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GO:0003924 GTPase activity

Catalysis of the reaction: GTP + H2O = GDP + phosphate.

Term Information

ID GO:0003924
Name GTPase activity
Ontology Molecular Function
Definition Catalysis of the reaction: GTP + H2O = GDP + phosphate.
Comment Consider also annotating to the molecular function term 'GTP binding ; GO:0005525'.

Synonyms

Type Synonym
related heterotrimeric G-protein GTPase, beta-subunit
related heterotrimeric G-protein GTPase, gamma-subunit
narrow protein-synthesizing GTPase activity
broad hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement
related heterotrimeric G-protein GTPase, alpha-subunit
narrow heterotrimeric G-protein GTPase activity
narrow dynamin GTPase activity
narrow Rho small monomeric GTPase activity
narrow RHEB small monomeric GTPase activity
narrow ARF small monomeric GTPase activity
narrow Sar small monomeric GTPase activity
narrow tubulin GTPase activity
narrow Ran small monomeric GTPase activity
narrow Rab small monomeric GTPase activity
narrow small monomeric GTPase activity
narrow signal-recognition-particle GTPase activity
narrow protein-synthesizing GTPase activity, termination
narrow protein-synthesizing GTPase activity, initiation
narrow protein-synthesizing GTPase activity, elongation
narrow Ras small monomeric GTPase activity

Cross-references associated with this term:

Database ID
INTERPRO IPR003191
INTERPRO IPR006884
INTERPRO IPR004520
INTERPRO IPR001401
INTERPRO IPR002041
INTERPRO IPR003130
INTERPRO IPR000795
INTERPRO IPR018316
INTERPRO IPR004881
INTERPRO IPR010914
INTERPRO IPR007222
INTERPRO IPR008280
INTERPRO IPR015894
INTERPRO IPR015900

This term can be used instead of these obsolete terms:

GO:0003931 Rho small monomeric GTPase activity (replaced_by GO:0003924)
GO:0003932 SAR small monomeric GTPase activity (replaced_by GO:0003924)
GO:0008547 protein-synthesizing GTPase activity (replaced_by GO:0003924)
GO:0008548 signal-recognition-particle GTPase activity (replaced_by GO:0003924)
GO:0008549 dynamin GTPase activity (replaced_by GO:0003924)
GO:0008550 tubulin GTPase activity (replaced_by GO:0003924)
GO:0008619 RHEB small monomeric GTPase activity (replaced_by GO:0003924)
GO:0016146 protein-synthesizing GTPase activity, initiation (replaced_by GO:0003924)
GO:0016147 protein-synthesizing GTPase activity, elongation (replaced_by GO:0003924)
GO:0016148 protein-synthesizing GTPase activity, termination (replaced_by GO:0003924)
GO:0050800 hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement (replaced_by GO:0003924)
GO:0000263 heterotrimeric G-protein GTPase, alpha-subunit (consider GO:0003924)
GO:0000264 heterotrimeric G-protein GTPase, beta-subunit (consider GO:0003924)
GO:0000265 heterotrimeric G-protein GTPase, gamma-subunit (consider GO:0003924)
GO:0003925 small monomeric GTPase activity (replaced_by GO:0003924)
GO:0003926 ARF small monomeric GTPase activity (replaced_by GO:0003924)
GO:0003927 heterotrimeric G-protein GTPase activity (replaced_by GO:0003924)
GO:0003928 RAB small monomeric GTPase activity (replaced_by GO:0003924)
GO:0003929 RAN small monomeric GTPase activity (replaced_by GO:0003924)
GO:0003930 RAS small monomeric GTPase activity (replaced_by GO:0003924)

Web service: term information

Use this URI template to access this data as a service:

GTerm?id=termID&format=format

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016817 hydrolase activity, acting on acid anhydrides
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0016462 pyrophosphatase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0003924 GTPase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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