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GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding

Term Information

ID GO:0000981
Name RNA polymerase II transcription factor activity, sequence-specific DNA binding
Ontology Molecular Function
Definition Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
GONUTS GO:0000981 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact sequence-specific DNA binding RNA polymerase II transcription factor activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to transcription factor activitiesLink

Cross-references

Database ID
InterPro IPR001138
InterPro IPR020448
InterPro IPR027742
InterPro IPR027755
InterPro IPR027757
InterPro IPR027758
InterPro IPR029548
InterPro IPR031265
InterPro IPR032654
InterPro IPR032947
InterPro IPR032949
InterPro IPR033069
InterPro IPR033070
InterPro IPR033287

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0003702 obsolete RNA polymerase II transcription factor activity CONSIDER GO:0000981
GO:0003704 obsolete specific RNA polymerase II transcription factor activity CONSIDER GO:0000981
GO:0016251 obsolete general RNA polymerase II transcription factor activity CONSIDER GO:0000981
GO:0016252 obsolete nonspecific RNA polymerase II transcription factor activity CONSIDER GO:0000981

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000981:
Relationship To GO:0000981 Child Term Child Term Name
Is a GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
Is a GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
Is a GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific
Capable of GO:1990378 upstream stimulatory factor complex
Capable of GO:1990647 C/EBP complex
Is a GO:0001200 RNA polymerase II transcription factor activity, metal ion regulated sequence-specific DNA binding
Is a GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
Is a GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
Is a GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0000981. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0000981 based on the entire annotation set Co-occurrence statistics for GO:0000981 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2015-07-25 Added SYNONYM sequence-specific DNA binding RNA polymerase II transcription factor activity
2015-07-25 Updated TERM RNA polymerase II transcription factor activity, sequence-specific DNA binding
2015-05-19 Deleted RELATION part of GO:0006366 (transcription from RNA polymerase II promoter)
2011-10-13 Added RELATION part of GO:0006357 (regulation of transcription from RNA polymerase II promoter)
2010-10-31 Added RELATION part of GO:0006366 (transcription from RNA polymerase II promoter)
2010-09-03 Added RELATION is a GO:0003700 (transcription factor activity, sequence-specific DNA binding)
2010-09-03 Added DEFINITION Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
2010-09-03 Added TERM sequence-specific DNA binding RNA polymerase II transcription factor activity

Term

Timestamp Action Category Detail
2015-07-25 Updated TERM RNA polymerase II transcription factor activity, sequence-specific DNA binding
2010-09-03 Added TERM sequence-specific DNA binding RNA polymerase II transcription factor activity

Definition/synonyms

Timestamp Action Category Detail
2015-07-25 Added SYNONYM sequence-specific DNA binding RNA polymerase II transcription factor activity
2010-09-03 Added DEFINITION Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.

Relationships

Timestamp Action Category Detail
2015-05-19 Deleted RELATION part of GO:0006366 (transcription from RNA polymerase II promoter)
2011-10-13 Added RELATION part of GO:0006357 (regulation of transcription from RNA polymerase II promoter)
2010-10-31 Added RELATION part of GO:0006366 (transcription from RNA polymerase II promoter)
2010-09-03 Added RELATION is a GO:0003700 (transcription factor activity, sequence-specific DNA binding)
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