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GO:0001587 Gq/11-coupled serotonin receptor activity

Term Information

ID GO:0001587
Name Gq/11-coupled serotonin receptor activity
Ontology Molecular Function
Definition Combining with serotonin and transmitting the signal across the membrane by activation of the Gq/11 subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gq/11 subunit subsequently activates phospholipase C and results in an increase in inositol triphosphate (IP3) levels.
PMID:18571247 PMID:18703043
GONUTS GO:0001587 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad 5-HT2 receptor activity
exact serotonin receptor activity, coupled via Gq/11

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0001587:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0001587. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0001587 based on the entire annotation set Co-occurrence statistics for GO:0001587 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-11-16 Added SYNONYM 5-HT2 receptor activity
2011-11-16 Added SYNONYM serotonin receptor activity, coupled via Gq/11
2011-11-16 Added DEFINITION Combining with serotonin and transmitting the signal across the membrane by activation of the Gq/11 subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gq/11 subunit subsequently activates phospholipase C and results in an increase in inositol triphosphate (IP3) levels.
2011-11-16 Updated TERM Gq/11-coupled serotonin receptor activity
2011-11-16 Deleted DEFINITION A serotonin receptor activity that acts via coupling to G11/q to initiate a change in cell activity.
2010-10-07 Added DEFINITION A serotonin receptor activity that acts via coupling to G11/q to initiate a change in cell activity.
2010-06-09 Updated TERM 5-HT2 receptor activity
2010-06-08 Updated TERM 5-HT2 receptor activity
2008-04-01 Updated RELATION is a GO:0004993 (serotonin receptor activity)
2003-03-19 Updated TERM 5-HT2 receptor activity
2002-01-09 Added TERM 5-HT2 receptor

Term

Timestamp Action Category Detail
2011-11-16 Updated TERM Gq/11-coupled serotonin receptor activity
2010-06-09 Updated TERM 5-HT2 receptor activity
2010-06-08 Updated TERM 5-HT2 receptor activity
2003-03-19 Updated TERM 5-HT2 receptor activity
2002-01-09 Added TERM 5-HT2 receptor

Definition/synonyms

Timestamp Action Category Detail
2011-11-16 Added SYNONYM 5-HT2 receptor activity
2011-11-16 Added SYNONYM serotonin receptor activity, coupled via Gq/11
2011-11-16 Added DEFINITION Combining with serotonin and transmitting the signal across the membrane by activation of the Gq/11 subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gq/11 subunit subsequently activates phospholipase C and results in an increase in inositol triphosphate (IP3) levels.
2011-11-16 Deleted DEFINITION A serotonin receptor activity that acts via coupling to G11/q to initiate a change in cell activity.
2010-10-07 Added DEFINITION A serotonin receptor activity that acts via coupling to G11/q to initiate a change in cell activity.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004993 (serotonin receptor activity)
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