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GO:0003887 DNA-directed DNA polymerase activity

Term Information

ID GO:0003887
Name DNA-directed DNA polymerase activity
Ontology Molecular Function
Definition Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.
Secondary IDs GO:0003888 GO:0003889 GO:0003890 GO:0003891 GO:0003893 GO:0003894 GO:0003895 GO:0008723 GO:0015999 GO:0016000 GO:0016448 GO:0016449 GO:0016450 GO:0016451 GO:0016452 GO:0019984
GONUTS GO:0003887 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow deoxyribonucleic polymerase I
broad duplicase
related sequenase
exact DNA duplicase activity
narrow DNA polymerase I
narrow DNA polymerase II
narrow DNA polymerase III
exact DNA replicase activity
narrow Klenow fragment
narrow Taq DNA polymerase
narrow Taq Pol I
narrow DNA polymerase V activity
narrow DNA polymerase alpha
narrow DNA polymerase beta
narrow DNA polymerase gamma
narrow alpha DNA polymerase activity
narrow beta DNA polymerase activity
narrow delta DNA polymerase activity
narrow epsilon DNA polymerase activity
narrow eta DNA polymerase activity
narrow gamma DNA-directed DNA polymerase activity
narrow iota DNA polymerase activity
narrow kappa DNA polymerase activity
narrow lambda DNA polymerase activity
narrow mu DNA polymerase activity
narrow nu DNA polymerase activity
narrow sigma DNA polymerase activity
narrow theta DNA polymerase activity
narrow zeta DNA polymerase activity
narrow Tca DNA polymerase
exact deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity
exact deoxyribonucleic acid duplicase activity
exact deoxyribonucleic duplicase activity
exact DNA nucleotidyltransferase (DNA-directed) activity
exact DNA-dependent DNA polymerase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.7.7.7
InterPro IPR000201
InterPro IPR000525
InterPro IPR001001
InterPro IPR001098
InterPro IPR001126
InterPro IPR002054
InterPro IPR002298
InterPro IPR003141
InterPro IPR004475
InterPro IPR004578
InterPro IPR004615
InterPro IPR004622
InterPro IPR004868
InterPro IPR006054
InterPro IPR006133
InterPro IPR006134
InterPro IPR006172
InterPro IPR006308
InterPro IPR006309
InterPro IPR007015
InterPro IPR007185
InterPro IPR007459
InterPro IPR009052
InterPro IPR010372
InterPro IPR011149
InterPro IPR011325
InterPro IPR012763
InterPro IPR013617
InterPro IPR013660
InterPro IPR013697
InterPro IPR014382
InterPro IPR014416
InterPro IPR015088
InterPro IPR015199
InterPro IPR015361
InterPro IPR015833
InterPro IPR016265
InterPro IPR016266
InterPro IPR017963
InterPro IPR017964
InterPro IPR018320
InterPro IPR018382
InterPro IPR019760
InterPro IPR021029
InterPro IPR021639
InterPro IPR022634
InterPro IPR022635
InterPro IPR022637
InterPro IPR022754
InterPro IPR022880
InterPro IPR023073
InterPro IPR027249
InterPro IPR029702
InterPro IPR029703
MetaCyc DNA-DIRECTED-DNA-POLYMERASE-RXN
UniProtKB-KW DNA-directed DNA polymerase

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0003887:
Relationship To GO:0003887 Child Term Child Term Name
Regulates GO:1900262 regulation of DNA-directed DNA polymerase activity
Negatively regulates GO:1900263 negative regulation of DNA-directed DNA polymerase activity
Positively regulates GO:1900264 positive regulation of DNA-directed DNA polymerase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0003887. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0003887 based on the entire annotation set Co-occurrence statistics for GO:0003887 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-06-08 Deleted DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and primer.
2014-06-08 Added DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.
2013-10-30 Added RELATION part of GO:0006261 (DNA-dependent DNA replication)
2011-05-03 Deleted XREF EC:2.7.7.-
2008-05-13 Added DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and primer.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and primer.
2008-04-01 Updated RELATION is a GO:0034061 (DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0019984 (sigma DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0016452 (theta DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0016451 (nu DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0016450 (kappa DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0016449 (lambda DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0016448 (mu DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0016000 (iota DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0015999 (eta DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0008723 (DNA polymerase V activity)
2008-03-10 Added SECONDARY GO:0003895 (gamma DNA-directed DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0003894 (zeta DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0003893 (epsilon DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0003891 (delta DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0003890 (beta DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0003889 (alpha DNA polymerase activity)
2008-03-10 Added XREF EC:2.7.7.-
2008-03-10 Added SYNONYM DNA polymerase V activity
2008-03-10 Added SYNONYM DNA polymerase alpha
2008-03-10 Added SYNONYM DNA polymerase beta
2008-03-10 Added SYNONYM DNA polymerase gamma
2008-03-10 Added SYNONYM alpha DNA polymerase activity
2008-03-10 Added SYNONYM beta DNA polymerase activity
2008-03-10 Added SYNONYM delta DNA polymerase activity
2008-03-10 Added SYNONYM epsilon DNA polymerase activity
2008-03-10 Added SYNONYM eta DNA polymerase activity
2008-03-10 Added SYNONYM gamma DNA-directed DNA polymerase activity
2008-03-10 Added SYNONYM iota DNA polymerase activity
2008-03-10 Added SYNONYM kappa DNA polymerase activity
2008-03-10 Added SYNONYM lambda DNA polymerase activity
2008-03-10 Added SYNONYM mu DNA polymerase activity
2008-03-10 Added SYNONYM nu DNA polymerase activity
2008-03-10 Added SYNONYM sigma DNA polymerase activity
2008-03-10 Added SYNONYM theta DNA polymerase activity
2008-03-10 Added SYNONYM zeta DNA polymerase activity
2008-01-07 Deleted SYNONYM DNA nucleotidyltransferase activity
2008-01-07 Deleted SYNONYM DNA polymerase
2008-01-07 Deleted SYNONYM deoxynucleate polymerase activity
2008-01-07 Deleted SYNONYM deoxyribonucleate nucleotidyltransferase activity
2008-01-07 Deleted SYNONYM deoxyribonucleic acid polymerase
2008-01-07 Deleted SYNONYM deoxyribonucleic polymerase
2007-12-14 Added SYNONYM DNA polymerase I
2007-12-14 Added SYNONYM DNA polymerase II
2007-12-14 Added SYNONYM DNA polymerase III
2007-12-14 Added SYNONYM DNA replicase activity
2007-12-14 Added SYNONYM Klenow fragment
2007-12-14 Added SYNONYM Taq DNA polymerase
2007-12-14 Added SYNONYM Taq Pol I
2007-12-14 Added SYNONYM Tca DNA polymerase
2007-12-14 Added SYNONYM deoxynucleate polymerase activity
2007-12-14 Added SYNONYM deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity
2007-12-14 Added SYNONYM deoxyribonucleate nucleotidyltransferase activity
2007-12-14 Added SYNONYM deoxyribonucleic acid duplicase activity
2007-12-14 Added SYNONYM deoxyribonucleic acid polymerase
2007-12-14 Added SYNONYM deoxyribonucleic duplicase activity
2007-12-14 Added SYNONYM deoxyribonucleic polymerase
2007-12-14 Added SYNONYM deoxyribonucleic polymerase I
2007-12-14 Added SYNONYM duplicase
2007-12-14 Added SYNONYM sequenase
2007-12-14 Added SYNONYM DNA duplicase activity
2007-12-14 Added SYNONYM DNA nucleotidyltransferase activity
2007-12-14 Added SYNONYM DNA polymerase
2007-11-27 Updated DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and primer.
2007-09-06 Added SYNONYM DNA nucleotidyltransferase (DNA-directed) activity
2007-09-06 Added SYNONYM DNA-dependent DNA polymerase activity
2006-01-24 Updated DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template or primer.
2003-10-27 Added XREF MetaCyc:DNA-DIRECTED-DNA-POLYMERASE-RXN
2003-03-26 Updated DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1) in the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template or primer.
2003-03-19 Updated TERM DNA-directed DNA polymerase activity
2002-11-27 Updated DEFINITION Enzymes that catalyze the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template or primer.
2002-02-06 Updated TERM DNA-directed DNA polymerase
2001-08-06 Added DEFINITION Enzymes that catalyse the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template or primer.
2001-04-03 Updated TERM DNA-directed DNA polymerase
2001-03-30 Added XREF EC:2.7.7.7
2001-03-30 Added TERM DNA-directed DNA polymerase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM DNA-directed DNA polymerase activity
2002-02-06 Updated TERM DNA-directed DNA polymerase
2001-04-03 Updated TERM DNA-directed DNA polymerase
2001-03-30 Added TERM DNA-directed DNA polymerase

Definition/synonyms

Timestamp Action Category Detail
2014-06-08 Deleted DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and primer.
2014-06-08 Added DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.
2008-05-13 Added DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and primer.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and primer.
2008-03-10 Added SYNONYM DNA polymerase V activity
2008-03-10 Added SYNONYM DNA polymerase alpha
2008-03-10 Added SYNONYM DNA polymerase beta
2008-03-10 Added SYNONYM DNA polymerase gamma
2008-03-10 Added SYNONYM alpha DNA polymerase activity
2008-03-10 Added SYNONYM beta DNA polymerase activity
2008-03-10 Added SYNONYM delta DNA polymerase activity
2008-03-10 Added SYNONYM epsilon DNA polymerase activity
2008-03-10 Added SYNONYM eta DNA polymerase activity
2008-03-10 Added SYNONYM gamma DNA-directed DNA polymerase activity
2008-03-10 Added SYNONYM iota DNA polymerase activity
2008-03-10 Added SYNONYM kappa DNA polymerase activity
2008-03-10 Added SYNONYM lambda DNA polymerase activity
2008-03-10 Added SYNONYM mu DNA polymerase activity
2008-03-10 Added SYNONYM nu DNA polymerase activity
2008-03-10 Added SYNONYM sigma DNA polymerase activity
2008-03-10 Added SYNONYM theta DNA polymerase activity
2008-03-10 Added SYNONYM zeta DNA polymerase activity
2008-01-07 Deleted SYNONYM DNA nucleotidyltransferase activity
2008-01-07 Deleted SYNONYM DNA polymerase
2008-01-07 Deleted SYNONYM deoxynucleate polymerase activity
2008-01-07 Deleted SYNONYM deoxyribonucleate nucleotidyltransferase activity
2008-01-07 Deleted SYNONYM deoxyribonucleic acid polymerase
2008-01-07 Deleted SYNONYM deoxyribonucleic polymerase
2007-12-14 Added SYNONYM DNA polymerase I
2007-12-14 Added SYNONYM DNA polymerase II
2007-12-14 Added SYNONYM DNA polymerase III
2007-12-14 Added SYNONYM DNA replicase activity
2007-12-14 Added SYNONYM Klenow fragment
2007-12-14 Added SYNONYM Taq DNA polymerase
2007-12-14 Added SYNONYM Taq Pol I
2007-12-14 Added SYNONYM Tca DNA polymerase
2007-12-14 Added SYNONYM deoxynucleate polymerase activity
2007-12-14 Added SYNONYM deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity
2007-12-14 Added SYNONYM deoxyribonucleate nucleotidyltransferase activity
2007-12-14 Added SYNONYM deoxyribonucleic acid duplicase activity
2007-12-14 Added SYNONYM deoxyribonucleic acid polymerase
2007-12-14 Added SYNONYM deoxyribonucleic duplicase activity
2007-12-14 Added SYNONYM deoxyribonucleic polymerase
2007-12-14 Added SYNONYM deoxyribonucleic polymerase I
2007-12-14 Added SYNONYM duplicase
2007-12-14 Added SYNONYM sequenase
2007-12-14 Added SYNONYM DNA duplicase activity
2007-12-14 Added SYNONYM DNA nucleotidyltransferase activity
2007-12-14 Added SYNONYM DNA polymerase
2007-11-27 Updated DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and primer.
2007-09-06 Added SYNONYM DNA nucleotidyltransferase (DNA-directed) activity
2007-09-06 Added SYNONYM DNA-dependent DNA polymerase activity
2006-01-24 Updated DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template or primer.
2003-03-26 Updated DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1) in the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template or primer.
2002-11-27 Updated DEFINITION Enzymes that catalyze the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template or primer.
2001-08-06 Added DEFINITION Enzymes that catalyse the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template or primer.

Relationships

Timestamp Action Category Detail
2013-10-30 Added RELATION part of GO:0006261 (DNA-dependent DNA replication)
2008-04-01 Updated RELATION is a GO:0034061 (DNA polymerase activity)

Cross-references

Timestamp Action Category Detail
2011-05-03 Deleted XREF EC:2.7.7.-
2008-03-10 Added XREF EC:2.7.7.-
2003-10-27 Added XREF MetaCyc:DNA-DIRECTED-DNA-POLYMERASE-RXN
2001-03-30 Added XREF EC:2.7.7.7

Other

Timestamp Action Category Detail
2008-03-10 Added SECONDARY GO:0019984 (sigma DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0016452 (theta DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0016451 (nu DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0016450 (kappa DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0016449 (lambda DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0016448 (mu DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0016000 (iota DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0015999 (eta DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0008723 (DNA polymerase V activity)
2008-03-10 Added SECONDARY GO:0003895 (gamma DNA-directed DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0003894 (zeta DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0003893 (epsilon DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0003891 (delta DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0003890 (beta DNA polymerase activity)
2008-03-10 Added SECONDARY GO:0003889 (alpha DNA polymerase activity)
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