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GO:0003957 NAD(P)+ transhydrogenase (B-specific) activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to both NAD+ and NADP+.

Term Information

ID GO:0003957
Name NAD(P)+ transhydrogenase (B-specific) activity
Ontology Molecular Function
Definition Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to both NAD+ and NADP+.
Comment

Synonyms

Type Synonym
broad H+-thase
broad NAD transhydrogenase
broad NADH transhydrogenase
broad NADH-NADP-transhydrogenase
broad NADPH-NAD oxidoreductase
broad NADPH-NAD transhydrogenase
exact NADPH:NAD+ oxidoreductase (B-specific)
broad NADPH:NAD+ transhydrogenase
broad nicotinamide adenine dinucleotide (phosphate) transhydrogenase
exact non-energy-linked transhydrogenase activity
broad pyridine nucleotide transferase
exact NAD(P) transhydrogenase (B-specific) activity
broad nicotinamide nucleotide transhydrogenase activity
broad pyridine nucleotide transhydrogenase activity

Cross-references associated with this term:

Database ID
EC 1.6.1.1
MetaCyc PYRNUTRANSHYDROGEN-RXN

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Ancestor Table

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0005215 transporter activity
GO:0022892 substrate-specific transporter activity
GO:0022857 transmembrane transporter activity
GO:0016491 oxidoreductase activity
GO:0016651 oxidoreductase activity, acting on NADH or NADPH
GO:0016652 oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor
GO:0022891 substrate-specific transmembrane transporter activity
GO:0015075 ion transmembrane transporter activity
GO:0008746 NAD(P) transhydrogenase activity
GO:0008324 cation transmembrane transporter activity
GO:0022890 inorganic cation transmembrane transporter activity
GO:0015077 monovalent inorganic cation transmembrane transporter activity
GO:0015078 hydrogen ion transmembrane transporter activity
GO:0003957 NAD(P)+ transhydrogenase (B-specific) activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

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