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GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity

Term Information

ID GO:0016538
Name cyclin-dependent protein serine/threonine kinase regulator activity
Ontology Molecular Function
Definition Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
PMID:7877684 PMID:9442875
Secondary IDs GO:0003751 GO:0003752 GO:0003753
GONUTS GO:0016538 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad cyclin-dependent protein kinase regulator activity
narrow G1/S-specific cyclin
narrow G2/M-specific cyclin
broad cyclin
narrow cyclin-dependent protein kinase, intrinsic regulator activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.7.1.-
InterPro IPR000789
InterPro IPR012388
InterPro IPR027081
InterPro IPR028367

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016538:
Relationship To GO:0016538 Child Term Child Term Name
Is a GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity
Is a GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016538. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016538 based on the entire annotation set Co-occurrence statistics for GO:0016538 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-03-08 Updated TERM cyclin-dependent protein serine/threonine kinase regulator activity
2013-03-08 Deleted DEFINITION Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
2013-03-08 Added DEFINITION Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
2013-03-08 Added SYNONYM cyclin-dependent protein kinase regulator activity
2010-06-15 Added RELATION regulates GO:0004693 (cyclin-dependent protein serine/threonine kinase activity)
2010-06-14 Deleted RELATION regulates GO:0004693 (cyclin-dependent protein serine/threonine kinase activity)
2010-06-08 Added RELATION regulates GO:0004693 (cyclin-dependent protein serine/threonine kinase activity)
2009-02-25 Deleted RELATION regulates GO:0004693 (cyclin-dependent protein serine/threonine kinase activity)
2009-02-22 Added RELATION regulates GO:0004693 (cyclin-dependent protein serine/threonine kinase activity)
2008-05-13 Added DEFINITION Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
2008-05-12 Deleted DEFINITION Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
2008-04-01 Updated RELATION is a GO:0019887 (protein kinase regulator activity)
2007-08-09 Added SYNONYM G1/S-specific cyclin
2007-08-09 Added SYNONYM G2/M-specific cyclin
2007-08-09 Added SYNONYM cyclin
2007-08-09 Added SYNONYM cyclin-dependent protein kinase, intrinsic regulator activity
2007-08-09 Deleted SYNONYM G1/S-specific cyclin
2007-08-09 Deleted SYNONYM G2/M-specific cyclin
2007-08-09 Deleted SYNONYM cyclin
2007-08-09 Deleted SYNONYM cyclin-dependent protein kinase, intrinsic regulator activity
2004-04-30 Updated DEFINITION Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
2004-04-19 Added SYNONYM G1/S-specific cyclin
2004-04-19 Added SYNONYM G2/M-specific cyclin
2004-04-19 Added SYNONYM cyclin
2004-04-19 Added SYNONYM cyclin-dependent protein kinase, intrinsic regulator activity
2004-04-17 Updated DEFINITION Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins.
2004-04-16 Deleted SYNONYM G2/M-specific cyclin
2004-04-16 Deleted SYNONYM cyclin
2004-04-16 Deleted SYNONYM cyclin-dependent protein kinase, intrinsic regulator activity
2004-04-16 Deleted SYNONYM G1/S-specific cyclin
2004-04-15 Added DEFINITION Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins
2003-12-20 Updated TERM cyclin-dependent protein kinase regulator activity
2003-12-20 Added SYNONYM cyclin-dependent protein kinase, intrinsic regulator activity
2003-07-08 Updated TERM cyclin-dependent protein kinase, intrinsic regulator activity
2003-03-19 Updated TERM cyclin-dependent protein kinase, regulator activity
2002-02-08 Added SYNONYM cyclin
2002-02-08 Added SYNONYM G2/M-specific cyclin
2002-02-08 Added SYNONYM G1/S-specific cyclin
2002-02-08 Added SECONDARY GO:0003753 (G2/M-specific cyclin)
2002-02-08 Added SECONDARY GO:0003752 (G1/S-specific cyclin)
2002-02-08 Added SECONDARY GO:0003751 (cyclin)
2002-02-06 Updated TERM cyclin-dependent protein kinase, regulator
2002-01-08 Updated TERM cyclin-dependent protein kinase, regulator
2001-04-03 Updated TERM cyclin-dependent protein kinase regulator
2001-03-30 Added XREF EC:2.7.1.-
2001-03-30 Added TERM cyclin-dependent protein kinase regulator

Term

Timestamp Action Category Detail
2013-03-08 Updated TERM cyclin-dependent protein serine/threonine kinase regulator activity
2003-12-20 Updated TERM cyclin-dependent protein kinase regulator activity
2003-07-08 Updated TERM cyclin-dependent protein kinase, intrinsic regulator activity
2003-03-19 Updated TERM cyclin-dependent protein kinase, regulator activity
2002-02-06 Updated TERM cyclin-dependent protein kinase, regulator
2002-01-08 Updated TERM cyclin-dependent protein kinase, regulator
2001-04-03 Updated TERM cyclin-dependent protein kinase regulator
2001-03-30 Added TERM cyclin-dependent protein kinase regulator

Definition/synonyms

Timestamp Action Category Detail
2013-03-08 Deleted DEFINITION Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
2013-03-08 Added DEFINITION Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
2013-03-08 Added SYNONYM cyclin-dependent protein kinase regulator activity
2008-05-13 Added DEFINITION Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
2008-05-12 Deleted DEFINITION Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
2007-08-09 Added SYNONYM G1/S-specific cyclin
2007-08-09 Added SYNONYM G2/M-specific cyclin
2007-08-09 Added SYNONYM cyclin
2007-08-09 Added SYNONYM cyclin-dependent protein kinase, intrinsic regulator activity
2007-08-09 Deleted SYNONYM G1/S-specific cyclin
2007-08-09 Deleted SYNONYM G2/M-specific cyclin
2007-08-09 Deleted SYNONYM cyclin
2007-08-09 Deleted SYNONYM cyclin-dependent protein kinase, intrinsic regulator activity
2004-04-30 Updated DEFINITION Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
2004-04-19 Added SYNONYM G1/S-specific cyclin
2004-04-19 Added SYNONYM G2/M-specific cyclin
2004-04-19 Added SYNONYM cyclin
2004-04-19 Added SYNONYM cyclin-dependent protein kinase, intrinsic regulator activity
2004-04-17 Updated DEFINITION Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins.
2004-04-16 Deleted SYNONYM G2/M-specific cyclin
2004-04-16 Deleted SYNONYM cyclin
2004-04-16 Deleted SYNONYM cyclin-dependent protein kinase, intrinsic regulator activity
2004-04-16 Deleted SYNONYM G1/S-specific cyclin
2004-04-15 Added DEFINITION Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins
2003-12-20 Added SYNONYM cyclin-dependent protein kinase, intrinsic regulator activity
2002-02-08 Added SYNONYM cyclin
2002-02-08 Added SYNONYM G2/M-specific cyclin
2002-02-08 Added SYNONYM G1/S-specific cyclin

Relationships

Timestamp Action Category Detail
2010-06-15 Added RELATION regulates GO:0004693 (cyclin-dependent protein serine/threonine kinase activity)
2010-06-14 Deleted RELATION regulates GO:0004693 (cyclin-dependent protein serine/threonine kinase activity)
2010-06-08 Added RELATION regulates GO:0004693 (cyclin-dependent protein serine/threonine kinase activity)
2009-02-25 Deleted RELATION regulates GO:0004693 (cyclin-dependent protein serine/threonine kinase activity)
2009-02-22 Added RELATION regulates GO:0004693 (cyclin-dependent protein serine/threonine kinase activity)
2008-04-01 Updated RELATION is a GO:0019887 (protein kinase regulator activity)

Cross-references

Timestamp Action Category Detail
2001-03-30 Added XREF EC:2.7.1.-

Other

Timestamp Action Category Detail
2002-02-08 Added SECONDARY GO:0003753 (G2/M-specific cyclin)
2002-02-08 Added SECONDARY GO:0003752 (G1/S-specific cyclin)
2002-02-08 Added SECONDARY GO:0003751 (cyclin)
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