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GO:0002459 adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains

Term Information

ID GO:0002459
Name adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains
Ontology Biological Process
Definition An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae).
PMID:16373579
GONUTS GO:0002459 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact adaptive immune response in jawless fish
exact adaptive immune response based on somatic recombination of VLR built from LRR domains
exact adaptive immune response based on somatic recombination of variable lymphocyte receptors built from leucine-rich repeat domains

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0002376 immune system process never_in_taxon 4895 Schizosaccharomyces
GO:0002459 adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains only_in_taxon 89593 Craniata
More information on taxon constraints in GO is available here

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0002459:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0002459. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0002459 based on the entire annotation set Co-occurrence statistics for GO:0002459 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2016-11-13 Deleted DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae).
2016-11-13 Added DEFINITION An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae).
2009-07-11 Deleted SYNONYM adaptive immune response (sensu Myxinidae and Petromyzontidae)
2009-07-11 Added DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae).
2009-07-11 Deleted DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory).
2008-05-13 Added DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory).
2008-05-12 Deleted DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory).
2008-04-01 Updated RELATION is a GO:0002250 (adaptive immune response)
2007-08-09 Added SYNONYM adaptive immune response (sensu Myxinidae and Petromyzontidae)
2007-08-09 Added SYNONYM adaptive immune response based on somatic recombination of VLR built from LRR domains
2007-08-09 Added SYNONYM adaptive immune response based on somatic recombination of variable lymphocyte receptors built from leucine-rich repeat domains
2007-08-09 Added SYNONYM adaptive immune response in jawless fish
2007-08-09 Deleted SYNONYM adaptive immune response (sensu Myxinidae and Petromyzontidae)
2007-08-09 Deleted SYNONYM adaptive immune response based on somatic recombination of VLR built from LRR domains
2007-08-09 Deleted SYNONYM adaptive immune response based on somatic recombination of variable lymphocyte receptors built from leucine-rich repeat domains
2007-08-09 Deleted SYNONYM adaptive immune response in jawless fish
2007-04-20 Updated DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory).
2007-04-06 Added SYNONYM adaptive immune response (sensu Myxinidae and Petromyzontidae)
2007-04-06 Added SYNONYM adaptive immune response based on somatic recombination of VLR built from LRR domains
2007-04-06 Added SYNONYM adaptive immune response based on somatic recombination of variable lymphocyte receptors built from leucine-rich repeat domains
2007-04-06 Updated TERM adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains
2007-01-18 Updated TERM adaptive immune response (sensu Myxinidae and Petromyzontidae)
2007-01-15 Updated TERM adaptive immune response (sensu the Myxinidae and Petromyzontidae research community)
2006-09-22 Added DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory), as in, but not restricted to, hagfish and lamprays (Myxinidae, ncbi_taxonomy_id:7762, Petromyzontidae, ncbi_taxonomy_id:7746).
2006-09-21 Added SYNONYM adaptive immune response in jawless fish
2006-09-21 Added TERM adaptive immune response (sensu Myxinidae and Petromyzontidae)

Term

Timestamp Action Category Detail
2007-04-06 Updated TERM adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains
2007-01-18 Updated TERM adaptive immune response (sensu Myxinidae and Petromyzontidae)
2007-01-15 Updated TERM adaptive immune response (sensu the Myxinidae and Petromyzontidae research community)
2006-09-21 Added TERM adaptive immune response (sensu Myxinidae and Petromyzontidae)

Definition/synonyms

Timestamp Action Category Detail
2016-11-13 Deleted DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae).
2016-11-13 Added DEFINITION An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae).
2009-07-11 Deleted SYNONYM adaptive immune response (sensu Myxinidae and Petromyzontidae)
2009-07-11 Added DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae).
2009-07-11 Deleted DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory).
2008-05-13 Added DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory).
2008-05-12 Deleted DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory).
2007-08-09 Added SYNONYM adaptive immune response (sensu Myxinidae and Petromyzontidae)
2007-08-09 Added SYNONYM adaptive immune response based on somatic recombination of VLR built from LRR domains
2007-08-09 Added SYNONYM adaptive immune response based on somatic recombination of variable lymphocyte receptors built from leucine-rich repeat domains
2007-08-09 Added SYNONYM adaptive immune response in jawless fish
2007-08-09 Deleted SYNONYM adaptive immune response (sensu Myxinidae and Petromyzontidae)
2007-08-09 Deleted SYNONYM adaptive immune response based on somatic recombination of VLR built from LRR domains
2007-08-09 Deleted SYNONYM adaptive immune response based on somatic recombination of variable lymphocyte receptors built from leucine-rich repeat domains
2007-08-09 Deleted SYNONYM adaptive immune response in jawless fish
2007-04-20 Updated DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory).
2007-04-06 Added SYNONYM adaptive immune response (sensu Myxinidae and Petromyzontidae)
2007-04-06 Added SYNONYM adaptive immune response based on somatic recombination of VLR built from LRR domains
2007-04-06 Added SYNONYM adaptive immune response based on somatic recombination of variable lymphocyte receptors built from leucine-rich repeat domains
2006-09-22 Added DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory), as in, but not restricted to, hagfish and lamprays (Myxinidae, ncbi_taxonomy_id:7762, Petromyzontidae, ncbi_taxonomy_id:7746).
2006-09-21 Added SYNONYM adaptive immune response in jawless fish

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0002250 (adaptive immune response)
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