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GO:0000293 ferric-chelate reductase activity

Term Information

ID GO:0000293
Name ferric-chelate reductase activity
Ontology Molecular Function
Definition Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H(+).
Comment Note that this function was formerly EC:1.6.99.13.
GONUTS GO:0000293 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related iron chelate reductase activity
exact ferric chelate reductase activity
exact NADH:Fe(3+)-EDTA reductase activity
exact NADH:Fe(3+) oxidoreductase activity
exact NADH:Fe3+ oxidoreductase activity
exact Fe(II):NAD+ oxidoreductase activity
exact NADH2:Fe3+ oxidoreductase activity
exact NADH:Fe3+-EDTA reductase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.16.1.7
InterPro IPR028837
InterPro IPR028838
InterPro IPR030155
MetaCyc FERRIC-CHELATE-REDUCTASE-RXN
RHEA 15064

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000293:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0000293. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0000293 based on the entire annotation set Co-occurrence statistics for GO:0000293 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-10-10 Added RELATION has part GO:0033215 (iron assimilation by reduction and transport)
2011-09-16 Added XREF RHEA:15064
2011-09-16 Added DEFINITION Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H(+).
2011-09-16 Deleted DEFINITION Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H+.
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H+.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H+.
2008-04-01 Updated RELATION is a GO:0016723 (oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor)
2007-11-08 Added SYNONYM Fe(II):NAD+ oxidoreductase activity
2007-11-08 Added SYNONYM NADH2:Fe3+ oxidoreductase activity
2007-11-08 Added SYNONYM NADH:Fe3+ oxidoreductase activity
2007-11-08 Added SYNONYM NADH:Fe3+-EDTA reductase activity
2007-09-06 Added SYNONYM NADH:Fe(3+) oxidoreductase activity
2007-09-06 Added SYNONYM NADH:Fe(3+)-EDTA reductase activity
2007-09-06 Added SYNONYM ferric chelate reductase activity
2007-09-06 Added SYNONYM iron chelate reductase activity
2006-02-04 Updated DEFINITION Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H+.
2003-10-27 Added XREF MetaCyc:FERRIC-CHELATE-REDUCTASE-RXN
2003-03-26 Updated DEFINITION Catalysis of the reaction: 2 Fe(II) + NAD+ = 2 Fe(III) + NADH + H+.
2003-03-19 Updated TERM ferric-chelate reductase activity
2002-12-20 Deleted XREF EC:1.6.99.13
2002-12-19 Added XREF EC:1.16.1.7
2002-11-27 Added DEFINITION Reduces iron(FeIII)-containing siderophores.
2002-03-17 Added XREF EC:1.6.99.13
2002-03-17 Added TERM ferric-chelate reductase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM ferric-chelate reductase activity
2002-03-17 Added TERM ferric-chelate reductase

Definition/synonyms

Timestamp Action Category Detail
2011-09-16 Added DEFINITION Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H(+).
2011-09-16 Deleted DEFINITION Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H+.
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H+.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H+.
2007-11-08 Added SYNONYM Fe(II):NAD+ oxidoreductase activity
2007-11-08 Added SYNONYM NADH2:Fe3+ oxidoreductase activity
2007-11-08 Added SYNONYM NADH:Fe3+ oxidoreductase activity
2007-11-08 Added SYNONYM NADH:Fe3+-EDTA reductase activity
2007-09-06 Added SYNONYM NADH:Fe(3+) oxidoreductase activity
2007-09-06 Added SYNONYM NADH:Fe(3+)-EDTA reductase activity
2007-09-06 Added SYNONYM ferric chelate reductase activity
2007-09-06 Added SYNONYM iron chelate reductase activity
2006-02-04 Updated DEFINITION Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H+.
2003-03-26 Updated DEFINITION Catalysis of the reaction: 2 Fe(II) + NAD+ = 2 Fe(III) + NADH + H+.
2002-11-27 Added DEFINITION Reduces iron(FeIII)-containing siderophores.

Relationships

Timestamp Action Category Detail
2013-10-10 Added RELATION has part GO:0033215 (iron assimilation by reduction and transport)
2008-04-01 Updated RELATION is a GO:0016723 (oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor)

Cross-references

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:15064
2003-10-27 Added XREF MetaCyc:FERRIC-CHELATE-REDUCTASE-RXN
2002-12-20 Deleted XREF EC:1.6.99.13
2002-12-19 Added XREF EC:1.16.1.7
2002-03-17 Added XREF EC:1.6.99.13
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