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GO:0003878 ATP citrate synthase activity

Catalysis of the reaction: ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA.

Term Information

ID GO:0003878
Name ATP citrate synthase activity
Ontology Molecular Function
Definition Catalysis of the reaction: ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA.
Comment Note that this function was formerly EC:4.1.3.8.

Synonyms

Type Synonym
exact ATP-citrate (pro-S-)-lyase activity
related citric cleavage enzyme activity
exact ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity
exact ATP citrate (pro-S)-lyase activity
exact acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity
exact ATP-citric lyase activity
exact acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)
related acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]
related ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)
exact citrate-ATP lyase activity
related citrate cleavage enzyme activity
exact adenosine triphosphate citrate lyase activity
exact ATP-citrate (pro-S)-lyase activity

Cross-references associated with this term:

Database ID
EC 2.3.3.8
MetaCyc ATP-CITRATE-PRO-S--LYASE-RXN
MetaCyc PWY-5172
INTERPRO IPR017440
INTERPRO IPR014608

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Ancestor Table

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016746 transferase activity, transferring acyl groups
GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
GO:0003878 ATP citrate synthase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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