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GO:0001788 antibody-dependent cellular cytotoxicity

Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.

Term Information

ID GO:0001788
Name antibody-dependent cellular cytotoxicity
Ontology Biological Process
Definition Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.
Comment

Synonyms

Type Synonym
exact antibody-dependent cell death
exact antibody-dependent cell killing
exact antibody dependent cell death
exact ADCC
exact antibody dependent cell killing
exact type VI hypersensitivity

Cross-references associated with this term:

Database ID
Wikipedia Antibody-dependent_cellular_cytotoxicity
Wikipedia Antibody-dependent_cell-mediated_cytotoxicity

Web service: term information

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GTerm?id=termID&format=format

Full details can be found on the QuickGO Web Services page.

Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0008150 biological_process
GO:0009987 cellular process
GO:0065007 biological regulation
GO:0001906 cell killing
GO:0002376 immune system process
GO:0050896 response to stimulus
GO:0016265 death
GO:0006950 response to stress
GO:0050789 regulation of biological process
GO:0009605 response to external stimulus
GO:0006955 immune response
GO:0008219 cell death
GO:0048518 positive regulation of biological process
GO:0006952 defense response
GO:0050794 regulation of cellular process
GO:0009611 response to wounding
GO:0002252 immune effector process
GO:0012501 programmed cell death
GO:0002250 adaptive immune response
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
GO:0002443 leukocyte mediated immunity
GO:0006915 apoptosis
GO:0006954 inflammatory response
GO:0048522 positive regulation of cellular process
GO:0002449 lymphocyte mediated immunity
GO:0002444 myeloid leukocyte mediated immunity
GO:0001909 leukocyte mediated cytotoxicity
GO:0002526 acute inflammatory response
GO:0010941 regulation of cell death
GO:0043067 regulation of programmed cell death
GO:0002437 inflammatory response to antigenic stimulus
GO:0019724 B cell mediated immunity
GO:0016064 immunoglobulin mediated immune response
GO:0010942 positive regulation of cell death
GO:0042981 regulation of apoptosis
GO:0002438 acute inflammatory response to antigenic stimulus
GO:0002524 hypersensitivity
GO:0043068 positive regulation of programmed cell death
GO:0012502 induction of programmed cell death
GO:0043065 positive regulation of apoptosis
GO:0006917 induction of apoptosis
GO:0002445 type II hypersensitivity
GO:0001794 type IIa hypersensitivity
GO:0001788 antibody-dependent cellular cytotoxicity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
R GO:0001813 regulation of antibody-dependent cellular cytotoxicity
NR GO:0001814 negative regulation of antibody-dependent cellular cytotoxicity
PR GO:0001815 positive regulation of antibody-dependent cellular cytotoxicity

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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