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GO:0002755 MyD88-dependent toll-like receptor signaling pathway

Any series of molecular signals generated as a consequence of binding to a toll-like receptor and relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.

Term Information

ID GO:0002755
Name MyD88-dependent toll-like receptor signaling pathway
Ontology Biological Process
Definition Any series of molecular signals generated as a consequence of binding to a toll-like receptor and relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
Comment

Synonyms

Type Synonym
exact MyD88-dependent TLR signaling pathway
exact MyD88-dependent toll-like receptor signalling pathway

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Ancestor Chart

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Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0002376 immune system process
GO:0050896 response to stimulus
GO:0009987 cellular process
GO:0007154 cell communication
GO:0050789 regulation of biological process
GO:0006950 response to stress
GO:0048518 positive regulation of biological process
GO:0006952 defense response
GO:0006955 immune response
GO:0050794 regulation of cellular process
GO:0048583 regulation of response to stimulus
GO:0002682 regulation of immune system process
GO:0048584 positive regulation of response to stimulus
GO:0002684 positive regulation of immune system process
GO:0080134 regulation of response to stress
GO:0045087 innate immune response
GO:0007165 signal transduction
GO:0050776 regulation of immune response
GO:0031347 regulation of defense response
GO:0031349 positive regulation of defense response
GO:0050778 positive regulation of immune response
GO:0002253 activation of immune response
GO:0002764 immune response-regulating signal transduction
GO:0045088 regulation of innate immune response
GO:0002757 immune response-activating signal transduction
GO:0045089 positive regulation of innate immune response
GO:0002218 activation of innate immune response
GO:0002758 innate immune response-activating signal transduction
GO:0002221 pattern recognition receptor signaling pathway
GO:0002224 toll-like receptor signaling pathway
GO:0002755 MyD88-dependent toll-like receptor signaling pathway

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
R GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway
NR GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway
PR GO:0034126 positive regulation of MyD88-dependent toll-like receptor signaling pathway

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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