molecular Function
Definition Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template.
GONUTS GO:0003968 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact RNA-dependent RNA polymerase activity
related RDRP
exact RNA-dependent ribonucleate nucleotidyltransferase activity
exact nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)
narrow phage f2 replicase
related polymerase L
exact ribonucleic acid replicase activity
exact ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity
exact ribonucleic acid-dependent ribonucleic acid polymerase activity
exact ribonucleic replicase activity
broad transcriptase
exact Q-beta replicase activity
related PB2 proteins
related PB1 proteins
exact 3D polymerase activity
related ribonucleic synthetase activity
related RNA synthetase activity
exact RNA nucleotidyltransferase (RNA-directed) activity
exact RNA replicase activity
exact RNA-dependent RNA replicase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.7.7.48
InterPro IPR000208
InterPro IPR000224
InterPro IPR001009
InterPro IPR001205
InterPro IPR001407
InterPro IPR001490
InterPro IPR001528
InterPro IPR001591
InterPro IPR001788
InterPro IPR001795
InterPro IPR002166
InterPro IPR002507
InterPro IPR002518
InterPro IPR002527
InterPro IPR002693
InterPro IPR002705
InterPro IPR002868
InterPro IPR003487
InterPro IPR004004
InterPro IPR004259
InterPro IPR005093
InterPro IPR007094
InterPro IPR007096
InterPro IPR007097
InterPro IPR007098
InterPro IPR007099
InterPro IPR007100
InterPro IPR007322
InterPro IPR007610
InterPro IPR007855
InterPro IPR008041
InterPro IPR008043
InterPro IPR008723
InterPro IPR008738
InterPro IPR008744
InterPro IPR009466
InterPro IPR009469
InterPro IPR010453
InterPro IPR012915
InterPro IPR013016
InterPro IPR013614
InterPro IPR013648
InterPro IPR013674
InterPro IPR013707
InterPro IPR014023
InterPro IPR014385
InterPro IPR014412
InterPro IPR014838
InterPro IPR016075
InterPro IPR016268
InterPro IPR021824
InterPro IPR022071
InterPro IPR022120
InterPro IPR022230
InterPro IPR022245
InterPro IPR022531
MetaCyc RNA-DIRECTED-RNA-POLYMERASE-RXN
UniProtKB-KW RNA-directed RNA polymerase

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0003968:
Relationship To GO:0003968 Child Term Child Term Name
Regulates GO:1900259 regulation of RNA-directed RNA polymerase activity
Negatively regulates GO:1900260 negative regulation of RNA-directed RNA polymerase activity
Positively regulates GO:1900261 positive regulation of RNA-directed RNA polymerase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0003968. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0003968 based on the entire annotation set Co-occurrence statistics for GO:0003968 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-02-07 Deleted RELATION has part GO:0001171 (reverse transcription)
2013-10-30 Deleted RELATION has part GO:0039691 (double stranded viral RNA replication)
2013-10-30 Deleted RELATION has part GO:0039689 (negative stranded viral RNA replication)
2013-10-30 Added RELATION has part GO:0001171 (reverse transcription)
2013-10-25 Added RELATION has part GO:0039691 (double stranded viral RNA replication)
2013-10-25 Added RELATION part of GO:0001172 (transcription, RNA-templated)
2013-10-23 Added RELATION has part GO:0039689 (negative stranded viral RNA replication)
2010-09-03 Added DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template.
2010-09-03 Deleted DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA (n) = diphosphate + RNA (n+1); uses an RNA template.
2008-05-13 Added DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA (n) = diphosphate + RNA (n+1); uses an RNA template.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA (n) = diphosphate + RNA (n+1); uses an RNA template.
2008-04-01 Updated RELATION is a GO:0034062 (RNA polymerase activity)
2008-01-07 Added SYNONYM RNA synthetase activity
2008-01-07 Added SYNONYM ribonucleic synthetase activity
2008-01-07 Deleted SYNONYM RNA transcriptase
2008-01-07 Deleted SYNONYM ribonucleic synthetase activity
2008-01-07 Deleted SYNONYM RNA synthetase activity
2007-11-08 Added SYNONYM 3D polymerase activity
2007-11-08 Added SYNONYM PB1 proteins
2007-11-08 Added SYNONYM PB2 proteins
2007-11-08 Added SYNONYM Q-beta replicase activity
2007-11-08 Added SYNONYM RDRP
2007-11-08 Added SYNONYM RNA replicase activity
2007-11-08 Added SYNONYM RNA synthetase activity
2007-11-08 Added SYNONYM RNA transcriptase
2007-11-08 Added SYNONYM RNA-dependent RNA polymerase activity
2007-11-08 Added SYNONYM RNA-dependent RNA replicase activity
2007-11-08 Added SYNONYM RNA-dependent ribonucleate nucleotidyltransferase activity
2007-11-08 Added SYNONYM nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)
2007-11-08 Added SYNONYM phage f2 replicase
2007-11-08 Added SYNONYM polymerase L
2007-11-08 Added SYNONYM ribonucleic acid replicase activity
2007-11-08 Added SYNONYM ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity
2007-11-08 Added SYNONYM ribonucleic acid-dependent ribonucleic acid polymerase activity
2007-11-08 Added SYNONYM ribonucleic replicase activity
2007-11-08 Added SYNONYM ribonucleic synthetase activity
2007-11-08 Added SYNONYM transcriptase
2007-09-06 Added SYNONYM RNA nucleotidyltransferase (RNA-directed) activity
2006-01-24 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA (n) = diphosphate + RNA (n+1); uses an RNA template.
2005-04-27 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA (n) = diphosphate + RNA (n+1), using an RNA template.
2003-10-27 Added XREF MetaCyc:RNA-DIRECTED-RNA-POLYMERASE-RXN
2003-03-19 Updated TERM RNA-directed RNA polymerase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA (n) = diphosphate + RNA (n+1).
2002-02-06 Updated TERM RNA-directed RNA polymerase
2001-04-03 Updated TERM RNA-directed RNA polymerase
2001-03-30 Added XREF EC:2.7.7.48
2001-03-30 Added TERM RNA-directed RNA polymerase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM RNA-directed RNA polymerase activity
2002-02-06 Updated TERM RNA-directed RNA polymerase
2001-04-03 Updated TERM RNA-directed RNA polymerase
2001-03-30 Added TERM RNA-directed RNA polymerase

Definition/synonyms

Timestamp Action Category Detail
2010-09-03 Added DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template.
2010-09-03 Deleted DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA (n) = diphosphate + RNA (n+1); uses an RNA template.
2008-05-13 Added DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA (n) = diphosphate + RNA (n+1); uses an RNA template.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA (n) = diphosphate + RNA (n+1); uses an RNA template.
2008-01-07 Added SYNONYM RNA synthetase activity
2008-01-07 Added SYNONYM ribonucleic synthetase activity
2008-01-07 Deleted SYNONYM RNA transcriptase
2008-01-07 Deleted SYNONYM ribonucleic synthetase activity
2008-01-07 Deleted SYNONYM RNA synthetase activity
2007-11-08 Added SYNONYM 3D polymerase activity
2007-11-08 Added SYNONYM PB1 proteins
2007-11-08 Added SYNONYM PB2 proteins
2007-11-08 Added SYNONYM Q-beta replicase activity
2007-11-08 Added SYNONYM RDRP
2007-11-08 Added SYNONYM RNA replicase activity
2007-11-08 Added SYNONYM RNA synthetase activity
2007-11-08 Added SYNONYM RNA transcriptase
2007-11-08 Added SYNONYM RNA-dependent RNA polymerase activity
2007-11-08 Added SYNONYM RNA-dependent RNA replicase activity
2007-11-08 Added SYNONYM RNA-dependent ribonucleate nucleotidyltransferase activity
2007-11-08 Added SYNONYM nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)
2007-11-08 Added SYNONYM phage f2 replicase
2007-11-08 Added SYNONYM polymerase L
2007-11-08 Added SYNONYM ribonucleic acid replicase activity
2007-11-08 Added SYNONYM ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity
2007-11-08 Added SYNONYM ribonucleic acid-dependent ribonucleic acid polymerase activity
2007-11-08 Added SYNONYM ribonucleic replicase activity
2007-11-08 Added SYNONYM ribonucleic synthetase activity
2007-11-08 Added SYNONYM transcriptase
2007-09-06 Added SYNONYM RNA nucleotidyltransferase (RNA-directed) activity
2006-01-24 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA (n) = diphosphate + RNA (n+1); uses an RNA template.
2005-04-27 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA (n) = diphosphate + RNA (n+1), using an RNA template.
2002-11-27 Added DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA (n) = diphosphate + RNA (n+1).

Relationships

Timestamp Action Category Detail
2014-02-07 Deleted RELATION has part GO:0001171 (reverse transcription)
2013-10-30 Deleted RELATION has part GO:0039691 (double stranded viral RNA replication)
2013-10-30 Deleted RELATION has part GO:0039689 (negative stranded viral RNA replication)
2013-10-30 Added RELATION has part GO:0001171 (reverse transcription)
2013-10-25 Added RELATION has part GO:0039691 (double stranded viral RNA replication)
2013-10-25 Added RELATION part of GO:0001172 (transcription, RNA-templated)
2013-10-23 Added RELATION has part GO:0039689 (negative stranded viral RNA replication)
2008-04-01 Updated RELATION is a GO:0034062 (RNA polymerase activity)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:RNA-DIRECTED-RNA-POLYMERASE-RXN
2001-03-30 Added XREF EC:2.7.7.48
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