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GO:0000398 mRNA splicing, via spliceosome

Term Information

ID GO:0000398
Name mRNA splicing, via spliceosome
Ontology Biological Process
Definition The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
Comment Note that although the many U12-type introns have the sequence AT-AC at the intron termini, some introns with these terminal sequences are spliced by the U2-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron. Note that although the majority of U2-type introns have the sequence GU-AG at the intron termini, some introns with these terminal sequences are spliced by the U12-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron.
Secondary IDs GO:0006374 GO:0006375
GONUTS GO:0000398 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related splicing GT-AG intron
narrow nuclear mRNA splicing via U12-type spliceosome
related splicing AT-AC intron
broad mRNA splicing
exact nuclear mRNA splicing, via spliceosome
broad pre-mRNA splicing
narrow nuclear mRNA splicing via U2-type spliceosome

Cross-references

Database ID
InterPro IPR004015
InterPro IPR006973
InterPro IPR007022
InterPro IPR010491
InterPro IPR012591
InterPro IPR012592
InterPro IPR017340
InterPro IPR017862
InterPro IPR024667
InterPro IPR024888
InterPro IPR026300
InterPro IPR027078
InterPro IPR027104
InterPro IPR027105
InterPro IPR027108
InterPro IPR027652
InterPro IPR029536

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0006371 mRNA splicing CONSIDER GO:0000398

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000398:
Relationship To GO:0000398 Child Term Child Term Name
Part of GO:0000245 spliceosomal complex assembly
Part of GO:0000387 spliceosomal snRNP assembly
Part of GO:0000390 spliceosomal complex disassembly
Part of GO:0000393 spliceosomal conformational changes to generate catalytic conformation
Is a GO:0000365 mRNA trans splicing, via spliceosome
Is a GO:0045292 mRNA cis splicing, via spliceosome
Regulates GO:0048024 regulation of mRNA splicing, via spliceosome
Negatively regulates GO:0048025 negative regulation of mRNA splicing, via spliceosome
Positively regulates GO:0048026 positive regulation of mRNA splicing, via spliceosome
Is a GO:0000380 alternative mRNA splicing, via spliceosome

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0000398. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0000398 based on the entire annotation set Co-occurrence statistics for GO:0000398 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2012-09-14 Updated TERM mRNA splicing, via spliceosome
2012-09-14 Deleted DEFINITION The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
2012-09-14 Added DEFINITION The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
2012-09-14 Added SYNONYM nuclear mRNA splicing, via spliceosome
2008-05-13 Added DEFINITION The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
2008-05-12 Deleted DEFINITION The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
2008-05-09 Added SECONDARY GO:0006375 (nuclear mRNA splicing via U12-type spliceosome)
2008-05-09 Added SECONDARY GO:0006374 (nuclear mRNA splicing via U2-type spliceosome)
2008-05-09 Added SYNONYM nuclear mRNA splicing via U12-type spliceosome
2008-05-09 Added SYNONYM nuclear mRNA splicing via U2-type spliceosome
2008-05-09 Added SYNONYM splicing AT-AC intron
2008-05-09 Added SYNONYM splicing GT-AG intron
2008-04-01 Updated RELATION is a GO:0006397 (mRNA processing)
2008-04-01 Updated RELATION is a GO:0000377 (RNA splicing, via transesterification reactions with bulged adenosine as nucleophile)
2007-08-09 Added SYNONYM mRNA splicing
2007-08-09 Added SYNONYM pre-mRNA splicing
2007-08-09 Deleted SYNONYM mRNA splicing
2007-08-09 Deleted SYNONYM pre-mRNA splicing
2004-04-19 Added SYNONYM mRNA splicing
2004-04-19 Added SYNONYM pre-mRNA splicing
2004-04-16 Deleted SYNONYM mRNA splicing
2004-04-16 Deleted SYNONYM pre-mRNA splicing
2003-09-04 Added SYNONYM mRNA splicing
2003-09-04 Added SYNONYM pre-mRNA splicing
2003-09-04 Added DEFINITION The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
2003-09-04 Added TERM nuclear mRNA splicing, via spliceosome

Term

Timestamp Action Category Detail
2012-09-14 Updated TERM mRNA splicing, via spliceosome
2003-09-04 Added TERM nuclear mRNA splicing, via spliceosome

Definition/synonyms

Timestamp Action Category Detail
2012-09-14 Deleted DEFINITION The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
2012-09-14 Added DEFINITION The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
2012-09-14 Added SYNONYM nuclear mRNA splicing, via spliceosome
2008-05-13 Added DEFINITION The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
2008-05-12 Deleted DEFINITION The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
2008-05-09 Added SYNONYM nuclear mRNA splicing via U12-type spliceosome
2008-05-09 Added SYNONYM nuclear mRNA splicing via U2-type spliceosome
2008-05-09 Added SYNONYM splicing AT-AC intron
2008-05-09 Added SYNONYM splicing GT-AG intron
2007-08-09 Added SYNONYM mRNA splicing
2007-08-09 Added SYNONYM pre-mRNA splicing
2007-08-09 Deleted SYNONYM mRNA splicing
2007-08-09 Deleted SYNONYM pre-mRNA splicing
2004-04-19 Added SYNONYM mRNA splicing
2004-04-19 Added SYNONYM pre-mRNA splicing
2004-04-16 Deleted SYNONYM mRNA splicing
2004-04-16 Deleted SYNONYM pre-mRNA splicing
2003-09-04 Added SYNONYM mRNA splicing
2003-09-04 Added SYNONYM pre-mRNA splicing
2003-09-04 Added DEFINITION The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0006397 (mRNA processing)
2008-04-01 Updated RELATION is a GO:0000377 (RNA splicing, via transesterification reactions with bulged adenosine as nucleophile)

Other

Timestamp Action Category Detail
2008-05-09 Added SECONDARY GO:0006375 (nuclear mRNA splicing via U12-type spliceosome)
2008-05-09 Added SECONDARY GO:0006374 (nuclear mRNA splicing via U2-type spliceosome)
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