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GO:0003823 antigen binding

Term Information

ID GO:0003823
Name antigen binding
Ontology Molecular Function
Definition Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
GONUTS GO:0003823 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related immunoglobulin
related antibody
related B cell receptor activity
related opsonin activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Binding term considerationsLink

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_pir462

Cross-references

Database ID
UniProtKB-KW Immunoglobulin C region
UniProtKB-KW Immunoglobulin V region
UniProtKB-KW Monoclonal antibody

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0004892 B cell receptor activity CONSIDER GO:0003823
GO:0008229 opsonin activity CONSIDER GO:0003823
GO:0043498 cell surface binding CONSIDER GO:0003823
GO:0043499 eukaryotic cell surface binding CONSIDER GO:0003823
GO:0051635 bacterial cell surface binding CONSIDER GO:0003823
GO:0051636 Gram-negative bacterial cell surface binding CONSIDER GO:0003823
GO:0051637 Gram-positive bacterial cell surface binding CONSIDER GO:0003823

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0003823:
Relationship To GO:0003823 Child Term Child Term Name
Is a GO:0030882 lipid antigen binding
Is a GO:0042605 peptide antigen binding
Is a GO:0023023 MHC protein complex binding
Is a GO:1990405 protein antigen binding

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
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Date
Assigned By
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0003823. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0003823 based on the entire annotation set Co-occurrence statistics for GO:0003823 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_pir
2012-03-28 Added RELATION has part GO:0097282 (immunoglobulin-mediated neutralization)
2012-03-28 Added RELATION has part GO:0097281 (immune complex formation)
2012-03-28 Added RELATION has part GO:0097280 (histamine secretion mediated by immunoglobulin)
2012-03-28 Deleted RELATION has part GO:0097279 (histamine secretion mediated by IgE immunoglobulin)
2012-03-24 Added RELATION has part GO:0097279 (histamine secretion mediated by IgE immunoglobulin)
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
2009-07-03 Deleted DEFINITION Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
2008-06-09 Added SLIM goslim_pir
2008-05-13 Added DEFINITION Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
2008-05-12 Deleted DEFINITION Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
2008-04-01 Updated RELATION is a GO:0005488 (binding)
2007-08-09 Added SYNONYM B cell receptor activity
2007-08-09 Added SYNONYM antibody
2007-08-09 Added SYNONYM immunoglobulin
2007-08-09 Added SYNONYM opsonin activity
2007-08-09 Deleted SYNONYM B cell receptor activity
2007-08-09 Deleted SYNONYM antibody
2007-08-09 Deleted SYNONYM immunoglobulin
2007-08-09 Deleted SYNONYM opsonin activity
2005-08-10 Added SYNONYM B cell receptor activity
2005-08-10 Added SYNONYM opsonin activity
2003-06-10 Updated TERM antigen binding
2003-05-02 Updated DEFINITION Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
2003-04-24 Updated DEFINITION The function of binding noncovalently, reversibly, and in a specific manner with a corresponding antigen. Binding may counteract the biological activity of the antigen.
2003-03-26 Updated DEFINITION The function of binding non-covalently, reversibly, and in a specific manner with a corresponding antigen. Binding may counteract the biological activity of the antigen.
2003-03-19 Updated TERM antigen binding activity
2002-11-27 Added DEFINITION The function of binding non-covalently, reversibly, and in a specific manner with a corresponding antigen and frequently, but not always, counteracting the biological activity of that antigen.
2002-11-22 Updated TERM antigen binding
2002-11-22 Added SYNONYM antibody
2002-02-06 Updated TERM antibody
2001-11-27 Added SYNONYM immunoglobulin
2001-11-27 Updated TERM antibody
2001-04-03 Updated TERM immunoglobulin
2001-03-30 Added TERM immunoglobulin

Term

Timestamp Action Category Detail
2003-06-10 Updated TERM antigen binding
2003-03-19 Updated TERM antigen binding activity
2002-11-22 Updated TERM antigen binding
2002-02-06 Updated TERM antibody
2001-11-27 Updated TERM antibody
2001-04-03 Updated TERM immunoglobulin
2001-03-30 Added TERM immunoglobulin

Definition/synonyms

Timestamp Action Category Detail
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
2009-07-03 Deleted DEFINITION Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
2008-05-13 Added DEFINITION Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
2008-05-12 Deleted DEFINITION Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
2007-08-09 Added SYNONYM B cell receptor activity
2007-08-09 Added SYNONYM antibody
2007-08-09 Added SYNONYM immunoglobulin
2007-08-09 Added SYNONYM opsonin activity
2007-08-09 Deleted SYNONYM B cell receptor activity
2007-08-09 Deleted SYNONYM antibody
2007-08-09 Deleted SYNONYM immunoglobulin
2007-08-09 Deleted SYNONYM opsonin activity
2005-08-10 Added SYNONYM B cell receptor activity
2005-08-10 Added SYNONYM opsonin activity
2003-05-02 Updated DEFINITION Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
2003-04-24 Updated DEFINITION The function of binding noncovalently, reversibly, and in a specific manner with a corresponding antigen. Binding may counteract the biological activity of the antigen.
2003-03-26 Updated DEFINITION The function of binding non-covalently, reversibly, and in a specific manner with a corresponding antigen. Binding may counteract the biological activity of the antigen.
2002-11-27 Added DEFINITION The function of binding non-covalently, reversibly, and in a specific manner with a corresponding antigen and frequently, but not always, counteracting the biological activity of that antigen.
2002-11-22 Added SYNONYM antibody
2001-11-27 Added SYNONYM immunoglobulin

Relationships

Timestamp Action Category Detail
2012-03-28 Added RELATION has part GO:0097282 (immunoglobulin-mediated neutralization)
2012-03-28 Added RELATION has part GO:0097281 (immune complex formation)
2012-03-28 Added RELATION has part GO:0097280 (histamine secretion mediated by immunoglobulin)
2012-03-28 Deleted RELATION has part GO:0097279 (histamine secretion mediated by IgE immunoglobulin)
2012-03-24 Added RELATION has part GO:0097279 (histamine secretion mediated by IgE immunoglobulin)
2008-04-01 Updated RELATION is a GO:0005488 (binding)

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_pir
2008-06-09 Added SLIM goslim_pir
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