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GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Term Information

ID GO:0001844
Name protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
Ontology Biological Process
Definition The process in which a protein is incorporated into a mitochondrial membrane as the initial phase of the mitochondrial membrane permeabilization that takes place in the apoptotic signaling pathway.
PMID:12952892
Comment Note that this term is intended to cover the insertion of pro-apoptotic proteins such as Bax or its homologs into mitochondrial membranes which occurs as an early step in the apoptotic program.
GONUTS GO:0001844 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow protein insertion into mitochondrial membrane during induction of apoptosis
narrow protein insertion into mitochondrion membrane during induction of apoptosis
narrow protein insertion into mitochondrial membrane involved in induction of apoptosis
narrow insertion of proteins into mitochondrial membranes during the induction of apoptosis

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating cell death and apoptosis using the new guidelinesLink

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0006915 apoptotic process only_in_taxon 33154 Opisthokonta
More information on taxon constraints in GO is available here

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0001844:
Relationship To GO:0001844 Child Term Child Term Name
Regulates GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
Positively regulates GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0001844. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0001844 based on the entire annotation set Co-occurrence statistics for GO:0001844 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-06-21 Added RELATION part of GO:0097345 (mitochondrial outer membrane permeabilization)
2012-06-21 Deleted RELATION is a GO:0008637 (apoptotic mitochondrial changes)
2012-05-27 Deleted RELATION part of GO:0006917 (induction of apoptosis)
2012-05-27 Deleted SYNONYM protein insertion into mitochondrion membrane during induction of apoptosis
2012-05-27 Deleted SYNONYM protein insertion into mitochondrial membrane during induction of apoptosis
2012-05-27 Added SYNONYM protein insertion into mitochondrial membrane involved in induction of apoptosis
2012-05-27 Added SYNONYM protein insertion into mitochondrion membrane during induction of apoptosis
2012-05-27 Added RELATION part of GO:0097190 (apoptotic signaling pathway)
2012-05-27 Added SYNONYM protein insertion into mitochondrial membrane during induction of apoptosis
2012-05-27 Added SYNONYM insertion of proteins into mitochondrial membranes during the induction of apoptosis
2012-05-27 Added DEFINITION The process in which a protein is incorporated into a mitochondrial membrane as the initial phase of the mitochondrial membrane permeabilization that takes place in the apoptotic signaling pathway.
2012-05-27 Deleted SYNONYM insertion of proteins into mitochondrial membranes during the induction of apoptosis
2012-05-27 Updated TERM protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
2012-05-27 Deleted DEFINITION The process in which a protein is incorporated into a mitochondrial membrane, contributing to the induction of apoptosis.
2010-11-17 Added DEFINITION The process in which a protein is incorporated into a mitochondrial membrane, contributing to the induction of apoptosis.
2010-11-17 Deleted DEFINITION The process by which a protein is incorporated into a mitochondrial membrane that contributes to the induction of apoptosis.
2010-06-14 Updated TERM protein insertion into mitochondrial membrane involved in induction of apoptosis
2010-06-14 Added DEFINITION The process by which a protein is incorporated into a mitochondrial membrane that contributes to the induction of apoptosis.
2010-06-14 Deleted DEFINITION The process by which a protein is incorporated into a mitochondrial membrane as an early step in apoptosis.
2010-06-14 Added SYNONYM protein insertion into mitochondrial membrane during induction of apoptosis
2008-05-13 Added DEFINITION The process by which a protein is incorporated into a mitochondrial membrane as an early step in apoptosis.
2008-05-12 Deleted DEFINITION The process by which a protein is incorporated into a mitochondrial membrane as an early step in apoptosis.
2008-04-01 Updated RELATION part of GO:0006917 (induction of apoptosis)
2008-04-01 Updated RELATION is a GO:0008637 (apoptotic mitochondrial changes)
2008-04-01 Updated RELATION is a GO:0051204 (protein insertion into mitochondrial membrane)
2007-08-09 Added SYNONYM insertion of proteins into mitochondrial membranes during the induction of apoptosis
2007-08-09 Added SYNONYM protein insertion into mitochondrion membrane during induction of apoptosis
2007-08-09 Deleted SYNONYM insertion of proteins into mitochondrial membranes during the induction of apoptosis
2007-08-09 Deleted SYNONYM protein insertion into mitochondrion membrane during induction of apoptosis
2004-11-05 Added SYNONYM insertion of proteins into mitochondrial membranes during the induction of apoptosis
2004-11-05 Added SYNONYM protein insertion into mitochondrion membrane during induction of apoptosis
2004-11-05 Updated TERM protein insertion into mitochondrial membrane during induction of apoptosis
2004-11-05 Updated DEFINITION The process by which a protein is incorporated into a mitochondrial membrane as an early step in apoptosis.
2004-03-20 Added DEFINITION The insertion of particular proteins into mitochondrial membranes as an early step in apoptosis.
2004-03-20 Added TERM insertion of proteins into mitochondrial membranes during the induction of apoptosis

Term

Timestamp Action Category Detail
2012-05-27 Updated TERM protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
2010-06-14 Updated TERM protein insertion into mitochondrial membrane involved in induction of apoptosis
2004-11-05 Updated TERM protein insertion into mitochondrial membrane during induction of apoptosis
2004-03-20 Added TERM insertion of proteins into mitochondrial membranes during the induction of apoptosis

Definition/synonyms

Timestamp Action Category Detail
2012-05-27 Deleted SYNONYM protein insertion into mitochondrion membrane during induction of apoptosis
2012-05-27 Deleted SYNONYM protein insertion into mitochondrial membrane during induction of apoptosis
2012-05-27 Added SYNONYM protein insertion into mitochondrial membrane involved in induction of apoptosis
2012-05-27 Added SYNONYM protein insertion into mitochondrion membrane during induction of apoptosis
2012-05-27 Added SYNONYM protein insertion into mitochondrial membrane during induction of apoptosis
2012-05-27 Added SYNONYM insertion of proteins into mitochondrial membranes during the induction of apoptosis
2012-05-27 Added DEFINITION The process in which a protein is incorporated into a mitochondrial membrane as the initial phase of the mitochondrial membrane permeabilization that takes place in the apoptotic signaling pathway.
2012-05-27 Deleted SYNONYM insertion of proteins into mitochondrial membranes during the induction of apoptosis
2012-05-27 Deleted DEFINITION The process in which a protein is incorporated into a mitochondrial membrane, contributing to the induction of apoptosis.
2010-11-17 Added DEFINITION The process in which a protein is incorporated into a mitochondrial membrane, contributing to the induction of apoptosis.
2010-11-17 Deleted DEFINITION The process by which a protein is incorporated into a mitochondrial membrane that contributes to the induction of apoptosis.
2010-06-14 Added DEFINITION The process by which a protein is incorporated into a mitochondrial membrane that contributes to the induction of apoptosis.
2010-06-14 Deleted DEFINITION The process by which a protein is incorporated into a mitochondrial membrane as an early step in apoptosis.
2010-06-14 Added SYNONYM protein insertion into mitochondrial membrane during induction of apoptosis
2008-05-13 Added DEFINITION The process by which a protein is incorporated into a mitochondrial membrane as an early step in apoptosis.
2008-05-12 Deleted DEFINITION The process by which a protein is incorporated into a mitochondrial membrane as an early step in apoptosis.
2007-08-09 Added SYNONYM insertion of proteins into mitochondrial membranes during the induction of apoptosis
2007-08-09 Added SYNONYM protein insertion into mitochondrion membrane during induction of apoptosis
2007-08-09 Deleted SYNONYM insertion of proteins into mitochondrial membranes during the induction of apoptosis
2007-08-09 Deleted SYNONYM protein insertion into mitochondrion membrane during induction of apoptosis
2004-11-05 Added SYNONYM insertion of proteins into mitochondrial membranes during the induction of apoptosis
2004-11-05 Added SYNONYM protein insertion into mitochondrion membrane during induction of apoptosis
2004-11-05 Updated DEFINITION The process by which a protein is incorporated into a mitochondrial membrane as an early step in apoptosis.
2004-03-20 Added DEFINITION The insertion of particular proteins into mitochondrial membranes as an early step in apoptosis.

Relationships

Timestamp Action Category Detail
2012-06-21 Added RELATION part of GO:0097345 (mitochondrial outer membrane permeabilization)
2012-06-21 Deleted RELATION is a GO:0008637 (apoptotic mitochondrial changes)
2012-05-27 Deleted RELATION part of GO:0006917 (induction of apoptosis)
2012-05-27 Added RELATION part of GO:0097190 (apoptotic signaling pathway)
2008-04-01 Updated RELATION part of GO:0006917 (induction of apoptosis)
2008-04-01 Updated RELATION is a GO:0008637 (apoptotic mitochondrial changes)
2008-04-01 Updated RELATION is a GO:0051204 (protein insertion into mitochondrial membrane)
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