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GO:0000354 cis assembly of pre-catalytic spliceosome

Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.

Term Information

ID GO:0000354
Name cis assembly of pre-catalytic spliceosome
Ontology Biological Process
Definition Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.
Comment Note that this step represents formation of the A2-1 complex (yeast) or the B1 complex (mammals).

Synonyms

Type Synonym
narrow formation of spliceosomal A2-1 complex
narrow spliceosomal A2-1 complex biosynthesis
narrow cis assembly of U2-type pre-catalytic spliceosome
narrow spliceosomal A2-1 complex formation
narrow formation of spliceosomal B1 complex
narrow spliceosomal B1 complex formation
narrow cis assembly of U12-type pre-catalytic spliceosome
narrow spliceosomal B1 complex biosynthesis

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Ancestor Table

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0010926 anatomical structure formation
GO:0016043 cellular component organization
GO:0008152 metabolic process
GO:0044085 cellular component biogenesis
GO:0044238 primary metabolic process
GO:0043170 macromolecule metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0043933 macromolecular complex subunit organization
GO:0043283 biopolymer metabolic process
GO:0044237 cellular metabolic process
GO:0022613 ribonucleoprotein complex biogenesis
GO:0010467 gene expression
GO:0034621 cellular macromolecular complex subunit organization
GO:0022607 cellular component assembly
GO:0044260 cellular macromolecule metabolic process
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0065003 macromolecular complex assembly
GO:0034960 cellular biopolymer metabolic process
GO:0034622 cellular macromolecular complex assembly
GO:0016070 RNA metabolic process
GO:0022618 ribonucleoprotein complex assembly
GO:0016071 mRNA metabolic process
GO:0006396 RNA processing
GO:0008380 RNA splicing
GO:0000375 RNA splicing, via transesterification reactions
GO:0006397 mRNA processing
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
GO:0000398 nuclear mRNA splicing, via spliceosome
GO:0045292 nuclear mRNA cis splicing, via spliceosome
GO:0000245 spliceosome assembly
GO:0000354 cis assembly of pre-catalytic spliceosome

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

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Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Co-occurring Terms

Co-occurrence statistics

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