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GO:0003917 DNA topoisomerase type I activityCatalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.
Term Information
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| Type | Synonym |
| related | nicking-closing enzyme activity |
| related | omega-protein activity |
| related | relaxing enzyme activity |
| broad | topoisomerase |
| exact | type I topoisomerase activity |
| related | swivelase activity |
| related | untwisting enzyme activity |
| broad | deoxyribonucleate topoisomerase |
| exact | type I DNA topoisomerase activity |
| narrow | DNA topoisomerase I activity |
| Database | ID |
| INTERPRO | IPR001631 |
| INTERPRO | IPR009054 |
| EC | 5.99.1.2 |
| MetaCyc | 5.99.1.2-RXN |
| INTERPRO | IPR000380 |
| INTERPRO | IPR013030 |
| INTERPRO | IPR005733 |
| INTERPRO | IPR018521 |
| INTERPRO | IPR014711 |
| INTERPRO | IPR014727 |
| INTERPRO | IPR013499 |
| INTERPRO | IPR008336 |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | |||||||
![]() | GO:0003824 catalytic activity | ||||||
![]() | ![]() | GO:0005488 binding | |||||
![]() | ![]() | ![]() | GO:0003676 nucleic acid binding | ||||
![]() | ![]() | ![]() | ![]() | GO:0016853 isomerase activity | |||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0003677 DNA binding | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0003916 DNA topoisomerase activity | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0003917 DNA topoisomerase type I activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-21-04-03-45 |