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GO:0002467 germinal center formation

The process by which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.

Term Information

ID GO:0002467
Name germinal center formation
Ontology Biological Process
Definition The process by which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.
Comment This term was added by GO_REF:0000022.

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Ancestor Chart

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Ancestor Table

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GO:0008150 biological_process
GO:0002376 immune system process
GO:0050896 response to stimulus
GO:0006955 immune response
GO:0002250 adaptive immune response
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
GO:0002467 germinal center formation

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
R GO:0002634 regulation of germinal center formation
NR GO:0002635 negative regulation of germinal center formation
PR GO:0002636 positive regulation of germinal center formation

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
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Taxonomy
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Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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