spacer

GO:0003909 DNA ligase activity

Term Information

ID GO:0003909
Name DNA ligase activity
Ontology Molecular Function
Definition Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+.
GONUTS GO:0003909 Wiki Page

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 6.5.1
InterPro IPR016059

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0003909:
Relationship To GO:0003909 Child Term Child Term Name
Is a GO:0003910 DNA ligase (ATP) activity
Is a GO:0003911 DNA ligase (NAD+) activity
Regulates GO:1904875 regulation of DNA ligase activity
Negatively regulates GO:1904876 negative regulation of DNA ligase activity
Positively regulates GO:1904877 positive regulation of DNA ligase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0003909. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0003909 based on the entire annotation set Co-occurrence statistics for GO:0003909 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2016-10-03 Deleted XREF EC:6.5.1.-
2016-10-03 Added XREF EC:6.5.1
2011-04-07 Added RELATION part of GO:0006266 (DNA ligation)
2010-09-24 Deleted DEFINITION Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another; requires an energy source such as ATP or NAD+.
2010-09-24 Added DEFINITION Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+.
2008-05-13 Added DEFINITION Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another; requires an energy source such as ATP or NAD+.
2008-05-12 Deleted DEFINITION Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another; requires an energy source such as ATP or NAD+.
2008-04-01 Updated RELATION is a GO:0016886 (ligase activity, forming phosphoric ester bonds)
2004-03-25 Added DEFINITION Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another; requires an energy source such as ATP or NAD+.
2003-03-19 Updated TERM DNA ligase activity
2002-02-06 Updated TERM DNA ligase
2001-04-03 Updated TERM DNA ligase
2001-03-30 Added XREF EC:6.5.1.-
2001-03-30 Added TERM DNA ligase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM DNA ligase activity
2002-02-06 Updated TERM DNA ligase
2001-04-03 Updated TERM DNA ligase
2001-03-30 Added TERM DNA ligase

Definition/synonyms

Timestamp Action Category Detail
2010-09-24 Deleted DEFINITION Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another; requires an energy source such as ATP or NAD+.
2010-09-24 Added DEFINITION Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+.
2008-05-13 Added DEFINITION Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another; requires an energy source such as ATP or NAD+.
2008-05-12 Deleted DEFINITION Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another; requires an energy source such as ATP or NAD+.
2004-03-25 Added DEFINITION Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another; requires an energy source such as ATP or NAD+.

Relationships

Timestamp Action Category Detail
2011-04-07 Added RELATION part of GO:0006266 (DNA ligation)
2008-04-01 Updated RELATION is a GO:0016886 (ligase activity, forming phosphoric ester bonds)

Cross-references

Timestamp Action Category Detail
2016-10-03 Deleted XREF EC:6.5.1.-
2016-10-03 Added XREF EC:6.5.1
2001-03-30 Added XREF EC:6.5.1.-
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
15ms