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GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.

Term Information

ID GO:0000288
Name nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
Ontology Biological Process
Definition A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.
Comment

Synonyms

Type Synonym
exact nuclear mRNA catabolic process, deadenylation-dependent decay
exact mRNA degradation, deadenylation-dependent decay
exact mRNA catabolism, deadenylation-dependent
exact mRNA catabolism, deadenylylation-dependent
exact mRNA catabolic process, deadenylylation-dependent
exact deadenylation-dependent mRNA decay
exact mRNA breakdown, deadenylation-dependent decay
exact mRNA catabolic process, deadenylation-dependent

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0044238 primary metabolic process
GO:0009056 catabolic process
GO:0043170 macromolecule metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0043283 biopolymer metabolic process
GO:0044237 cellular metabolic process
GO:0009057 macromolecule catabolic process
GO:0044260 cellular macromolecule metabolic process
GO:0044248 cellular catabolic process
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0043285 biopolymer catabolic process
GO:0034960 cellular biopolymer metabolic process
GO:0044265 cellular macromolecule catabolic process
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
GO:0034962 cellular biopolymer catabolic process
GO:0006401 RNA catabolic process
GO:0006402 mRNA catabolic process
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
P GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening
P GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA
P GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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