spacer

GO:0000724 double-strand break repair via homologous recombination

Term Information

ID GO:0000724
Name double-strand break repair via homologous recombination
Ontology Biological Process
Definition The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
PMID:10357855
Secondary IDs GO:0016924
GONUTS GO:0000724 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact homology-directed repair
exact Rhp51-dependent recombinational repair
exact Rad51-dependent recombinational repair
exact homologous recombinational repair
exact HRR
exact HDR

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Guidance for interpreting DNA repair investigationsLink

Cross-references

Database ID
InterPro IPR014140
InterPro IPR015187
InterPro IPR015525
InterPro IPR026846
InterPro IPR027131
InterPro IPR027132
InterPro IPR028730
InterPro IPR029392

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000724:
Relationship To GO:0000724 Child Term Child Term Name
Part of GO:0043150 DNA synthesis involved in double-strand break repair via homologous recombination
Is a GO:0000727 double-strand break repair via break-induced replication
Is a GO:0045003 double-strand break repair via synthesis-dependent strand annealing
Regulates GO:0010569 regulation of double-strand break repair via homologous recombination
Negatively regulates GO:2000042 negative regulation of double-strand break repair via homologous recombination
Is a GO:1990414 replication-born double-strand break repair via sister chromatid exchange

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0000724. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0000724 based on the entire annotation set Co-occurrence statistics for GO:0000724 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2009-10-30 Added SYNONYM homology-directed repair
2009-10-30 Added SYNONYM HDR
2009-02-05 Deleted SYNONYM Rhp51-dependent recombinational repair
2009-02-05 Added SYNONYM Rad51-dependent recombinational repair
2009-02-05 Added SYNONYM Rhp51-dependent recombinational repair
2009-02-01 Added SYNONYM Rhp51-dependent recombinational repair
2009-02-01 Deleted SYNONYM Rad51-dependent recombinational repair
2009-02-01 Deleted SYNONYM Rhp51-dependent recombinational repair
2009-01-31 Deleted SYNONYM Rhp51-dependent recombinational repair
2009-01-31 Added SYNONYM Rad51-dependent recombinational repair
2009-01-31 Added SYNONYM Rhp51-dependent recombinational repair
2008-06-30 Added SYNONYM Rhp51-dependent recombinational repair
2008-05-13 Added DEFINITION The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
2008-05-12 Deleted DEFINITION The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
2008-04-01 Updated RELATION is a GO:0006302 (double-strand break repair)
2008-04-01 Updated RELATION is a GO:0000725 (recombinational repair)
2007-08-09 Added SYNONYM HRR
2007-08-09 Added SYNONYM homologous recombinational repair
2007-08-09 Deleted SYNONYM HRR
2007-08-09 Deleted SYNONYM homologous recombinational repair
2007-01-15 Added SECONDARY GO:0016924 (double-strand break repair via homologous recombination)
2004-07-12 Added SYNONYM homologous recombinational repair
2004-07-12 Added SYNONYM HRR
2003-04-24 Updated DEFINITION The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
2002-11-27 Added DEFINITION The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or non-reciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
2002-09-25 Added TERM double-strand break repair via homologous recombination

Term

Timestamp Action Category Detail
2002-09-25 Added TERM double-strand break repair via homologous recombination

Definition/synonyms

Timestamp Action Category Detail
2009-10-30 Added SYNONYM homology-directed repair
2009-10-30 Added SYNONYM HDR
2009-02-05 Deleted SYNONYM Rhp51-dependent recombinational repair
2009-02-05 Added SYNONYM Rad51-dependent recombinational repair
2009-02-05 Added SYNONYM Rhp51-dependent recombinational repair
2009-02-01 Added SYNONYM Rhp51-dependent recombinational repair
2009-02-01 Deleted SYNONYM Rad51-dependent recombinational repair
2009-02-01 Deleted SYNONYM Rhp51-dependent recombinational repair
2009-01-31 Deleted SYNONYM Rhp51-dependent recombinational repair
2009-01-31 Added SYNONYM Rad51-dependent recombinational repair
2009-01-31 Added SYNONYM Rhp51-dependent recombinational repair
2008-06-30 Added SYNONYM Rhp51-dependent recombinational repair
2008-05-13 Added DEFINITION The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
2008-05-12 Deleted DEFINITION The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
2007-08-09 Added SYNONYM HRR
2007-08-09 Added SYNONYM homologous recombinational repair
2007-08-09 Deleted SYNONYM HRR
2007-08-09 Deleted SYNONYM homologous recombinational repair
2004-07-12 Added SYNONYM homologous recombinational repair
2004-07-12 Added SYNONYM HRR
2003-04-24 Updated DEFINITION The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
2002-11-27 Added DEFINITION The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or non-reciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0006302 (double-strand break repair)
2008-04-01 Updated RELATION is a GO:0000725 (recombinational repair)

Other

Timestamp Action Category Detail
2007-01-15 Added SECONDARY GO:0016924 (double-strand break repair via homologous recombination)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
12ms