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GO:0000225 N-acetylglucosaminylphosphatidylinositol deacetylase activity

Term Information

ID GO:0000225
Name N-acetylglucosaminylphosphatidylinositol deacetylase activity
Ontology Molecular Function
Definition Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane.
Comment Note that this function was formerly EC:3.1.1.69.
GONUTS GO:0000225 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase activity
exact acetylglucosaminylphosphatidylinositol deacetylase activity
exact N-acetylglucosaminylphosphatidylinositol de-N-acetylase activity
exact N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase activity
exact GlcNAc-PI deacetylase activity
exact GlcNAc-PI de-N-acetylase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 3.5.1.89
MetaCyc 3.1.1.69-RXN
RHEA 11663

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000225:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0000225. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0000225 based on the entire annotation set Co-occurrence statistics for GO:0000225 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:11663
2010-09-03 Deleted DEFINITION Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. The second step enzyme catalyzing the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane. Catalyzes the N-deacetylation of GlcNAc-PI to GlcN-PI.
2010-09-03 Added DEFINITION Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane.
2008-05-13 Added DEFINITION Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. The second step enzyme catalyzing the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane. Catalyzes the N-deacetylation of GlcNAc-PI to GlcN-PI.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. The second step enzyme catalyzing the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane. Catalyzes the N-deacetylation of GlcNAc-PI to GlcN-PI.
2008-04-01 Updated RELATION is a GO:0019213 (deacetylase activity)
2008-04-01 Updated RELATION is a GO:0016811 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides)
2007-11-08 Added SYNONYM 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase activity
2007-09-06 Added SYNONYM GlcNAc-PI de-N-acetylase activity
2007-09-06 Added SYNONYM GlcNAc-PI deacetylase activity
2007-09-06 Added SYNONYM N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase activity
2007-09-06 Added SYNONYM N-acetylglucosaminylphosphatidylinositol de-N-acetylase activity
2007-09-06 Added SYNONYM acetylglucosaminylphosphatidylinositol deacetylase activity
2003-10-27 Added XREF MetaCyc:3.1.1.69-RXN
2003-09-05 Added XREF EC:3.5.1.89
2003-09-05 Deleted XREF EC:3.1.1.69
2003-03-19 Updated TERM N-acetylglucosaminylphosphatidylinositol deacetylase activity
2002-11-27 Updated DEFINITION Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. The second step enzyme catalyzing the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane. Catalyzes the N-deacetylation of GlcNAc-PI to GlcN-PI.
2002-02-06 Updated TERM N-acetylglucosaminylphosphatidylinositol deacetylase
2001-08-06 Added DEFINITION The second step enzyme catalyzing the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane. Catalyzes the de-N-acetylation of GlcNAc-PI to GlcN-PI.
2001-04-03 Updated TERM N-acetylglucosaminylphosphatidylinositol deacetylase
2001-03-30 Added XREF EC:3.1.1.69
2001-03-30 Added TERM N-acetylglucosaminylphosphatidylinositol deacetylase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM N-acetylglucosaminylphosphatidylinositol deacetylase activity
2002-02-06 Updated TERM N-acetylglucosaminylphosphatidylinositol deacetylase
2001-04-03 Updated TERM N-acetylglucosaminylphosphatidylinositol deacetylase
2001-03-30 Added TERM N-acetylglucosaminylphosphatidylinositol deacetylase

Definition/synonyms

Timestamp Action Category Detail
2010-09-03 Deleted DEFINITION Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. The second step enzyme catalyzing the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane. Catalyzes the N-deacetylation of GlcNAc-PI to GlcN-PI.
2010-09-03 Added DEFINITION Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane.
2008-05-13 Added DEFINITION Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. The second step enzyme catalyzing the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane. Catalyzes the N-deacetylation of GlcNAc-PI to GlcN-PI.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. The second step enzyme catalyzing the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane. Catalyzes the N-deacetylation of GlcNAc-PI to GlcN-PI.
2007-11-08 Added SYNONYM 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase activity
2007-09-06 Added SYNONYM GlcNAc-PI de-N-acetylase activity
2007-09-06 Added SYNONYM GlcNAc-PI deacetylase activity
2007-09-06 Added SYNONYM N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase activity
2007-09-06 Added SYNONYM N-acetylglucosaminylphosphatidylinositol de-N-acetylase activity
2007-09-06 Added SYNONYM acetylglucosaminylphosphatidylinositol deacetylase activity
2002-11-27 Updated DEFINITION Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. The second step enzyme catalyzing the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane. Catalyzes the N-deacetylation of GlcNAc-PI to GlcN-PI.
2001-08-06 Added DEFINITION The second step enzyme catalyzing the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane. Catalyzes the de-N-acetylation of GlcNAc-PI to GlcN-PI.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0019213 (deacetylase activity)
2008-04-01 Updated RELATION is a GO:0016811 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides)

Cross-references

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:11663
2003-10-27 Added XREF MetaCyc:3.1.1.69-RXN
2003-09-05 Added XREF EC:3.5.1.89
2003-09-05 Deleted XREF EC:3.1.1.69
2001-03-30 Added XREF EC:3.1.1.69
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