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GO:0001816 cytokine production

Term Information

ID GO:0001816
Name cytokine production
Ontology Biological Process
Definition The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Comment Note that this term is intended for use when a gene product is seen to cause apparent increases in intracellular or extracellular cytokine levels, without specific regard as to whether the increase is due to increased biosynthesis, increased secretion of preexisting cytokine molecules, or increased conversion from precursor molecules.
GONUTS GO:0001816 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow interferon production
narrow interleukin production

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to terms describing protein or chemical productionLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000299 GO:0032501 multicellular organismal process only_in_taxon 2759 Eukaryota
GOTAX:0000537 GO:0032501 multicellular organismal process never_in_taxon 4932 Saccharomyces cerevisiae
GOTAX:0000538 GO:0032501 multicellular organismal process never_in_taxon 4896 Schizosaccharomyces pombe
More information on taxon constraints in GO is available here

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_pir462

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0001816:
Relationship To GO:0001816 Child Term Child Term Name
Part of GO:0042089 cytokine biosynthetic process
Part of GO:0050663 cytokine secretion
Regulates GO:0001817 regulation of cytokine production
Negatively regulates GO:0001818 negative regulation of cytokine production
Positively regulates GO:0001819 positive regulation of cytokine production
Is a GO:0002534 cytokine production involved in inflammatory response
Is a GO:0010573 vascular endothelial growth factor production
Is a GO:0044807 macrophage migration inhibitory factor production
Is a GO:0044808 Oncostatin M production
Is a GO:0002367 cytokine production involved in immune response
Is a GO:0002390 platelet activating factor production
Is a GO:0090360 platelet-derived growth factor production
Is a GO:0032601 connective tissue growth factor production
Is a GO:0032602 chemokine production
Is a GO:0032604 granulocyte macrophage colony-stimulating factor production
Is a GO:0032605 hepatocyte growth factor production
Is a GO:0032606 type I interferon production
Is a GO:0032609 interferon-gamma production
Is a GO:0032612 interleukin-1 production
Is a GO:0032613 interleukin-10 production
Is a GO:0032614 interleukin-11 production
Is a GO:0032615 interleukin-12 production
Is a GO:0032616 interleukin-13 production
Is a GO:0032617 interleukin-14 production
Is a GO:0032618 interleukin-15 production
Is a GO:0032619 interleukin-16 production
Is a GO:0032620 interleukin-17 production
Is a GO:0032621 interleukin-18 production
Is a GO:0032622 interleukin-19 production
Is a GO:0032623 interleukin-2 production
Is a GO:0032624 interleukin-20 production
Is a GO:0032625 interleukin-21 production
Is a GO:0032626 interleukin-22 production
Is a GO:0032627 interleukin-23 production
Is a GO:0032628 interleukin-24 production
Is a GO:0032629 interleukin-25 production
Is a GO:0032630 interleukin-26 production
Is a GO:0032631 interleukin-27 production
Is a GO:0032632 interleukin-3 production
Is a GO:0032633 interleukin-4 production
Is a GO:0032634 interleukin-5 production
Is a GO:0032635 interleukin-6 production
Is a GO:0032636 interleukin-7 production
Is a GO:0032637 interleukin-8 production
Is a GO:0032638 interleukin-9 production
Is a GO:0071604 transforming growth factor beta production
Is a GO:0071611 granulocyte colony-stimulating factor production
Is a GO:0090269 fibroblast growth factor production
Is a GO:0090270 regulation of fibroblast growth factor production
Is a GO:0034343 type III interferon production
Is a GO:0071706 tumor necrosis factor superfamily cytokine production
Is a GO:0072633 interleukin-30 production
Is a GO:0072635 interleukin-31 production
Is a GO:0072637 interleukin-32 production
Is a GO:0072639 interleukin-33 production
Is a GO:0070753 interleukin-35 production
Is a GO:0036301 macrophage colony-stimulating factor production

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO ID
Original GO Term Name
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Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0001816. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0001816 based on the entire annotation set Co-occurrence statistics for GO:0001816 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_pir
2012-09-29 Added RELATION is a GO:0044707 (single-multicellular organism process)
2012-09-29 Deleted RELATION is a GO:0032501 (multicellular organismal process)
2011-01-19 Added SYNONYM interferon production
2011-01-19 Added SYNONYM interleukin production
2008-06-09 Added SLIM goslim_pir
2008-05-13 Added DEFINITION The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
2008-05-12 Deleted DEFINITION The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
2008-04-01 Updated RELATION is a GO:0032501 (multicellular organismal process)
2006-09-19 Updated DEFINITION The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
2004-02-05 Added DEFINITION The synthesis and release of a cytokine following a stimulus, resulting in an increase in its intracellular or extracellular levels.
2004-02-05 Added TERM cytokine production

Term

Timestamp Action Category Detail
2004-02-05 Added TERM cytokine production

Definition/synonyms

Timestamp Action Category Detail
2011-01-19 Added SYNONYM interferon production
2011-01-19 Added SYNONYM interleukin production
2008-05-13 Added DEFINITION The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
2008-05-12 Deleted DEFINITION The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
2006-09-19 Updated DEFINITION The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
2004-02-05 Added DEFINITION The synthesis and release of a cytokine following a stimulus, resulting in an increase in its intracellular or extracellular levels.

Relationships

Timestamp Action Category Detail
2012-09-29 Added RELATION is a GO:0044707 (single-multicellular organism process)
2012-09-29 Deleted RELATION is a GO:0032501 (multicellular organismal process)
2008-04-01 Updated RELATION is a GO:0032501 (multicellular organismal process)

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_pir
2008-06-09 Added SLIM goslim_pir
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