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GO:0003689 DNA clamp loader activity

Term Information

ID GO:0003689
Name DNA clamp loader activity
Ontology Molecular Function
Definition Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex.
PMID:16082778
GONUTS GO:0003689 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact DNA clamp loading ATPase activity
narrow PCNA loading activity
narrow PCNA loading complex activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Binding term considerationsLink
Considerations when annotating from ChiP assay resultsLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
InterPro IPR012178
InterPro IPR013725
InterPro IPR023748

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0003689:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0003689. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0003689 based on the entire annotation set Co-occurrence statistics for GO:0003689 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-09-03 Deleted DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex.
2010-09-03 Added DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex.
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex.
2008-04-01 Updated RELATION is a GO:0033170 (protein-DNA loading ATPase activity)
2008-04-01 Updated RELATION is a GO:0003677 (DNA binding)
2007-08-09 Added SYNONYM DNA clamp loading ATPase activity
2007-08-09 Added SYNONYM PCNA loading activity
2007-08-09 Added SYNONYM PCNA loading complex activity
2007-08-09 Deleted SYNONYM DNA clamp loading ATPase activity
2007-08-09 Deleted SYNONYM PCNA loading activity
2007-08-09 Deleted SYNONYM PCNA loading complex activity
2007-04-27 Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex.
2005-09-29 Updated DEFINITION Activity that loads a ring-like DNA polymerase processivity factor, or sliding clamp, on to DNA, coupled to the hydrolysis of ATP.
2005-09-29 Added SYNONYM DNA clamp loading ATPase activity
2005-09-29 Added SYNONYM PCNA loading activity
2005-09-29 Added SYNONYM PCNA loading complex activity
2003-03-19 Updated TERM DNA clamp loader activity
2002-11-27 Updated DEFINITION Protein complex that loads a ring-like DNA polymerase processivity factor (clamp) on to DNA.
2002-02-06 Updated TERM DNA clamp loader
2001-08-06 Added DEFINITION Protein complex that loads a ring-like DNA polymerase processivity factor (clamp) onto DNA.
2001-04-03 Updated TERM DNA clamp loader
2001-03-30 Added TERM DNA clamp loader

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM DNA clamp loader activity
2002-02-06 Updated TERM DNA clamp loader
2001-04-03 Updated TERM DNA clamp loader
2001-03-30 Added TERM DNA clamp loader

Definition/synonyms

Timestamp Action Category Detail
2010-09-03 Deleted DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex.
2010-09-03 Added DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex.
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex.
2007-08-09 Added SYNONYM DNA clamp loading ATPase activity
2007-08-09 Added SYNONYM PCNA loading activity
2007-08-09 Added SYNONYM PCNA loading complex activity
2007-08-09 Deleted SYNONYM DNA clamp loading ATPase activity
2007-08-09 Deleted SYNONYM PCNA loading activity
2007-08-09 Deleted SYNONYM PCNA loading complex activity
2007-04-27 Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex.
2005-09-29 Updated DEFINITION Activity that loads a ring-like DNA polymerase processivity factor, or sliding clamp, on to DNA, coupled to the hydrolysis of ATP.
2005-09-29 Added SYNONYM DNA clamp loading ATPase activity
2005-09-29 Added SYNONYM PCNA loading activity
2005-09-29 Added SYNONYM PCNA loading complex activity
2002-11-27 Updated DEFINITION Protein complex that loads a ring-like DNA polymerase processivity factor (clamp) on to DNA.
2001-08-06 Added DEFINITION Protein complex that loads a ring-like DNA polymerase processivity factor (clamp) onto DNA.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0033170 (protein-DNA loading ATPase activity)
2008-04-01 Updated RELATION is a GO:0003677 (DNA binding)
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