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GO:0003886 DNA (cytosine-5-)-methyltransferase activity

Term Information

ID GO:0003886
Name DNA (cytosine-5-)-methyltransferase activity
Ontology Molecular Function
Definition Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
Comment Note that EC:2.1.1.73 was deleted from EC as the reaction is performed by DNA (cytosine-5-)-methyltransferase (EC:2.1.1.37).
Secondary IDs GO:0008326
GONUTS GO:0003886 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow site-specific DNA-methyltransferase (cytosine-specific) activity
exact deoxyribonucleic acid (cytosine-5-)-methyltransferase activity
broad deoxyribonucleic methylase activity
related methylphosphotriester-DNA methyltransferase activity
related modification methylase activity
related restriction-modification system activity
related type II DNA methylase activity
exact DNA cytosine C5 methylase activity
exact S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase activity
exact DNA 5-cytosine methylase activity
exact DNA cytosine C(5) methylase activity
broad DNA cytosine methylase activity
exact DNA-cytosine 5-methylase activity
broad DNA-cytosine methyltransferase activity
exact cytosine 5-methyltransferase activity
broad cytosine DNA methylase activity
broad cytosine DNA methyltransferase activity
exact cytosine-specific DNA methyltransferase activity
exact deoxyribonucleic (cytosine-5-)-methyltransferase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000461 GO:0006306 DNA methylation never_in_taxon 4930 Saccharomyces
GOTAX:0000463 GO:0006306 DNA methylation never_in_taxon 4895 Schizosaccharomyces
More information on taxon constraints in GO is available here

Cross-references

Database ID
EC 2.1.1.37
InterPro IPR017198
MetaCyc 2.1.1.73-RXN

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0003886:
Relationship To GO:0003886 Child Term Child Term Name
Is a GO:0051718 DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
Is a GO:0051719 DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates
Is a GO:0051720 DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0003886. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0003886 based on the entire annotation set Co-occurrence statistics for GO:0003886 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-10-28 Deleted SYNONYM DNA cytosine c5 methylase activity
2010-07-16 Added RELATION part of GO:0090116 (C-5 methylation of cytosine)
2009-05-21 Deleted XREF MetaCyc:DNA-(CYTOSINE-5-)-METHYLTRANSFERASE-RXN
2008-05-13 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
2008-05-13 Added SYNONYM site-specific DNA-methyltransferase (cytosine-specific) activity
2008-05-13 Added XREF MetaCyc:2.1.1.73-RXN
2008-05-13 Added SECONDARY GO:0008326 (site-specific DNA-methyltransferase (cytosine-specific) activity)
2008-05-12 Deleted DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
2008-04-01 Updated RELATION is a GO:0009008 (DNA-methyltransferase activity)
2008-04-01 Updated RELATION is a GO:0008757 (S-adenosylmethionine-dependent methyltransferase activity)
2007-12-14 Added SYNONYM DNA cytosine C5 methylase activity
2007-12-14 Added SYNONYM DNA cytosine c5 methylase activity
2007-12-14 Added SYNONYM S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase activity
2007-09-06 Added SYNONYM cytosine-specific DNA methyltransferase activity
2007-09-06 Added SYNONYM deoxyribonucleic (cytosine-5-)-methyltransferase activity
2007-09-06 Added SYNONYM deoxyribonucleic acid (cytosine-5-)-methyltransferase activity
2007-09-06 Added SYNONYM deoxyribonucleic methylase activity
2007-09-06 Added SYNONYM methylphosphotriester-DNA methyltransferase activity
2007-09-06 Added SYNONYM modification methylase activity
2007-09-06 Added SYNONYM restriction-modification system activity
2007-09-06 Added SYNONYM type II DNA methylase activity
2007-09-06 Added SYNONYM DNA 5-cytosine methylase activity
2007-09-06 Added SYNONYM DNA cytosine C(5) methylase activity
2007-09-06 Added SYNONYM DNA cytosine methylase activity
2007-09-06 Added SYNONYM DNA-cytosine 5-methylase activity
2007-09-06 Added SYNONYM DNA-cytosine methyltransferase activity
2007-09-06 Added SYNONYM cytosine 5-methyltransferase activity
2007-09-06 Added SYNONYM cytosine DNA methylase activity
2007-09-06 Added SYNONYM cytosine DNA methyltransferase activity
2005-12-14 Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
2003-10-27 Added XREF MetaCyc:DNA-(CYTOSINE-5-)-METHYLTRANSFERASE-RXN
2003-03-19 Updated TERM DNA (cytosine-5-)-methyltransferase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
2002-02-06 Updated TERM DNA (cytosine-5-)-methyltransferase
2001-04-03 Updated TERM DNA (cytosine-5-)-methyltransferase
2001-03-30 Added XREF EC:2.1.1.37
2001-03-30 Added TERM DNA (cytosine-5-)-methyltransferase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM DNA (cytosine-5-)-methyltransferase activity
2002-02-06 Updated TERM DNA (cytosine-5-)-methyltransferase
2001-04-03 Updated TERM DNA (cytosine-5-)-methyltransferase
2001-03-30 Added TERM DNA (cytosine-5-)-methyltransferase

Definition/synonyms

Timestamp Action Category Detail
2011-10-28 Deleted SYNONYM DNA cytosine c5 methylase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
2008-05-13 Added SYNONYM site-specific DNA-methyltransferase (cytosine-specific) activity
2008-05-12 Deleted DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
2007-12-14 Added SYNONYM DNA cytosine C5 methylase activity
2007-12-14 Added SYNONYM DNA cytosine c5 methylase activity
2007-12-14 Added SYNONYM S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase activity
2007-09-06 Added SYNONYM cytosine-specific DNA methyltransferase activity
2007-09-06 Added SYNONYM deoxyribonucleic (cytosine-5-)-methyltransferase activity
2007-09-06 Added SYNONYM deoxyribonucleic acid (cytosine-5-)-methyltransferase activity
2007-09-06 Added SYNONYM deoxyribonucleic methylase activity
2007-09-06 Added SYNONYM methylphosphotriester-DNA methyltransferase activity
2007-09-06 Added SYNONYM modification methylase activity
2007-09-06 Added SYNONYM restriction-modification system activity
2007-09-06 Added SYNONYM type II DNA methylase activity
2007-09-06 Added SYNONYM DNA 5-cytosine methylase activity
2007-09-06 Added SYNONYM DNA cytosine C(5) methylase activity
2007-09-06 Added SYNONYM DNA cytosine methylase activity
2007-09-06 Added SYNONYM DNA-cytosine 5-methylase activity
2007-09-06 Added SYNONYM DNA-cytosine methyltransferase activity
2007-09-06 Added SYNONYM cytosine 5-methyltransferase activity
2007-09-06 Added SYNONYM cytosine DNA methylase activity
2007-09-06 Added SYNONYM cytosine DNA methyltransferase activity
2005-12-14 Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
2002-11-27 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.

Relationships

Timestamp Action Category Detail
2010-07-16 Added RELATION part of GO:0090116 (C-5 methylation of cytosine)
2008-04-01 Updated RELATION is a GO:0009008 (DNA-methyltransferase activity)
2008-04-01 Updated RELATION is a GO:0008757 (S-adenosylmethionine-dependent methyltransferase activity)

Cross-references

Timestamp Action Category Detail
2009-05-21 Deleted XREF MetaCyc:DNA-(CYTOSINE-5-)-METHYLTRANSFERASE-RXN
2008-05-13 Added XREF MetaCyc:2.1.1.73-RXN
2003-10-27 Added XREF MetaCyc:DNA-(CYTOSINE-5-)-METHYLTRANSFERASE-RXN
2001-03-30 Added XREF EC:2.1.1.37

Other

Timestamp Action Category Detail
2008-05-13 Added SECONDARY GO:0008326 (site-specific DNA-methyltransferase (cytosine-specific) activity)
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