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GO:0001308 loss of chromatin silencing during replicative cell aging

The process, which occurs as a dividing cell ages, leading to expression of genes that are typically not expressed due to silencing by regulatory proteins.

Term Information

ID GO:0001308
Name loss of chromatin silencing during replicative cell aging
Ontology Biological Process
Definition The process, which occurs as a dividing cell ages, leading to expression of genes that are typically not expressed due to silencing by regulatory proteins.
Comment

Synonyms

Type Synonym
exact loss of chromatin silencing during replicative cell ageing

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.

Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0008150 biological_process
GO:0016043 cellular component organization
GO:0010926 anatomical structure formation
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0032502 developmental process
GO:0065007 biological regulation
GO:0044085 cellular component biogenesis
GO:0009058 biosynthetic process
GO:0006807 nitrogen compound metabolic process
GO:0050789 regulation of biological process
GO:0044238 primary metabolic process
GO:0007568 aging
GO:0043170 macromolecule metabolic process
GO:0071103 DNA conformation change
GO:0048518 positive regulation of biological process
GO:0043283 biopolymer metabolic process
GO:0048519 negative regulation of biological process
GO:0044237 cellular metabolic process
GO:0006996 organelle organization
GO:0010467 gene expression
GO:0009059 macromolecule biosynthetic process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
GO:0051128 regulation of cellular component organization
GO:0051276 chromosome organization
GO:0022607 cellular component assembly
GO:0006323 DNA packaging
GO:0007569 cell aging
GO:0044087 regulation of cellular component biogenesis
GO:0001302 replicative cell aging
GO:0044260 cellular macromolecule metabolic process
GO:0044249 cellular biosynthetic process
GO:0006325 chromatin organization
GO:0009893 positive regulation of metabolic process
GO:0006333 chromatin assembly or disassembly
GO:0060255 regulation of macromolecule metabolic process
GO:0070828 heterochromatin organization
GO:0009889 regulation of biosynthetic process
GO:0080090 regulation of primary metabolic process
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0043284 biopolymer biosynthetic process
GO:0051171 regulation of nitrogen compound metabolic process
GO:0048523 negative regulation of cellular process
GO:0016568 chromatin modification
GO:0048522 positive regulation of cellular process
GO:0051129 negative regulation of cellular component organization
GO:0009892 negative regulation of metabolic process
GO:0006338 chromatin remodeling
GO:0034960 cellular biopolymer metabolic process
GO:0031323 regulation of cellular metabolic process
GO:0010468 regulation of gene expression
GO:0033043 regulation of organelle organization
GO:0040029 regulation of gene expression, epigenetic
GO:0034645 cellular macromolecule biosynthetic process
GO:0009891 positive regulation of biosynthetic process
GO:0010604 positive regulation of macromolecule metabolic process
GO:0010605 negative regulation of macromolecule metabolic process
GO:0009890 negative regulation of biosynthetic process
GO:0051173 positive regulation of nitrogen compound metabolic process
GO:0051172 negative regulation of nitrogen compound metabolic process
GO:0001301 progressive alteration of chromatin during cell aging
GO:0010556 regulation of macromolecule biosynthetic process
GO:0033044 regulation of chromosome organization
GO:0016070 RNA metabolic process
GO:0010628 positive regulation of gene expression
GO:0031497 chromatin assembly
GO:0010629 negative regulation of gene expression
GO:0031325 positive regulation of cellular metabolic process
GO:0031326 regulation of cellular biosynthetic process
GO:0001304 progressive alteration of chromatin during replicative cell aging
GO:0031324 negative regulation of cellular metabolic process
GO:0010639 negative regulation of organelle organization
GO:0034961 cellular biopolymer biosynthetic process
GO:0001672 regulation of chromatin assembly or disassembly
GO:0032774 RNA biosynthetic process
GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0045814 negative regulation of gene expression, epigenetic
GO:0016458 gene silencing
GO:0045815 positive regulation of gene expression, epigenetic
GO:0010557 positive regulation of macromolecule biosynthetic process
GO:0010558 negative regulation of macromolecule biosynthetic process
GO:0060968 regulation of gene silencing
GO:0031507 heterochromatin formation
GO:0060969 negative regulation of gene silencing
GO:0031327 negative regulation of cellular biosynthetic process
GO:0006350 transcription
GO:0031328 positive regulation of cellular biosynthetic process
GO:0045798 negative regulation of chromatin assembly or disassembly
GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0010847 regulation of chromatin assembly
GO:0006351 transcription, DNA-dependent
GO:0051252 regulation of RNA metabolic process
GO:0031445 regulation of heterochromatin formation
GO:0051254 positive regulation of RNA metabolic process
GO:0051253 negative regulation of RNA metabolic process
GO:0031452 negative regulation of heterochromatin formation
GO:0045449 regulation of transcription
GO:0006355 regulation of transcription, DNA-dependent
GO:0045941 positive regulation of transcription
GO:0016481 negative regulation of transcription
GO:0045893 positive regulation of transcription, DNA-dependent
GO:0045892 negative regulation of transcription, DNA-dependent
GO:0006342 chromatin silencing
GO:0031935 regulation of chromatin silencing
GO:0031936 negative regulation of chromatin silencing
GO:0006345 loss of chromatin silencing
GO:0001308 loss of chromatin silencing during replicative cell aging

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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44ms
Stand-alone
Hostnametomcat-7.ebi.ac.uk
Uptime16:38 12/10/2009
Data version2009-11-24-04-03-40
Terminal
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