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GO:0000954 methionine catabolic process to 3-methylthiopropanoate

Term Information

ID GO:0000954
Name methionine catabolic process to 3-methylthiopropanoate
Ontology Biological Process
Definition The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
PMID:18281432
GONUTS GO:0000954 Wiki Page

Cross-Ontology Relations

Relation Other Ontology ID Term
has_input CHEBI CHEBI:32644 methioninate
has_output CHEBI CHEBI:49016 3-(methylthio)propionate

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000954:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0000954. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0000954 based on the entire annotation set Co-occurrence statistics for GO:0000954 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-11-02 Added RELATION is a GO:0044272 (sulfur compound biosynthetic process)
2012-11-02 Added RELATION is a GO:0006633 (fatty acid biosynthetic process)
2008-05-13 Added DEFINITION The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
2008-04-27 Added DEFINITION The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
2008-04-01 Updated RELATION is a GO:0009087 (methionine catabolic process)
2008-04-01 Updated RELATION is a GO:0000948 (amino acid catabolic process to carboxylic acid via Ehrlich pathway)
2008-03-15 Added TERM methionine catabolic process to 3-methylthiopropanoate

Term

Timestamp Action Category Detail
2008-03-15 Added TERM methionine catabolic process to 3-methylthiopropanoate

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
2008-04-27 Added DEFINITION The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.

Relationships

Timestamp Action Category Detail
2012-11-02 Added RELATION is a GO:0044272 (sulfur compound biosynthetic process)
2012-11-02 Added RELATION is a GO:0006633 (fatty acid biosynthetic process)
2008-04-01 Updated RELATION is a GO:0009087 (methionine catabolic process)
2008-04-01 Updated RELATION is a GO:0000948 (amino acid catabolic process to carboxylic acid via Ehrlich pathway)
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