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GO:0003870 5-aminolevulinate synthase activity

Term Information

ID GO:0003870
Name 5-aminolevulinate synthase activity
Ontology Molecular Function
Definition Catalysis of the reaction: glycine + H(+) + succinyl-CoA = 5-aminolevulinate + CO(2) + CoA.
GONUTS GO:0003870 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact 5-aminolevulinic acid synthase activity
exact ALA synthase activity
exact delta-ALA synthetase activity
exact delta-aminolevulinate synthase activity
exact ALAS activity
exact 5-aminolevulinic acid synthetase activity
exact 5-aminolevulinate synthetase activity
exact succinyl-CoA:glycine C-succinyltransferase (decarboxylating)
exact delta-aminolevulinic synthetase activity
exact delta-aminolevulinic acid synthetase activity
exact delta-aminolevulinic acid synthase activity
exact delta-aminolevulinate synthetase activity
exact aminolevulinic synthetase activity
exact aminolevulinic acid synthetase activity
exact aminolevulinic acid synthase activity
exact aminolevulinate synthetase activity
exact aminolevulinate synthase activity
exact alpha-aminolevulinic acid synthase activity
exact ALA synthetase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.3.1.37
InterPro IPR010961
InterPro IPR015118
KEGG R00830
MetaCyc 5-AMINOLEVULINIC-ACID-SYNTHASE-RXN
RHEA 12924

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0003870:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0003870. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0003870 based on the entire annotation set Co-occurrence statistics for GO:0003870 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2.
2010-10-11 Added DEFINITION Catalysis of the reaction: glycine + H(+) + succinyl-CoA = 5-aminolevulinate + CO(2) + CoA.
2010-10-11 Added XREF RHEA:12924
2010-10-11 Added XREF KEGG:R00830
2008-05-13 Added DEFINITION Catalysis of the reaction: succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2.
2008-04-01 Updated RELATION is a GO:0016749 (N-succinyltransferase activity)
2007-11-08 Added SYNONYM 5-aminolevulinate synthetase activity
2007-11-08 Added SYNONYM 5-aminolevulinic acid synthetase activity
2007-11-08 Added SYNONYM ALA synthase activity
2007-11-08 Added SYNONYM ALA synthetase activity
2007-11-08 Added SYNONYM alpha-aminolevulinic acid synthase activity
2007-11-08 Added SYNONYM aminolevulinate synthase activity
2007-11-08 Added SYNONYM aminolevulinate synthetase activity
2007-11-08 Added SYNONYM aminolevulinic acid synthase activity
2007-11-08 Added SYNONYM aminolevulinic acid synthetase activity
2007-11-08 Added SYNONYM aminolevulinic synthetase activity
2007-11-08 Added SYNONYM delta-aminolevulinate synthetase activity
2007-11-08 Added SYNONYM delta-aminolevulinic acid synthase activity
2007-11-08 Added SYNONYM delta-aminolevulinic acid synthetase activity
2007-11-08 Added SYNONYM delta-aminolevulinic synthetase activity
2007-11-08 Added SYNONYM succinyl-CoA:glycine C-succinyltransferase (decarboxylating)
2007-09-06 Added SYNONYM 5-aminolevulinic acid synthase activity
2007-09-06 Added SYNONYM ALAS activity
2007-09-06 Added SYNONYM delta-ALA synthetase activity
2007-09-06 Added SYNONYM delta-aminolevulinate synthase activity
2003-10-27 Added XREF MetaCyc:5-AMINOLEVULINIC-ACID-SYNTHASE-RXN
2003-10-23 Updated DEFINITION Catalysis of the reaction: succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2.
2003-03-19 Updated TERM 5-aminolevulinate synthase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: succinyl-CoA + glycine = 5-aminolevulinate + CoA + carbon dioxide.
2002-02-06 Updated TERM 5-aminolevulinate synthase
2001-04-03 Updated TERM 5-aminolevulinate synthase
2001-03-30 Added XREF EC:2.3.1.37
2001-03-30 Added TERM 5-aminolevulinate synthase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM 5-aminolevulinate synthase activity
2002-02-06 Updated TERM 5-aminolevulinate synthase
2001-04-03 Updated TERM 5-aminolevulinate synthase
2001-03-30 Added TERM 5-aminolevulinate synthase

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2.
2010-10-11 Added DEFINITION Catalysis of the reaction: glycine + H(+) + succinyl-CoA = 5-aminolevulinate + CO(2) + CoA.
2008-05-13 Added DEFINITION Catalysis of the reaction: succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2.
2007-11-08 Added SYNONYM 5-aminolevulinate synthetase activity
2007-11-08 Added SYNONYM 5-aminolevulinic acid synthetase activity
2007-11-08 Added SYNONYM ALA synthase activity
2007-11-08 Added SYNONYM ALA synthetase activity
2007-11-08 Added SYNONYM alpha-aminolevulinic acid synthase activity
2007-11-08 Added SYNONYM aminolevulinate synthase activity
2007-11-08 Added SYNONYM aminolevulinate synthetase activity
2007-11-08 Added SYNONYM aminolevulinic acid synthase activity
2007-11-08 Added SYNONYM aminolevulinic acid synthetase activity
2007-11-08 Added SYNONYM aminolevulinic synthetase activity
2007-11-08 Added SYNONYM delta-aminolevulinate synthetase activity
2007-11-08 Added SYNONYM delta-aminolevulinic acid synthase activity
2007-11-08 Added SYNONYM delta-aminolevulinic acid synthetase activity
2007-11-08 Added SYNONYM delta-aminolevulinic synthetase activity
2007-11-08 Added SYNONYM succinyl-CoA:glycine C-succinyltransferase (decarboxylating)
2007-09-06 Added SYNONYM 5-aminolevulinic acid synthase activity
2007-09-06 Added SYNONYM ALAS activity
2007-09-06 Added SYNONYM delta-ALA synthetase activity
2007-09-06 Added SYNONYM delta-aminolevulinate synthase activity
2003-10-23 Updated DEFINITION Catalysis of the reaction: succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2.
2002-11-27 Added DEFINITION Catalysis of the reaction: succinyl-CoA + glycine = 5-aminolevulinate + CoA + carbon dioxide.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016749 (N-succinyltransferase activity)

Cross-references

Timestamp Action Category Detail
2010-10-11 Added XREF RHEA:12924
2010-10-11 Added XREF KEGG:R00830
2003-10-27 Added XREF MetaCyc:5-AMINOLEVULINIC-ACID-SYNTHASE-RXN
2001-03-30 Added XREF EC:2.3.1.37
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