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GO:0003899 DNA-directed RNA polymerase activity

Term Information

ID GO:0003899
Name DNA-directed RNA polymerase activity
Ontology Molecular Function
Definition Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
Secondary IDs GO:0000129
GONUTS GO:0003899 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow DNA-directed RNA polymerase III activity
narrow RNA polymerase III activity
exact DNA-dependent RNA polymerase activity
exact RNA nucleotidyltransferase (DNA-directed) activity
related C RNA formation factors
related C ribonucleic acid formation factors
exact DNA-dependent RNA nucleotidyltransferase activity
exact DNA-dependent ribonucleate nucleotidyltransferase activity
exact deoxyribonucleic acid-dependent ribonucleic acid polymerase activity
exact nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) activity
broad transcriptase
narrow DNA-directed RNA polymerase I activity
narrow DNA-directed RNA polymerase II activity
narrow RNA polymerase I activity
narrow RNA polymerase II activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.7.7.6
InterPro IPR000268
InterPro IPR000394
InterPro IPR000722
InterPro IPR000783
InterPro IPR001514
InterPro IPR001529
InterPro IPR002092
InterPro IPR003716
InterPro IPR004519
InterPro IPR004973
InterPro IPR005059
InterPro IPR005571
InterPro IPR005574
InterPro IPR005576
InterPro IPR006110
InterPro IPR006111
InterPro IPR006288
InterPro IPR006591
InterPro IPR006592
InterPro IPR006886
InterPro IPR007025
InterPro IPR007066
InterPro IPR007073
InterPro IPR007075
InterPro IPR007080
InterPro IPR007081
InterPro IPR007083
InterPro IPR007120
InterPro IPR007121
InterPro IPR007641
InterPro IPR007642
InterPro IPR007644
InterPro IPR007645
InterPro IPR007646
InterPro IPR007647
InterPro IPR007811
InterPro IPR007832
InterPro IPR007937
InterPro IPR007984
InterPro IPR008193
InterPro IPR008448
InterPro IPR008771
InterPro IPR008806
InterPro IPR009162
InterPro IPR009668
InterPro IPR009674
InterPro IPR010243
InterPro IPR011260
InterPro IPR011262
InterPro IPR011263
InterPro IPR011773
InterPro IPR012164
InterPro IPR012293
InterPro IPR012754
InterPro IPR012755
InterPro IPR012756
InterPro IPR012757
InterPro IPR012758
InterPro IPR012845
InterPro IPR014724
InterPro IPR015699
InterPro IPR015700
InterPro IPR015712
InterPro IPR019462
InterPro IPR019969
InterPro IPR020609
InterPro IPR020708
InterPro IPR020789
InterPro IPR022842
InterPro IPR022905
InterPro IPR023464
InterPro IPR024075
InterPro IPR028363
InterPro IPR028617
MetaCyc DNA-DIRECTED-RNA-POLYMERASE-RXN
UniProtKB-KW DNA-directed RNA polymerase

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0003900 DNA-directed RNA polymerase I activity REPLACEDBY GO:0003899
GO:0003901 DNA-directed RNA polymerase II activity REPLACEDBY GO:0003899
GO:0003902 DNA-directed RNA polymerase III activity REPLACEDBY GO:0003899

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0003899:
Relationship To GO:0003899 Child Term Child Term Name
Is a GO:0001061 bacterial-type RNA polymerase activity
Is a GO:0001064 single subunit type RNA polymerase activity
Is a GO:0001056 RNA polymerase III activity
Is a GO:0001054 RNA polymerase I activity
Is a GO:0001055 RNA polymerase II activity
Is a GO:0003896 DNA primase activity
Is a GO:0001058 RNA polymerase V activity
Is a GO:0001057 RNA polymerase IV activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0003899. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0003899 based on the entire annotation set Co-occurrence statistics for GO:0003899 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-07-13 Added RELATION part of GO:0032774 (RNA biosynthetic process)
2012-07-13 Deleted RELATION part of GO:0006351 (transcription, DNA-templated)
2010-09-26 Added RELATION part of GO:0006351 (transcription, DNA-templated)
2008-05-13 Added DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2008-04-01 Updated RELATION is a GO:0034062 (RNA polymerase activity)
2008-01-07 Deleted SYNONYM RNA nucleotidyltransferase
2008-01-07 Deleted SYNONYM RNA polymerase
2008-01-07 Deleted SYNONYM RNA transcriptase
2008-01-07 Deleted SYNONYM ribonucleate nucleotidyltransferase
2008-01-07 Deleted SYNONYM ribonucleate polymerase
2008-01-07 Deleted SYNONYM ribonucleic acid nucleotidyltransferase
2008-01-07 Deleted SYNONYM ribonucleic acid polymerase
2008-01-07 Deleted SYNONYM ribonucleic acid transcriptase
2008-01-07 Deleted SYNONYM ribonucleic polymerase
2008-01-07 Deleted SYNONYM ribonucleic transcriptase
2007-12-14 Added SYNONYM C RNA formation factors
2007-12-14 Added SYNONYM C ribonucleic acid formation factors
2007-12-14 Added SYNONYM DNA-dependent RNA nucleotidyltransferase activity
2007-12-14 Added SYNONYM DNA-dependent ribonucleate nucleotidyltransferase activity
2007-12-14 Added SYNONYM RNA nucleotidyltransferase
2007-12-14 Added SYNONYM RNA polymerase
2007-12-14 Added SYNONYM RNA transcriptase
2007-12-14 Added SYNONYM deoxyribonucleic acid-dependent ribonucleic acid polymerase activity
2007-12-14 Added SYNONYM nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) activity
2007-12-14 Added SYNONYM ribonucleate nucleotidyltransferase
2007-12-14 Added SYNONYM ribonucleate polymerase
2007-12-14 Added SYNONYM ribonucleic acid nucleotidyltransferase
2007-12-14 Added SYNONYM ribonucleic acid polymerase
2007-12-14 Added SYNONYM ribonucleic acid transcriptase
2007-12-14 Added SYNONYM ribonucleic polymerase
2007-12-14 Added SYNONYM ribonucleic transcriptase
2007-12-14 Added SYNONYM transcriptase
2007-09-06 Added SYNONYM DNA-dependent RNA polymerase activity
2007-09-06 Added SYNONYM RNA nucleotidyltransferase (DNA-directed) activity
2007-09-06 Added SYNONYM RNA polymerase I activity
2007-09-06 Added SYNONYM RNA polymerase II activity
2007-09-06 Added SYNONYM RNA polymerase III activity
2007-08-09 Added SYNONYM DNA-directed RNA polymerase I activity
2007-08-09 Added SYNONYM DNA-directed RNA polymerase II activity
2007-08-09 Added SYNONYM DNA-directed RNA polymerase III activity
2007-08-09 Deleted SYNONYM DNA-directed RNA polymerase I activity
2007-08-09 Deleted SYNONYM DNA-directed RNA polymerase II activity
2007-08-09 Deleted SYNONYM DNA-directed RNA polymerase III activity
2006-01-24 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2005-08-10 Added SYNONYM DNA-directed RNA polymerase I activity
2005-08-10 Added SYNONYM DNA-directed RNA polymerase II activity
2005-08-10 Added SYNONYM DNA-directed RNA polymerase III activity
2004-03-19 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1), while utilizing a DNA template: i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2003-10-30 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1), while utilizing a DNA template: i. e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2003-10-27 Added XREF MetaCyc:DNA-DIRECTED-RNA-POLYMERASE-RXN
2003-10-24 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1), while utilizing a DNA template: i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2003-04-24 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) while utilizing a DNA template, i. e. the catalysis of DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2003-04-12 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) while utilizing a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2003-03-26 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) while utilizing a DNA template, i.e the catalysis of DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2003-03-19 Updated TERM DNA-directed RNA polymerase activity
2002-11-27 Added DEFINITION Catalysis of DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2002-02-06 Updated TERM DNA-directed RNA polymerase
2001-04-03 Updated TERM DNA-directed RNA polymerase
2001-03-30 Added XREF EC:2.7.7.6
2001-03-30 Added TERM DNA-directed RNA polymerase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM DNA-directed RNA polymerase activity
2002-02-06 Updated TERM DNA-directed RNA polymerase
2001-04-03 Updated TERM DNA-directed RNA polymerase
2001-03-30 Added TERM DNA-directed RNA polymerase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2008-01-07 Deleted SYNONYM RNA nucleotidyltransferase
2008-01-07 Deleted SYNONYM RNA polymerase
2008-01-07 Deleted SYNONYM RNA transcriptase
2008-01-07 Deleted SYNONYM ribonucleate nucleotidyltransferase
2008-01-07 Deleted SYNONYM ribonucleate polymerase
2008-01-07 Deleted SYNONYM ribonucleic acid nucleotidyltransferase
2008-01-07 Deleted SYNONYM ribonucleic acid polymerase
2008-01-07 Deleted SYNONYM ribonucleic acid transcriptase
2008-01-07 Deleted SYNONYM ribonucleic polymerase
2008-01-07 Deleted SYNONYM ribonucleic transcriptase
2007-12-14 Added SYNONYM C RNA formation factors
2007-12-14 Added SYNONYM C ribonucleic acid formation factors
2007-12-14 Added SYNONYM DNA-dependent RNA nucleotidyltransferase activity
2007-12-14 Added SYNONYM DNA-dependent ribonucleate nucleotidyltransferase activity
2007-12-14 Added SYNONYM RNA nucleotidyltransferase
2007-12-14 Added SYNONYM RNA polymerase
2007-12-14 Added SYNONYM RNA transcriptase
2007-12-14 Added SYNONYM deoxyribonucleic acid-dependent ribonucleic acid polymerase activity
2007-12-14 Added SYNONYM nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) activity
2007-12-14 Added SYNONYM ribonucleate nucleotidyltransferase
2007-12-14 Added SYNONYM ribonucleate polymerase
2007-12-14 Added SYNONYM ribonucleic acid nucleotidyltransferase
2007-12-14 Added SYNONYM ribonucleic acid polymerase
2007-12-14 Added SYNONYM ribonucleic acid transcriptase
2007-12-14 Added SYNONYM ribonucleic polymerase
2007-12-14 Added SYNONYM ribonucleic transcriptase
2007-12-14 Added SYNONYM transcriptase
2007-09-06 Added SYNONYM DNA-dependent RNA polymerase activity
2007-09-06 Added SYNONYM RNA nucleotidyltransferase (DNA-directed) activity
2007-09-06 Added SYNONYM RNA polymerase I activity
2007-09-06 Added SYNONYM RNA polymerase II activity
2007-09-06 Added SYNONYM RNA polymerase III activity
2007-08-09 Added SYNONYM DNA-directed RNA polymerase I activity
2007-08-09 Added SYNONYM DNA-directed RNA polymerase II activity
2007-08-09 Added SYNONYM DNA-directed RNA polymerase III activity
2007-08-09 Deleted SYNONYM DNA-directed RNA polymerase I activity
2007-08-09 Deleted SYNONYM DNA-directed RNA polymerase II activity
2007-08-09 Deleted SYNONYM DNA-directed RNA polymerase III activity
2006-01-24 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2005-08-10 Added SYNONYM DNA-directed RNA polymerase I activity
2005-08-10 Added SYNONYM DNA-directed RNA polymerase II activity
2005-08-10 Added SYNONYM DNA-directed RNA polymerase III activity
2004-03-19 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1), while utilizing a DNA template: i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2003-10-30 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1), while utilizing a DNA template: i. e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2003-10-24 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1), while utilizing a DNA template: i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2003-04-24 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) while utilizing a DNA template, i. e. the catalysis of DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2003-04-12 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) while utilizing a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2003-03-26 Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) while utilizing a DNA template, i.e the catalysis of DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2002-11-27 Added DEFINITION Catalysis of DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.

Relationships

Timestamp Action Category Detail
2012-07-13 Added RELATION part of GO:0032774 (RNA biosynthetic process)
2012-07-13 Deleted RELATION part of GO:0006351 (transcription, DNA-templated)
2010-09-26 Added RELATION part of GO:0006351 (transcription, DNA-templated)
2008-04-01 Updated RELATION is a GO:0034062 (RNA polymerase activity)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:DNA-DIRECTED-RNA-POLYMERASE-RXN
2001-03-30 Added XREF EC:2.7.7.6
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