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GO:0001106 RNA polymerase II transcription corepressor activity

Term Information

ID GO:0001106
Name RNA polymerase II transcription corepressor activity
Ontology Molecular Function
Definition Interacting selectively and non-covalently with an RNA polymerase II repressing transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
PMID:10213677 PMID:16858867
GONUTS GO:0001106 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact RNA polymerase II transcription co-repressor activity

Cross-references

Database ID
InterPro IPR003994

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0001106:
Relationship To GO:0001106 Child Term Child Term Name
Has part GO:0001103 RNA polymerase II repressing transcription factor binding

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0001106. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0001106 based on the entire annotation set Co-occurrence statistics for GO:0001106 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-08-28 Added RELATION is a GO:0001191 (RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription)
2011-01-23 Added DEFINITION Interacting selectively and non-covalently with an RNA polymerase II repressing transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
2011-01-23 Deleted DEFINITION Interacting selectively and non-covalently with an RNA polymerase II repressing transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the transcription machinery.
2010-12-02 Added RELATION part of GO:0000122 (negative regulation of transcription from RNA polymerase II promoter)
2010-12-02 Added DEFINITION Interacting selectively and non-covalently with an RNA polymerase II repressing transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the transcription machinery.
2010-12-02 Deleted DEFINITION The function of a transcription cofactor that represses transcription from a RNA polymerase II promoter; does not bind DNA itself.
2010-12-01 Added RELATION is a GO:0003714 (transcription corepressor activity)
2010-12-01 Added RELATION is a GO:0001104 (RNA polymerase II transcription cofactor activity)
2010-12-01 Added SYNONYM RNA polymerase II transcription co-repressor activity
2010-12-01 Added DEFINITION The function of a transcription cofactor that represses transcription from a RNA polymerase II promoter; does not bind DNA itself.
2010-12-01 Added TERM RNA polymerase II transcription corepressor activity

Term

Timestamp Action Category Detail
2010-12-01 Added TERM RNA polymerase II transcription corepressor activity

Definition/synonyms

Timestamp Action Category Detail
2011-01-23 Added DEFINITION Interacting selectively and non-covalently with an RNA polymerase II repressing transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
2011-01-23 Deleted DEFINITION Interacting selectively and non-covalently with an RNA polymerase II repressing transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the transcription machinery.
2010-12-02 Added DEFINITION Interacting selectively and non-covalently with an RNA polymerase II repressing transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the transcription machinery.
2010-12-02 Deleted DEFINITION The function of a transcription cofactor that represses transcription from a RNA polymerase II promoter; does not bind DNA itself.
2010-12-01 Added SYNONYM RNA polymerase II transcription co-repressor activity
2010-12-01 Added DEFINITION The function of a transcription cofactor that represses transcription from a RNA polymerase II promoter; does not bind DNA itself.

Relationships

Timestamp Action Category Detail
2011-08-28 Added RELATION is a GO:0001191 (RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription)
2010-12-02 Added RELATION part of GO:0000122 (negative regulation of transcription from RNA polymerase II promoter)
2010-12-01 Added RELATION is a GO:0003714 (transcription corepressor activity)
2010-12-01 Added RELATION is a GO:0001104 (RNA polymerase II transcription cofactor activity)
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