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GO:0001788 antibody-dependent cellular cytotoxicity

Term Information

ID GO:0001788
Name antibody-dependent cellular cytotoxicity
Ontology Biological Process
Definition Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.
PMID:11677095 PMID:9581795
GONUTS GO:0001788 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact antibody dependent cell death
exact ADCC
exact antibody-dependent cell death
exact antibody dependent cell killing
exact antibody-dependent cell killing
exact type VI hypersensitivity

Cross-references

Database ID
Wikipedia Antibody-dependent_cell-mediated_cytotoxicity
Wikipedia Antibody-dependent_cellular_cytotoxicity

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0001788:
Relationship To GO:0001788 Child Term Child Term Name
Regulates GO:0001813 regulation of antibody-dependent cellular cytotoxicity
Negatively regulates GO:0001814 negative regulation of antibody-dependent cellular cytotoxicity
Positively regulates GO:0001815 positive regulation of antibody-dependent cellular cytotoxicity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO ID
Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0001788. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0001788 based on the entire annotation set Co-occurrence statistics for GO:0001788 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-12-23 Added RELATION is a GO:0044699 (single-organism process)
2012-09-28 Deleted RELATION is a GO:0006917 (induction of apoptosis)
2009-02-25 Added XREF Wikipedia:Antibody-dependent_cellular_cytotoxicity
2009-02-25 Added XREF Wikipedia:Antibody-dependent_cell-mediated_cytotoxicity
2008-05-13 Added DEFINITION Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.
2008-05-12 Deleted DEFINITION Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.
2008-04-01 Updated RELATION is a GO:0006917 (induction of apoptosis)
2008-04-01 Updated RELATION is a GO:0001794 (type IIa hypersensitivity)
2008-04-01 Updated RELATION is a GO:0001909 (leukocyte mediated cytotoxicity)
2007-08-09 Added SYNONYM ADCC
2007-08-09 Added SYNONYM antibody dependent cell death
2007-08-09 Added SYNONYM antibody dependent cell killing
2007-08-09 Added SYNONYM antibody-dependent cell death
2007-08-09 Added SYNONYM antibody-dependent cell killing
2007-08-09 Added SYNONYM type VI hypersensitivity
2007-08-09 Deleted SYNONYM ADCC
2007-08-09 Deleted SYNONYM antibody dependent cell death
2007-08-09 Deleted SYNONYM antibody dependent cell killing
2007-08-09 Deleted SYNONYM antibody-dependent cell death
2007-08-09 Deleted SYNONYM antibody-dependent cell killing
2007-08-09 Deleted SYNONYM type VI hypersensitivity
2005-10-22 Added SYNONYM antibody dependent cell death
2005-10-22 Added SYNONYM antibody dependent cell killing
2005-10-22 Added SYNONYM antibody-dependent cell death
2005-10-22 Added SYNONYM antibody-dependent cell killing
2004-04-19 Added SYNONYM ADCC
2004-04-19 Added SYNONYM type VI hypersensitivity
2004-04-16 Deleted SYNONYM type VI hypersensitivity
2004-04-16 Deleted SYNONYM ADCC
2004-03-05 Updated DEFINITION Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.
2004-02-05 Added SYNONYM type VI hypersensitivity
2004-01-13 Added SYNONYM ADCC
2004-01-13 Added TERM antibody-dependent cellular cytotoxicity
2004-01-13 Added DEFINITION Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or machrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.

Term

Timestamp Action Category Detail
2004-01-13 Added TERM antibody-dependent cellular cytotoxicity

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.
2008-05-12 Deleted DEFINITION Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.
2007-08-09 Added SYNONYM ADCC
2007-08-09 Added SYNONYM antibody dependent cell death
2007-08-09 Added SYNONYM antibody dependent cell killing
2007-08-09 Added SYNONYM antibody-dependent cell death
2007-08-09 Added SYNONYM antibody-dependent cell killing
2007-08-09 Added SYNONYM type VI hypersensitivity
2007-08-09 Deleted SYNONYM ADCC
2007-08-09 Deleted SYNONYM antibody dependent cell death
2007-08-09 Deleted SYNONYM antibody dependent cell killing
2007-08-09 Deleted SYNONYM antibody-dependent cell death
2007-08-09 Deleted SYNONYM antibody-dependent cell killing
2007-08-09 Deleted SYNONYM type VI hypersensitivity
2005-10-22 Added SYNONYM antibody dependent cell death
2005-10-22 Added SYNONYM antibody dependent cell killing
2005-10-22 Added SYNONYM antibody-dependent cell death
2005-10-22 Added SYNONYM antibody-dependent cell killing
2004-04-19 Added SYNONYM ADCC
2004-04-19 Added SYNONYM type VI hypersensitivity
2004-04-16 Deleted SYNONYM type VI hypersensitivity
2004-04-16 Deleted SYNONYM ADCC
2004-03-05 Updated DEFINITION Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.
2004-02-05 Added SYNONYM type VI hypersensitivity
2004-01-13 Added SYNONYM ADCC
2004-01-13 Added DEFINITION Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or machrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.

Relationships

Timestamp Action Category Detail
2012-12-23 Added RELATION is a GO:0044699 (single-organism process)
2012-09-28 Deleted RELATION is a GO:0006917 (induction of apoptosis)
2008-04-01 Updated RELATION is a GO:0006917 (induction of apoptosis)
2008-04-01 Updated RELATION is a GO:0001794 (type IIa hypersensitivity)
2008-04-01 Updated RELATION is a GO:0001909 (leukocyte mediated cytotoxicity)

Cross-references

Timestamp Action Category Detail
2009-02-25 Added XREF Wikipedia:Antibody-dependent_cellular_cytotoxicity
2009-02-25 Added XREF Wikipedia:Antibody-dependent_cell-mediated_cytotoxicity
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