spacer

GO:0000375 RNA splicing, via transesterification reactions

Term Information

ID GO:0000375
Name RNA splicing, via transesterification reactions
Ontology Biological Process
Definition Splicing of RNA via a series of two transesterification reactions.
Comment Note that nuclear mRNA, Group I, Group II, and Group III introns are all spliced by a series of two transesterification reactions that occur within the RNA itself, or between two RNAs in trans splicing. Some of these require one or more proteins to stabilize the catalytic conformation, while others are autocatalytic. Note that tRNA introns are spliced by a different catalytic mechanism.
Secondary IDs GO:0000385 GO:0031202
GONUTS GO:0000375 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related spliceosomal catalysis
related RNA splicing factor activity, transesterification mechanism
related pre-mRNA splicing factor activity

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0005570 small nuclear RNA CONSIDER GO:0000375

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000375:
Relationship To GO:0000375 Child Term Child Term Name
Part of GO:0000384 first spliceosomal transesterification activity
Part of GO:0000386 second spliceosomal transesterification activity
Is a GO:0000376 RNA splicing, via transesterification reactions with guanosine as nucleophile
Is a GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0000375. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0000375 based on the entire annotation set Co-occurrence statistics for GO:0000375 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2009-11-05 Added SYNONYM RNA splicing factor activity, transesterification mechanism
2009-11-05 Added SYNONYM spliceosomal catalysis
2009-11-05 Added SECONDARY GO:0031202 (RNA splicing factor activity, transesterification mechanism)
2009-11-05 Added SECONDARY GO:0000385 (spliceosomal catalysis)
2009-11-05 Added SYNONYM pre-mRNA splicing factor activity
2008-05-13 Added DEFINITION Splicing of RNA via a series of two transesterification reactions.
2008-05-12 Deleted DEFINITION Splicing of RNA via a series of two transesterification reactions.
2008-04-01 Updated RELATION is a GO:0008380 (RNA splicing)
2003-08-22 Added DEFINITION Splicing of RNA via a series of two transesterification reactions.
2003-08-21 Added TERM RNA splicing, via transesterification reactions

Term

Timestamp Action Category Detail
2003-08-21 Added TERM RNA splicing, via transesterification reactions

Definition/synonyms

Timestamp Action Category Detail
2009-11-05 Added SYNONYM RNA splicing factor activity, transesterification mechanism
2009-11-05 Added SYNONYM spliceosomal catalysis
2009-11-05 Added SYNONYM pre-mRNA splicing factor activity
2008-05-13 Added DEFINITION Splicing of RNA via a series of two transesterification reactions.
2008-05-12 Deleted DEFINITION Splicing of RNA via a series of two transesterification reactions.
2003-08-22 Added DEFINITION Splicing of RNA via a series of two transesterification reactions.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0008380 (RNA splicing)

Other

Timestamp Action Category Detail
2009-11-05 Added SECONDARY GO:0031202 (RNA splicing factor activity, transesterification mechanism)
2009-11-05 Added SECONDARY GO:0000385 (spliceosomal catalysis)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
29ms