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GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response.

Term Information

ID GO:0002291
Name T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
Ontology Biological Process
Definition The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response.
Comment

Synonyms

Type Synonym
exact T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
exact T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
exact T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

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Ancestor Chart

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Ancestor Table

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0050896 response to stimulus
GO:0002376 immune system process
GO:0001775 cell activation
GO:0006955 immune response
GO:0045321 leukocyte activation
GO:0046649 lymphocyte activation
GO:0002263 cell activation during immune response
GO:0042110 T cell activation
GO:0002366 leukocyte activation during immune response
GO:0002285 lymphocyte activation during immune response
GO:0002286 T cell activation during immune response
GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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