spacer

GO:0003964 RNA-directed DNA polymerase activity

Term Information

ID GO:0003964
Name RNA-directed DNA polymerase activity
Ontology Molecular Function
Definition Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.
GONUTS GO:0003964 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) activity
related RT
exact RNA-instructed DNA polymerase activity
exact RNA-dependent deoxyribonucleate nucleotidyltransferase activity
exact RNA revertase activity
narrow RNA-directed DNA polymerase, transposon encoded
narrow RNA-directed DNA polymerase, group II intron encoded
exact RNA-dependent DNA polymerase activity
related revertase activity
exact reverse transcriptase activity
exact DNA nucleotidyltransferase (RNA-directed) activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.7.7.49
InterPro IPR000123
InterPro IPR003286
InterPro IPR010659
InterPro IPR010661
InterPro IPR021891
MetaCyc RNA-DIRECTED-DNA-POLYMERASE-RXN
UniProtKB-KW RNA-directed DNA polymerase

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0003966 RNA-directed DNA polymerase, transposon encoded REPLACEDBY GO:0003964
GO:0003967 RNA-directed DNA polymerase, group II intron encoded REPLACEDBY GO:0003964

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0003964:
Relationship To GO:0003964 Child Term Child Term Name
Is a GO:0003720 telomerase activity
Is a GO:0003721 telomeric template RNA reverse transcriptase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0003964. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0003964 based on the entire annotation set Co-occurrence statistics for GO:0003964 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-02-07 Added RELATION has part GO:0001171 (reverse transcription)
2013-10-25 Added RELATION part of GO:0006278 (RNA-dependent DNA replication)
2008-05-13 Added DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.
2008-04-01 Updated RELATION is a GO:0034061 (DNA polymerase activity)
2007-12-14 Added SYNONYM RNA-dependent deoxyribonucleate nucleotidyltransferase activity
2007-12-14 Added SYNONYM RNA-instructed DNA polymerase activity
2007-12-14 Added SYNONYM RT
2007-12-14 Added SYNONYM deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) activity
2007-12-14 Added SYNONYM RNA revertase activity
2007-12-14 Added SYNONYM RNA-dependent DNA polymerase activity
2007-09-06 Added SYNONYM DNA nucleotidyltransferase (RNA-directed) activity
2007-09-06 Added SYNONYM reverse transcriptase activity
2007-09-06 Added SYNONYM revertase activity
2007-09-06 Deleted SYNONYM reverse transcriptase
2007-08-09 Added SYNONYM RNA-directed DNA polymerase, group II intron encoded
2007-08-09 Added SYNONYM RNA-directed DNA polymerase, transposon encoded
2007-08-09 Added SYNONYM reverse transcriptase
2007-08-09 Deleted SYNONYM RNA-directed DNA polymerase, group II intron encoded
2007-08-09 Deleted SYNONYM RNA-directed DNA polymerase, transposon encoded
2007-08-09 Deleted SYNONYM reverse transcriptase
2005-08-10 Added SYNONYM RNA-directed DNA polymerase, group II intron encoded
2005-08-10 Added SYNONYM RNA-directed DNA polymerase, transposon encoded
2004-04-19 Added SYNONYM reverse transcriptase
2004-04-16 Deleted SYNONYM reverse transcriptase
2003-10-27 Added SYNONYM reverse transcriptase
2003-10-27 Added XREF MetaCyc:RNA-DIRECTED-DNA-POLYMERASE-RXN
2003-08-21 Deleted SYNONYM reverse transcriptase
2003-03-19 Updated TERM RNA-directed DNA polymerase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.
2002-02-06 Updated TERM RNA-directed DNA polymerase
2001-04-03 Updated TERM RNA-directed DNA polymerase
2001-03-30 Added XREF EC:2.7.7.49
2001-03-30 Added SYNONYM reverse transcriptase
2001-03-30 Added TERM RNA-directed DNA polymerase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM RNA-directed DNA polymerase activity
2002-02-06 Updated TERM RNA-directed DNA polymerase
2001-04-03 Updated TERM RNA-directed DNA polymerase
2001-03-30 Added TERM RNA-directed DNA polymerase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.
2007-12-14 Added SYNONYM RNA-dependent deoxyribonucleate nucleotidyltransferase activity
2007-12-14 Added SYNONYM RNA-instructed DNA polymerase activity
2007-12-14 Added SYNONYM RT
2007-12-14 Added SYNONYM deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) activity
2007-12-14 Added SYNONYM RNA revertase activity
2007-12-14 Added SYNONYM RNA-dependent DNA polymerase activity
2007-09-06 Added SYNONYM DNA nucleotidyltransferase (RNA-directed) activity
2007-09-06 Added SYNONYM reverse transcriptase activity
2007-09-06 Added SYNONYM revertase activity
2007-09-06 Deleted SYNONYM reverse transcriptase
2007-08-09 Added SYNONYM RNA-directed DNA polymerase, group II intron encoded
2007-08-09 Added SYNONYM RNA-directed DNA polymerase, transposon encoded
2007-08-09 Added SYNONYM reverse transcriptase
2007-08-09 Deleted SYNONYM RNA-directed DNA polymerase, group II intron encoded
2007-08-09 Deleted SYNONYM RNA-directed DNA polymerase, transposon encoded
2007-08-09 Deleted SYNONYM reverse transcriptase
2005-08-10 Added SYNONYM RNA-directed DNA polymerase, group II intron encoded
2005-08-10 Added SYNONYM RNA-directed DNA polymerase, transposon encoded
2004-04-19 Added SYNONYM reverse transcriptase
2004-04-16 Deleted SYNONYM reverse transcriptase
2003-10-27 Added SYNONYM reverse transcriptase
2003-08-21 Deleted SYNONYM reverse transcriptase
2002-11-27 Added DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.
2001-03-30 Added SYNONYM reverse transcriptase

Relationships

Timestamp Action Category Detail
2014-02-07 Added RELATION has part GO:0001171 (reverse transcription)
2013-10-25 Added RELATION part of GO:0006278 (RNA-dependent DNA replication)
2008-04-01 Updated RELATION is a GO:0034061 (DNA polymerase activity)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:RNA-DIRECTED-DNA-POLYMERASE-RXN
2001-03-30 Added XREF EC:2.7.7.49
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
84ms