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GO:0001104 RNA polymerase II transcription cofactor activity

Term Information

ID GO:0001104
Name RNA polymerase II transcription cofactor activity
Ontology Molecular Function
Definition Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal RNAP II transcription machinery.
PMID:10213677 PMID:16858867
Secondary IDs GO:0016455
GONUTS GO:0001104 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related thyroid receptor-associated protein
exact RNA polymerase II transcriptional cofactor activity
related TRAP protein
related RNA polymerase II transcription mediator activity
exact RNA polymerase II transcriptional co-regulator

Cross-references

Database ID
InterPro IPR007018
InterPro IPR008626
InterPro IPR008831
InterPro IPR009244
InterPro IPR009332
InterPro IPR009401
InterPro IPR011425
InterPro IPR013921
InterPro IPR013942
InterPro IPR013947
InterPro IPR014801
InterPro IPR016530
InterPro IPR016532
InterPro IPR016612
InterPro IPR016820
InterPro IPR019035
InterPro IPR019087
InterPro IPR019095
InterPro IPR019145
InterPro IPR019258
InterPro IPR019313
InterPro IPR019364
InterPro IPR019403
InterPro IPR019404
InterPro IPR019680
InterPro IPR020998

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0001104:
Relationship To GO:0001104 Child Term Child Term Name
Has part GO:0001099 basal RNA polymerase II transcription machinery binding
Is a GO:0001105 RNA polymerase II transcription coactivator activity
Is a GO:0001106 RNA polymerase II transcription corepressor activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO Term Name
Evidence
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0001104. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0001104 based on the entire annotation set Co-occurrence statistics for GO:0001104 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-05-13 Added SECONDARY GO:0016455 (RNA polymerase II transcription mediator activity)
2011-05-13 Added SYNONYM thyroid receptor-associated protein
2011-05-13 Added SYNONYM RNA polymerase II transcription mediator activity
2011-05-13 Added SYNONYM TRAP protein
2011-01-23 Deleted DEFINITION Interacting selectively and non-covalently with an RNA polymerase II regulatory transcription factor and also with the RNA polymerase II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the transcription machinery.
2011-01-23 Added DEFINITION Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal RNAP II transcription machinery.
2010-12-02 Deleted DEFINITION Interacting selectively and non-covalently with an RNA polymerase II regulatory transcription factor and also with the basal RNA polymerase II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the transcription machinery.
2010-12-02 Added DEFINITION Interacting selectively and non-covalently with an RNA polymerase II regulatory transcription factor and also with the RNA polymerase II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the transcription machinery.
2010-12-01 Added RELATION is a GO:0003712 (transcription cofactor activity)
2010-12-01 Added RELATION is a GO:0001076 (RNA polymerase II transcription factor binding transcription factor activity)
2010-12-01 Added SYNONYM RNA polymerase II transcriptional co-regulator
2010-12-01 Added SYNONYM RNA polymerase II transcriptional cofactor activity
2010-12-01 Added DEFINITION Interacting selectively and non-covalently with an RNA polymerase II regulatory transcription factor and also with the basal RNA polymerase II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the transcription machinery.
2010-12-01 Added TERM RNA polymerase II transcription cofactor activity

Term

Timestamp Action Category Detail
2010-12-01 Added TERM RNA polymerase II transcription cofactor activity

Definition/synonyms

Timestamp Action Category Detail
2011-05-13 Added SYNONYM thyroid receptor-associated protein
2011-05-13 Added SYNONYM RNA polymerase II transcription mediator activity
2011-05-13 Added SYNONYM TRAP protein
2011-01-23 Deleted DEFINITION Interacting selectively and non-covalently with an RNA polymerase II regulatory transcription factor and also with the RNA polymerase II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the transcription machinery.
2011-01-23 Added DEFINITION Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal RNAP II transcription machinery.
2010-12-02 Deleted DEFINITION Interacting selectively and non-covalently with an RNA polymerase II regulatory transcription factor and also with the basal RNA polymerase II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the transcription machinery.
2010-12-02 Added DEFINITION Interacting selectively and non-covalently with an RNA polymerase II regulatory transcription factor and also with the RNA polymerase II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the transcription machinery.
2010-12-01 Added SYNONYM RNA polymerase II transcriptional co-regulator
2010-12-01 Added SYNONYM RNA polymerase II transcriptional cofactor activity
2010-12-01 Added DEFINITION Interacting selectively and non-covalently with an RNA polymerase II regulatory transcription factor and also with the basal RNA polymerase II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the transcription machinery.

Relationships

Timestamp Action Category Detail
2010-12-01 Added RELATION is a GO:0003712 (transcription cofactor activity)
2010-12-01 Added RELATION is a GO:0001076 (RNA polymerase II transcription factor binding transcription factor activity)

Other

Timestamp Action Category Detail
2011-05-13 Added SECONDARY GO:0016455 (RNA polymerase II transcription mediator activity)
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