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GO:0003678 DNA helicase activity

Term Information

ID GO:0003678
Name DNA helicase activity
Ontology Molecular Function
Definition Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix.
Secondary IDs GO:0003679
GONUTS GO:0003678 Wiki Page

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
InterPro IPR000085
InterPro IPR006824
InterPro IPR007692
InterPro IPR007693
InterPro IPR007694
InterPro IPR008045
InterPro IPR008046
InterPro IPR008047
InterPro IPR008048
InterPro IPR008049
InterPro IPR008050
InterPro IPR009767
InterPro IPR010285
InterPro IPR010339

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0003678:
Relationship To GO:0003678 Child Term Child Term Name
Is a GO:0009378 four-way junction helicase activity
Is a GO:0004003 ATP-dependent DNA helicase activity
Is a GO:0043138 3'-5' DNA helicase activity
Is a GO:0043139 5'-3' DNA helicase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO ID
Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0003678. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0003678 based on the entire annotation set Co-occurrence statistics for GO:0003678 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-01-29 Added RELATION part of GO:0032508 (DNA duplex unwinding)
2010-09-03 Added DEFINITION Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix.
2010-09-03 Deleted DEFINITION Catalysis of the reaction: NTP + H2O = NDP + phosphate to drive the unwinding of a DNA helix.
2008-10-02 Added DEFINITION Catalysis of the reaction: NTP + H2O = NDP + phosphate to drive the unwinding of a DNA helix.
2008-10-02 Deleted DEFINITION Catalysis of the unwinding of a DNA duplex.
2008-05-13 Added DEFINITION Catalysis of the unwinding of a DNA duplex.
2008-05-12 Deleted DEFINITION Catalysis of the unwinding of a DNA duplex.
2008-04-01 Updated RELATION is a GO:0004386 (helicase activity)
2007-07-27 Updated DEFINITION Catalysis of the unwinding of a DNA duplex.
2007-05-27 Updated DEFINITION Catalysis of the hydrolysis of an NTP or dNTP to unwind the DNA helix.
2004-04-01 Updated DEFINITION Catalysis of the hydrolysis of ATP to unwind the DNA helix at the replication fork, allowing the resulting single strands to be copied.
2003-03-26 Added DEFINITION Catalysis of the the hydrolysis of ATP to unwind the DNA helix at the replication fork, allowing the resulting single strands to be copied.
2003-03-19 Updated TERM DNA helicase activity
2002-02-06 Updated TERM DNA helicase
2001-04-03 Updated TERM DNA helicase
2001-03-30 Added TERM DNA helicase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM DNA helicase activity
2002-02-06 Updated TERM DNA helicase
2001-04-03 Updated TERM DNA helicase
2001-03-30 Added TERM DNA helicase

Definition/synonyms

Timestamp Action Category Detail
2010-09-03 Added DEFINITION Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix.
2010-09-03 Deleted DEFINITION Catalysis of the reaction: NTP + H2O = NDP + phosphate to drive the unwinding of a DNA helix.
2008-10-02 Added DEFINITION Catalysis of the reaction: NTP + H2O = NDP + phosphate to drive the unwinding of a DNA helix.
2008-10-02 Deleted DEFINITION Catalysis of the unwinding of a DNA duplex.
2008-05-13 Added DEFINITION Catalysis of the unwinding of a DNA duplex.
2008-05-12 Deleted DEFINITION Catalysis of the unwinding of a DNA duplex.
2007-07-27 Updated DEFINITION Catalysis of the unwinding of a DNA duplex.
2007-05-27 Updated DEFINITION Catalysis of the hydrolysis of an NTP or dNTP to unwind the DNA helix.
2004-04-01 Updated DEFINITION Catalysis of the hydrolysis of ATP to unwind the DNA helix at the replication fork, allowing the resulting single strands to be copied.
2003-03-26 Added DEFINITION Catalysis of the the hydrolysis of ATP to unwind the DNA helix at the replication fork, allowing the resulting single strands to be copied.

Relationships

Timestamp Action Category Detail
2012-01-29 Added RELATION part of GO:0032508 (DNA duplex unwinding)
2008-04-01 Updated RELATION is a GO:0004386 (helicase activity)
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