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GO:0003848 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity

Term Information

ID GO:0003848
Name 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity
Ontology Molecular Function
Definition Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP = (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate + AMP + 2 H(+).
GONUTS GO:0003848 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity
exact 7,8-dihydro-6-hydroxymethylpterin diphosphokinase activity
exact 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase activity
exact 6-hydroxymethyl-7,8-dihydropterin diphosphokinase activity
exact 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase activity
exact 7,8-dihydroxymethylpterin-pyrophosphokinase activity
exact ATP:2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine 6'-diphosphotransferase activity
exact H2-pteridine-CH2OH pyrophosphokinase activity
related HPPK
exact hydroxymethyldihydropteridine pyrophosphokinase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.7.6.3
InterPro IPR000550
InterPro IPR016261
InterPro IPR027510
KEGG R03503
MetaCyc H2PTERIDINEPYROPHOSPHOKIN-RXN
RHEA 11415

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0003848:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0003848. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0003848 based on the entire annotation set Co-occurrence statistics for GO:0003848 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: ATP + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine = AMP + 2-amino-7,8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine.
2010-10-11 Added DEFINITION Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP = (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate + AMP + 2 H(+).
2010-10-11 Added XREF KEGG:R03503
2010-10-11 Added XREF RHEA:11415
2008-06-20 Deleted RELATION is a GO:0016301 (kinase activity)
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine = AMP + 2-amino-7,8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine = AMP + 2-amino-7,8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine.
2008-04-01 Updated RELATION is a GO:0016778 (diphosphotransferase activity)
2008-04-01 Updated RELATION is a GO:0016301 (kinase activity)
2007-11-08 Added SYNONYM 7,8-dihydroxymethylpterin-pyrophosphokinase activity
2007-11-08 Added SYNONYM ATP:2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine 6'-diphosphotransferase activity
2007-11-08 Added SYNONYM H2-pteridine-CH2OH pyrophosphokinase activity
2007-11-08 Added SYNONYM HPPK
2007-11-08 Added SYNONYM hydroxymethyldihydropteridine pyrophosphokinase activity
2007-09-06 Added SYNONYM 6-hydroxymethyl-7,8-dihydropterin diphosphokinase activity
2007-09-06 Added SYNONYM 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase activity
2007-09-06 Added SYNONYM 7,8-dihydro-6-hydroxymethylpterin diphosphokinase activity
2007-09-06 Added SYNONYM 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase activity
2007-08-09 Added SYNONYM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity
2007-08-09 Deleted SYNONYM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity
2004-04-19 Added SYNONYM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity
2004-04-16 Deleted SYNONYM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity
2003-10-27 Added SYNONYM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity
2003-10-27 Added XREF MetaCyc:H2PTERIDINEPYROPHOSPHOKIN-RXN
2003-09-09 Updated TERM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity
2003-03-19 Updated TERM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine = AMP + 2-amino-7,8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine.
2002-02-06 Updated TERM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
2001-04-03 Updated TERM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
2001-03-30 Added XREF EC:2.7.6.3
2001-03-30 Added TERM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase

Term

Timestamp Action Category Detail
2003-09-09 Updated TERM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity
2003-03-19 Updated TERM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity
2002-02-06 Updated TERM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
2001-04-03 Updated TERM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
2001-03-30 Added TERM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase

Definition/synonyms

Timestamp Action Category Detail
2010-10-11 Deleted DEFINITION Catalysis of the reaction: ATP + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine = AMP + 2-amino-7,8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine.
2010-10-11 Added DEFINITION Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP = (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate + AMP + 2 H(+).
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine = AMP + 2-amino-7,8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine = AMP + 2-amino-7,8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine.
2007-11-08 Added SYNONYM 7,8-dihydroxymethylpterin-pyrophosphokinase activity
2007-11-08 Added SYNONYM ATP:2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine 6'-diphosphotransferase activity
2007-11-08 Added SYNONYM H2-pteridine-CH2OH pyrophosphokinase activity
2007-11-08 Added SYNONYM HPPK
2007-11-08 Added SYNONYM hydroxymethyldihydropteridine pyrophosphokinase activity
2007-09-06 Added SYNONYM 6-hydroxymethyl-7,8-dihydropterin diphosphokinase activity
2007-09-06 Added SYNONYM 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase activity
2007-09-06 Added SYNONYM 7,8-dihydro-6-hydroxymethylpterin diphosphokinase activity
2007-09-06 Added SYNONYM 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase activity
2007-08-09 Added SYNONYM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity
2007-08-09 Deleted SYNONYM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity
2004-04-19 Added SYNONYM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity
2004-04-16 Deleted SYNONYM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity
2003-10-27 Added SYNONYM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine = AMP + 2-amino-7,8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine.

Relationships

Timestamp Action Category Detail
2008-06-20 Deleted RELATION is a GO:0016301 (kinase activity)
2008-04-01 Updated RELATION is a GO:0016778 (diphosphotransferase activity)
2008-04-01 Updated RELATION is a GO:0016301 (kinase activity)

Cross-references

Timestamp Action Category Detail
2010-10-11 Added XREF KEGG:R03503
2010-10-11 Added XREF RHEA:11415
2003-10-27 Added XREF MetaCyc:H2PTERIDINEPYROPHOSPHOKIN-RXN
2001-03-30 Added XREF EC:2.7.6.3
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