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GO:0003743 translation initiation factor activity

Term Information

ID GO:0003743
Name translation initiation factor activity
Ontology Molecular Function
Definition Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
Secondary IDs GO:0003744 GO:0003745
GONUTS GO:0003743 Wiki Page

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Binding term considerationsLink

Cross-references

Database ID
InterPro IPR000178
InterPro IPR001040
InterPro IPR001253
InterPro IPR001288
InterPro IPR001950
InterPro IPR002735
InterPro IPR004368
InterPro IPR004458
InterPro IPR004544
InterPro IPR005872
InterPro IPR005874
InterPro IPR006196
InterPro IPR007316
InterPro IPR007783
InterPro IPR008732
InterPro IPR008905
InterPro IPR009374
InterPro IPR011400
InterPro IPR011488
InterPro IPR013906
InterPro IPR016020
InterPro IPR016189
InterPro IPR016190
InterPro IPR016650
InterPro IPR017334
InterPro IPR018104
InterPro IPR019382
InterPro IPR019770
InterPro IPR019813
InterPro IPR019814
InterPro IPR027516
InterPro IPR027524
InterPro IPR027525
InterPro IPR027528
InterPro IPR027531
UniProtKB-KW Initiation factor

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0016146 protein-synthesizing GTPase activity, initiation REPLACEDBY GO:0003743

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0003743:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0003743. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0003743 based on the entire annotation set Co-occurrence statistics for GO:0003743 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-12-01 Deleted RELATION part of GO:0045948 (positive regulation of translational initiation)
2010-06-15 Added RELATION part of GO:0045948 (positive regulation of translational initiation)
2010-06-15 Added RELATION part of GO:0006413 (translational initiation)
2010-06-14 Deleted RELATION part of GO:0045948 (positive regulation of translational initiation)
2010-06-14 Deleted RELATION part of GO:0006413 (translational initiation)
2010-06-09 Updated TERM translation initiation factor activity
2010-06-08 Added RELATION part of GO:0045948 (positive regulation of translational initiation)
2010-06-08 Added RELATION part of GO:0006413 (translational initiation)
2010-06-08 Updated TERM translation initiation factor activity
2008-05-13 Added DEFINITION Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
2008-05-12 Deleted DEFINITION Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
2008-04-01 Updated RELATION is a GO:0008135 (translation factor activity, nucleic acid binding)
2007-07-11 Deleted SYNONYM protein-synthesizing GTPase activity, initiation
2005-08-10 Added SYNONYM protein-synthesizing GTPase activity, initiation
2003-07-24 Updated DEFINITION Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
2003-03-19 Updated TERM translation initiation factor activity
2002-11-27 Updated DEFINITION Any of a group of soluble proteins functioning in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
2002-02-06 Updated TERM translation initiation factor
2001-08-06 Added DEFINITION any of a group of soluble proteins functioning in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
2001-04-03 Updated TERM translation initiation factor
2001-03-30 Added TERM translation initiation factor

Term

Timestamp Action Category Detail
2010-06-09 Updated TERM translation initiation factor activity
2010-06-08 Updated TERM translation initiation factor activity
2003-03-19 Updated TERM translation initiation factor activity
2002-02-06 Updated TERM translation initiation factor
2001-04-03 Updated TERM translation initiation factor
2001-03-30 Added TERM translation initiation factor

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
2008-05-12 Deleted DEFINITION Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
2007-07-11 Deleted SYNONYM protein-synthesizing GTPase activity, initiation
2005-08-10 Added SYNONYM protein-synthesizing GTPase activity, initiation
2003-07-24 Updated DEFINITION Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
2002-11-27 Updated DEFINITION Any of a group of soluble proteins functioning in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
2001-08-06 Added DEFINITION any of a group of soluble proteins functioning in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

Relationships

Timestamp Action Category Detail
2010-12-01 Deleted RELATION part of GO:0045948 (positive regulation of translational initiation)
2010-06-15 Added RELATION part of GO:0045948 (positive regulation of translational initiation)
2010-06-15 Added RELATION part of GO:0006413 (translational initiation)
2010-06-14 Deleted RELATION part of GO:0045948 (positive regulation of translational initiation)
2010-06-14 Deleted RELATION part of GO:0006413 (translational initiation)
2010-06-08 Added RELATION part of GO:0045948 (positive regulation of translational initiation)
2010-06-08 Added RELATION part of GO:0006413 (translational initiation)
2008-04-01 Updated RELATION is a GO:0008135 (translation factor activity, nucleic acid binding)
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