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GO:0000186 activation of MAPKK activity

Term Information

ID GO:0000186
Name activation of MAPKK activity
Ontology Biological Process
Definition The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK).
PMID:9561267
Secondary IDs GO:0007255
GONUTS GO:0000186 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact activation of MAP kinase kinase activity
narrow activation of MAPKK activity during sporulation
exact activation of MAP2K activity
exact activation of MAP/ERK kinase kinase
broad positive regulation of MAPKK activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Describing enzyme functions that catalyse multi-stage reactionsLink

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000017 GO:0000186 activation of MAPKK activity only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR009106
InterPro IPR017419
InterPro IPR027257
InterPro IPR027258

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000186:
Relationship To GO:0000186 Child Term Child Term Name
Is a GO:0000168 activation of MAPKK activity involved in osmosensory signaling pathway
Is a GO:0000198 activation of MAPKK activity involved in cell wall organization or biogenesis
Is a GO:0007256 activation of JNKK activity
Is a GO:0071509 activation of MAPKK activity involved in conjugation with cellular fusion
Is a GO:0035421 activation of MAPKK activity involved in innate immune response
Part of GO:0004709 MAP kinase kinase kinase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
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Date
Assigned By
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Name
Synonym
Type
Taxon Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0000186. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0000186 based on the entire annotation set Co-occurrence statistics for GO:0000186 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-05-30 Deleted DEFINITION The initiation of the activity of the inactive enzyme MAP kinase kinase by phosphorylation by a MAPKKK.
2013-05-30 Added DEFINITION The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK).
2013-05-30 Deleted RELATION is a GO:0006468 (protein phosphorylation)
2012-10-29 Added RELATION is a GO:0043408 (regulation of MAPK cascade)
2012-01-29 Deleted RELATION part of GO:0000165 (MAPK cascade)
2012-01-29 Added SYNONYM activation of MAP2K activity
2012-01-22 Added RELATION positively regulates GO:0004708 (MAP kinase kinase activity)
2009-06-11 Deleted SYNONYM activation of MAPKK during sporulation (sensu Fungi)
2009-06-11 Deleted SYNONYM activation of MAPKK during sporulation (sensu Saccharomyces)
2009-06-11 Added SYNONYM activation of MAPKK activity during sporulation
2009-02-25 Updated TERM activation of MAPKK activity
2009-02-22 Updated TERM activation of MAPKK activity
2008-05-13 Added DEFINITION The initiation of the activity of the inactive enzyme MAP kinase kinase by phosphorylation by a MAPKKK.
2008-05-12 Deleted DEFINITION The initiation of the activity of the inactive enzyme MAP kinase kinase by phosphorylation by a MAPKKK.
2008-04-01 Updated RELATION is a GO:0006468 (protein phosphorylation)
2008-04-01 Updated RELATION is a GO:0032147 (activation of protein kinase activity)
2008-04-01 Updated RELATION part of GO:0000165 (MAPK cascade)
2007-08-09 Added SYNONYM activation of MAP/ERK kinase kinase
2007-08-09 Added SYNONYM activation of MAPKK during sporulation (sensu Fungi)
2007-08-09 Added SYNONYM activation of MAPKK during sporulation (sensu Saccharomyces)
2007-08-09 Added SYNONYM positive regulation of MAPKK activity
2007-08-09 Added SYNONYM activation of MAP kinase kinase activity
2007-08-09 Deleted SYNONYM activation of MAPKK during sporulation (sensu Fungi)
2007-08-09 Deleted SYNONYM activation of MAPKK during sporulation (sensu Saccharomyces)
2007-08-09 Deleted SYNONYM activation of MAP kinase kinase activity
2007-08-09 Deleted SYNONYM activation of MAP/ERK kinase kinase
2007-08-09 Deleted SYNONYM positive regulation of MAPKK activity
2007-04-21 Added SYNONYM activation of MAPKK during sporulation (sensu Fungi)
2007-04-21 Added SYNONYM activation of MAPKK during sporulation (sensu Saccharomyces)
2005-06-27 Added SYNONYM activation of MAP kinase kinase activity
2005-06-27 Updated TERM activation of MAPKK activity
2005-06-24 Updated DEFINITION The initiation of the activity of the inactive enzyme MAP kinase kinase by phosphorylation by a MAPKKK.
2004-07-31 Added SYNONYM positive regulation of MAPKK activity
2004-07-30 Added SECONDARY GO:0007255 (activation of MAP/ERK kinase kinase)
2004-07-30 Added SYNONYM activation of MAP/ERK kinase kinase
2002-02-06 Updated TERM activation of MAPKK
2001-08-06 Added DEFINITION Upregulation of a MAP kinase kinase due to phosphorylation by a MAPKKK.
2001-04-03 Updated TERM activation of MAPKK
2001-03-30 Added TERM activation of MAPKK

Term

Timestamp Action Category Detail
2009-02-25 Updated TERM activation of MAPKK activity
2009-02-22 Updated TERM activation of MAPKK activity
2005-06-27 Updated TERM activation of MAPKK activity
2002-02-06 Updated TERM activation of MAPKK
2001-04-03 Updated TERM activation of MAPKK
2001-03-30 Added TERM activation of MAPKK

Definition/synonyms

Timestamp Action Category Detail
2013-05-30 Deleted DEFINITION The initiation of the activity of the inactive enzyme MAP kinase kinase by phosphorylation by a MAPKKK.
2013-05-30 Added DEFINITION The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK).
2012-01-29 Added SYNONYM activation of MAP2K activity
2009-06-11 Deleted SYNONYM activation of MAPKK during sporulation (sensu Fungi)
2009-06-11 Deleted SYNONYM activation of MAPKK during sporulation (sensu Saccharomyces)
2009-06-11 Added SYNONYM activation of MAPKK activity during sporulation
2008-05-13 Added DEFINITION The initiation of the activity of the inactive enzyme MAP kinase kinase by phosphorylation by a MAPKKK.
2008-05-12 Deleted DEFINITION The initiation of the activity of the inactive enzyme MAP kinase kinase by phosphorylation by a MAPKKK.
2007-08-09 Added SYNONYM activation of MAP/ERK kinase kinase
2007-08-09 Added SYNONYM activation of MAPKK during sporulation (sensu Fungi)
2007-08-09 Added SYNONYM activation of MAPKK during sporulation (sensu Saccharomyces)
2007-08-09 Added SYNONYM positive regulation of MAPKK activity
2007-08-09 Added SYNONYM activation of MAP kinase kinase activity
2007-08-09 Deleted SYNONYM activation of MAPKK during sporulation (sensu Fungi)
2007-08-09 Deleted SYNONYM activation of MAPKK during sporulation (sensu Saccharomyces)
2007-08-09 Deleted SYNONYM activation of MAP kinase kinase activity
2007-08-09 Deleted SYNONYM activation of MAP/ERK kinase kinase
2007-08-09 Deleted SYNONYM positive regulation of MAPKK activity
2007-04-21 Added SYNONYM activation of MAPKK during sporulation (sensu Fungi)
2007-04-21 Added SYNONYM activation of MAPKK during sporulation (sensu Saccharomyces)
2005-06-27 Added SYNONYM activation of MAP kinase kinase activity
2005-06-24 Updated DEFINITION The initiation of the activity of the inactive enzyme MAP kinase kinase by phosphorylation by a MAPKKK.
2004-07-31 Added SYNONYM positive regulation of MAPKK activity
2004-07-30 Added SYNONYM activation of MAP/ERK kinase kinase
2001-08-06 Added DEFINITION Upregulation of a MAP kinase kinase due to phosphorylation by a MAPKKK.

Relationships

Timestamp Action Category Detail
2013-05-30 Deleted RELATION is a GO:0006468 (protein phosphorylation)
2012-10-29 Added RELATION is a GO:0043408 (regulation of MAPK cascade)
2012-01-29 Deleted RELATION part of GO:0000165 (MAPK cascade)
2012-01-22 Added RELATION positively regulates GO:0004708 (MAP kinase kinase activity)
2008-04-01 Updated RELATION is a GO:0006468 (protein phosphorylation)
2008-04-01 Updated RELATION is a GO:0032147 (activation of protein kinase activity)
2008-04-01 Updated RELATION part of GO:0000165 (MAPK cascade)

Other

Timestamp Action Category Detail
2004-07-30 Added SECONDARY GO:0007255 (activation of MAP/ERK kinase kinase)
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