spacer

GO:0003824 catalytic activity

Term Information

ID GO:0003824
Name catalytic activity
Ontology Molecular Function
Definition Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GONUTS GO:0003824 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact enzyme activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_pir462
goslim_plant100

Cross-references

Database ID
InterPro IPR000183
InterPro IPR000310
InterPro IPR000326
InterPro IPR000385
InterPro IPR000391
InterPro IPR000486
InterPro IPR000581
InterPro IPR000594
InterPro IPR000627
InterPro IPR000639
InterPro IPR000669
InterPro IPR000672
InterPro IPR000728
InterPro IPR000734
InterPro IPR000794
InterPro IPR000845
InterPro IPR000868
InterPro IPR000873
InterPro IPR000891
InterPro IPR001045
InterPro IPR001093
InterPro IPR001144
InterPro IPR001150
InterPro IPR001228
InterPro IPR001330
InterPro IPR001345
InterPro IPR001354
InterPro IPR001509
InterPro IPR001544
InterPro IPR001736
InterPro IPR001753
InterPro IPR001830
InterPro IPR001932
InterPro IPR002500
InterPro IPR002529
InterPro IPR002591
InterPro IPR003094
InterPro IPR003337
InterPro IPR003382
InterPro IPR003541
InterPro IPR003664
InterPro IPR003673
InterPro IPR003692
InterPro IPR003696
InterPro IPR003702
InterPro IPR003719
InterPro IPR004013
InterPro IPR004113
InterPro IPR004184
InterPro IPR004232
InterPro IPR004300
InterPro IPR004456
InterPro IPR004459
InterPro IPR004821
InterPro IPR004838
InterPro IPR005000
InterPro IPR005195
InterPro IPR005196
InterPro IPR005302
InterPro IPR005476
InterPro IPR005481
InterPro IPR005766
InterPro IPR005809
InterPro IPR005810
InterPro IPR005811
InterPro IPR005860
InterPro IPR005955
InterPro IPR005966
InterPro IPR006046
InterPro IPR006047
InterPro IPR006048
InterPro IPR006124
InterPro IPR006379
InterPro IPR006589
InterPro IPR006638
InterPro IPR006992
InterPro IPR007044
InterPro IPR007197
InterPro IPR007439
InterPro IPR008262
InterPro IPR008286
InterPro IPR008918
InterPro IPR008928
InterPro IPR008948
InterPro IPR008960
InterPro IPR008977
InterPro IPR009003
InterPro IPR009006
InterPro IPR009014
InterPro IPR009097
InterPro IPR010663
InterPro IPR010997
InterPro IPR011013
InterPro IPR011034
InterPro IPR011039
InterPro IPR011041
InterPro IPR011060
InterPro IPR011076
InterPro IPR011146
InterPro IPR011234
InterPro IPR011249
InterPro IPR011254
InterPro IPR011257
InterPro IPR011330
InterPro IPR011639
InterPro IPR011698
InterPro IPR011766
InterPro IPR011870
InterPro IPR012341
InterPro IPR012810
InterPro IPR013049
InterPro IPR013482
InterPro IPR013670
InterPro IPR013785
InterPro IPR013792
InterPro IPR013815
InterPro IPR013848
InterPro IPR014048
InterPro IPR014224
InterPro IPR014718
InterPro IPR014746
InterPro IPR015179
InterPro IPR015421
InterPro IPR015422
InterPro IPR015527
InterPro IPR015813
InterPro IPR015902
InterPro IPR015955
InterPro IPR016036
InterPro IPR016038
InterPro IPR016039
InterPro IPR016099
InterPro IPR016100
InterPro IPR016164
InterPro IPR016166
InterPro IPR016167
InterPro IPR016176
InterPro IPR016188
InterPro IPR016193
InterPro IPR016195
InterPro IPR017440
InterPro IPR017849
InterPro IPR017850
InterPro IPR018294
InterPro IPR018300
InterPro IPR018376
InterPro IPR018523
InterPro IPR018934
InterPro IPR020045
InterPro IPR020557
InterPro IPR020558
InterPro IPR020630
InterPro IPR020631
InterPro IPR020867
InterPro IPR022494
InterPro IPR022643
InterPro IPR022644
InterPro IPR023546
InterPro IPR026347
UniProtKB-KW Allosteric enzyme
UniProtKB-KW Bacteriolytic enzyme
UniProtKB-KW Multifunctional enzyme
Wikipedia Enzyme

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0003824:
Relationship To GO:0003824 Child Term Child Term Name
Is a GO:0043336 site-specific telomere resolvase activity
Is a GO:0046905 phytoene synthase activity
Is a GO:0009975 cyclase activity
Is a GO:0032451 demethylase activity
Is a GO:0004133 glycogen debranching enzyme activity
Is a GO:0008265 Mo-molybdopterin cofactor sulfurase activity
Is a GO:0008907 integrase activity
Is a GO:0008987 quinolinate synthetase A activity
Is a GO:0004803 transposase activity
Is a GO:0043364 catalysis of free radical formation
Is a GO:0008641 small protein activating enzyme activity
Is a GO:0000150 recombinase activity
Is a GO:0009009 site-specific recombinase activity
Is a GO:0016217 N-ethylammeline chlorohydrolase activity
Is a GO:0016491 oxidoreductase activity
Is a GO:0019239 deaminase activity
Is a GO:0046572 versicolorin B synthase activity
Is a GO:0016740 transferase activity
Is a GO:0016787 hydrolase activity
Is a GO:0016829 lyase activity
Is a GO:0016853 isomerase activity
Is a GO:0016874 ligase activity
Regulates GO:0030234 enzyme regulator activity
Positively regulates GO:0043085 positive regulation of catalytic activity
Negatively regulates GO:0043086 negative regulation of catalytic activity
Regulates GO:0050790 regulation of catalytic activity
Is a GO:0010280 UDP-L-rhamnose synthase activity
Is a GO:0000386 second spliceosomal transesterification activity
Is a GO:0000384 first spliceosomal transesterification activity
Is a GO:0070283 radical SAM enzyme activity
Is a GO:1990055 phenylacetaldehyde synthase activity
Is a GO:0030366 molybdopterin synthase activity
Is a GO:0044825 retroviral strand transfer activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0003824. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0003824 based on the entire annotation set Co-occurrence statistics for GO:0003824 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_plant
2013-04-18 Updated SLIM goslim_pir
2012-04-26 Deleted SLIM goslim_metagenomics
2012-02-17 Added SLIM goslim_metagenomics
2011-03-18 Deleted SLIM goslim_goa
2010-12-05 Deleted SLIM goslim_generic
2010-07-16 Added RELATION part of GO:0008152 (metabolic process)
2009-02-25 Added XREF Wikipedia:Enzyme
2009-01-15 Added SYNONYM enzyme activity
2009-01-15 Deleted SYNONYM enzyme activity
2008-06-09 Added SLIM goslim_plant
2008-06-09 Added SLIM goslim_pir
2008-06-09 Added SLIM goslim_goa
2008-06-09 Added SLIM goslim_generic
2008-05-13 Added DEFINITION Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
2008-05-12 Deleted DEFINITION Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
2008-04-01 Updated RELATION is a GO:0003674 (molecular_function)
2007-08-09 Added SYNONYM enzyme activity
2007-08-09 Deleted SYNONYM enzyme activity
2004-04-19 Added SYNONYM enzyme activity
2004-04-05 Deleted SYNONYM enzyme activity
2003-08-06 Updated DEFINITION Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
2003-07-01 Updated DEFINITION Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
2003-06-25 Updated DEFINITION Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
2003-06-24 Updated TERM catalytic activity
2003-06-24 Added SYNONYM enzyme activity
2003-05-03 Updated DEFINITION Catalysis of a biochemical reaction at relatively low temperatures. The substances upon which they act are known as substrates, for which the enzyme possesses a specific binding or active site. Enzymes are usually naturally occurring or synthetic macromolecular substance composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
2003-03-19 Updated TERM enzyme activity
2002-11-27 Updated DEFINITION Any naturally occurring or synthetic macromolecular substance composed wholly or largely of protein, that catalyzes, more or less specifically, one or more biochemical reactions at relatively low temperatures. The action of RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. Nevertheless, enzymes are mainly proteinaceous and are often easily inactivated by heating or by protein-denaturing agents. The substances upon which they act are known as substrates, for which the enzyme possesses a specific binding or active site.
2001-08-06 Added DEFINITION Any naturally occurring or synthetic macromoleular substance composed wholly or largely of protein, that catalyzes, more or less specifically, one or more (bio)chemical reactions at relatively low temperatures. The action of RNA that has catalytic activity (ribozyme) is often also regarded as enzymic. Nevertheless, enzymes are mainly proteinaceous and are often easily inactivated by heating or by protein-denaturing agents. The substances upon which they act are known as substrates, for which the enzyme possesses a specific binding or active site.
2001-04-03 Updated TERM enzyme
2001-03-30 Added TERM enzyme

Term

Timestamp Action Category Detail
2003-06-24 Updated TERM catalytic activity
2003-03-19 Updated TERM enzyme activity
2001-04-03 Updated TERM enzyme
2001-03-30 Added TERM enzyme

Definition/synonyms

Timestamp Action Category Detail
2009-01-15 Added SYNONYM enzyme activity
2009-01-15 Deleted SYNONYM enzyme activity
2008-05-13 Added DEFINITION Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
2008-05-12 Deleted DEFINITION Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
2007-08-09 Added SYNONYM enzyme activity
2007-08-09 Deleted SYNONYM enzyme activity
2004-04-19 Added SYNONYM enzyme activity
2004-04-05 Deleted SYNONYM enzyme activity
2003-08-06 Updated DEFINITION Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
2003-07-01 Updated DEFINITION Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
2003-06-25 Updated DEFINITION Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
2003-06-24 Added SYNONYM enzyme activity
2003-05-03 Updated DEFINITION Catalysis of a biochemical reaction at relatively low temperatures. The substances upon which they act are known as substrates, for which the enzyme possesses a specific binding or active site. Enzymes are usually naturally occurring or synthetic macromolecular substance composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
2002-11-27 Updated DEFINITION Any naturally occurring or synthetic macromolecular substance composed wholly or largely of protein, that catalyzes, more or less specifically, one or more biochemical reactions at relatively low temperatures. The action of RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. Nevertheless, enzymes are mainly proteinaceous and are often easily inactivated by heating or by protein-denaturing agents. The substances upon which they act are known as substrates, for which the enzyme possesses a specific binding or active site.
2001-08-06 Added DEFINITION Any naturally occurring or synthetic macromoleular substance composed wholly or largely of protein, that catalyzes, more or less specifically, one or more (bio)chemical reactions at relatively low temperatures. The action of RNA that has catalytic activity (ribozyme) is often also regarded as enzymic. Nevertheless, enzymes are mainly proteinaceous and are often easily inactivated by heating or by protein-denaturing agents. The substances upon which they act are known as substrates, for which the enzyme possesses a specific binding or active site.

Relationships

Timestamp Action Category Detail
2010-07-16 Added RELATION part of GO:0008152 (metabolic process)
2008-04-01 Updated RELATION is a GO:0003674 (molecular_function)

Cross-references

Timestamp Action Category Detail
2009-02-25 Added XREF Wikipedia:Enzyme

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_plant
2013-04-18 Updated SLIM goslim_pir
2012-04-26 Deleted SLIM goslim_metagenomics
2012-02-17 Added SLIM goslim_metagenomics
2011-03-18 Deleted SLIM goslim_goa
2010-12-05 Deleted SLIM goslim_generic
2008-06-09 Added SLIM goslim_plant
2008-06-09 Added SLIM goslim_pir
2008-06-09 Added SLIM goslim_goa
2008-06-09 Added SLIM goslim_generic
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
162ms