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GO:0000185 activation of MAPKKK activity

Term Information

ID GO:0000185
Name activation of MAPKKK activity
Ontology Biological Process
Definition Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK).
PMID:9561267
GONUTS GO:0000185 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow activation of MAPKKK activity during sporulation
exact activation of MAP3K activity
broad positive regulation of MAPKKK activity
broad positive regulation of MAP kinase kinase kinase activity
exact activation of MAP kinase kinase kinase

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Describing enzyme functions that catalyse multi-stage reactionsLink

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000016 GO:0000185 activation of MAPKKK activity only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000185:
Relationship To GO:0000185 Child Term Child Term Name
Is a GO:0000167 activation of MAPKKK activity involved in osmosensory signaling pathway
Is a GO:0000197 activation of MAPKKK activity involved in cell wall organization or biogenesis
Is a GO:0042655 activation of JNKKK activity
Is a GO:0071510 activation of MAPKKK activity involved in conjugation with cellular fusion
Is a GO:0035422 activation of MAPKKK activity involved in innate immune response
Part of GO:0008349 MAP kinase kinase kinase kinase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO ID
Original GO Term Name
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Name
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Taxon Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0000185. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0000185 based on the entire annotation set Co-occurrence statistics for GO:0000185 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-05-30 Deleted DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase.
2013-05-30 Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK).
2012-10-29 Added RELATION is a GO:0071902 (positive regulation of protein serine/threonine kinase activity)
2012-10-29 Added RELATION is a GO:0043408 (regulation of MAPK cascade)
2012-01-29 Deleted RELATION part of GO:0043410 (positive regulation of MAPK cascade)
2012-01-29 Added SYNONYM activation of MAP3K activity
2012-01-22 Added RELATION positively regulates GO:0004709 (MAP kinase kinase kinase activity)
2011-05-12 Added RELATION part of GO:0043410 (positive regulation of MAPK cascade)
2011-05-12 Deleted RELATION part of GO:0000165 (MAPK cascade)
2009-06-11 Deleted SYNONYM activation of MAPKKK during sporulation (sensu Fungi)
2009-06-11 Deleted SYNONYM activation of MAPKKK during sporulation (sensu Saccharomyces)
2009-06-11 Added SYNONYM activation of MAPKKK activity during sporulation
2009-02-25 Updated TERM activation of MAPKKK activity
2009-02-22 Updated TERM activation of MAPKKK activity
2008-05-13 Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase.
2008-05-12 Deleted DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase.
2008-04-01 Updated RELATION is a GO:0032147 (activation of protein kinase activity)
2008-04-01 Updated RELATION part of GO:0000165 (MAPK cascade)
2007-08-09 Added SYNONYM activation of MAP kinase kinase kinase
2007-08-09 Added SYNONYM activation of MAPKKK during sporulation (sensu Fungi)
2007-08-09 Added SYNONYM activation of MAPKKK during sporulation (sensu Saccharomyces)
2007-08-09 Added SYNONYM positive regulation of MAP kinase kinase kinase activity
2007-08-09 Added SYNONYM positive regulation of MAPKKK activity
2007-08-09 Deleted SYNONYM activation of MAPKKK during sporulation (sensu Fungi)
2007-08-09 Deleted SYNONYM activation of MAPKKK during sporulation (sensu Saccharomyces)
2007-08-09 Deleted SYNONYM activation of MAP kinase kinase kinase
2007-08-09 Deleted SYNONYM positive regulation of MAP kinase kinase kinase activity
2007-08-09 Deleted SYNONYM positive regulation of MAPKKK activity
2007-04-21 Added SYNONYM activation of MAPKKK during sporulation (sensu Fungi)
2007-04-21 Added SYNONYM activation of MAPKKK during sporulation (sensu Saccharomyces)
2005-06-27 Updated TERM activation of MAPKKK activity
2005-06-24 Updated DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase.
2004-07-31 Added SYNONYM activation of MAP kinase kinase kinase
2004-07-31 Added SYNONYM positive regulation of MAP kinase kinase kinase activity
2004-07-31 Added SYNONYM positive regulation of MAPKKK activity
2002-02-06 Updated TERM activation of MAPKKK
2001-08-06 Added DEFINITION Upregulation of MAPKKK activity in response to a signal.
2001-04-03 Updated TERM activation of MAPKKK
2001-03-30 Added TERM activation of MAPKKK

Term

Timestamp Action Category Detail
2009-02-25 Updated TERM activation of MAPKKK activity
2009-02-22 Updated TERM activation of MAPKKK activity
2005-06-27 Updated TERM activation of MAPKKK activity
2002-02-06 Updated TERM activation of MAPKKK
2001-04-03 Updated TERM activation of MAPKKK
2001-03-30 Added TERM activation of MAPKKK

Definition/synonyms

Timestamp Action Category Detail
2013-05-30 Deleted DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase.
2013-05-30 Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK).
2012-01-29 Added SYNONYM activation of MAP3K activity
2009-06-11 Deleted SYNONYM activation of MAPKKK during sporulation (sensu Fungi)
2009-06-11 Deleted SYNONYM activation of MAPKKK during sporulation (sensu Saccharomyces)
2009-06-11 Added SYNONYM activation of MAPKKK activity during sporulation
2008-05-13 Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase.
2008-05-12 Deleted DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase.
2007-08-09 Added SYNONYM activation of MAP kinase kinase kinase
2007-08-09 Added SYNONYM activation of MAPKKK during sporulation (sensu Fungi)
2007-08-09 Added SYNONYM activation of MAPKKK during sporulation (sensu Saccharomyces)
2007-08-09 Added SYNONYM positive regulation of MAP kinase kinase kinase activity
2007-08-09 Added SYNONYM positive regulation of MAPKKK activity
2007-08-09 Deleted SYNONYM activation of MAPKKK during sporulation (sensu Fungi)
2007-08-09 Deleted SYNONYM activation of MAPKKK during sporulation (sensu Saccharomyces)
2007-08-09 Deleted SYNONYM activation of MAP kinase kinase kinase
2007-08-09 Deleted SYNONYM positive regulation of MAP kinase kinase kinase activity
2007-08-09 Deleted SYNONYM positive regulation of MAPKKK activity
2007-04-21 Added SYNONYM activation of MAPKKK during sporulation (sensu Fungi)
2007-04-21 Added SYNONYM activation of MAPKKK during sporulation (sensu Saccharomyces)
2005-06-24 Updated DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase.
2004-07-31 Added SYNONYM activation of MAP kinase kinase kinase
2004-07-31 Added SYNONYM positive regulation of MAP kinase kinase kinase activity
2004-07-31 Added SYNONYM positive regulation of MAPKKK activity
2001-08-06 Added DEFINITION Upregulation of MAPKKK activity in response to a signal.

Relationships

Timestamp Action Category Detail
2012-10-29 Added RELATION is a GO:0071902 (positive regulation of protein serine/threonine kinase activity)
2012-10-29 Added RELATION is a GO:0043408 (regulation of MAPK cascade)
2012-01-29 Deleted RELATION part of GO:0043410 (positive regulation of MAPK cascade)
2012-01-22 Added RELATION positively regulates GO:0004709 (MAP kinase kinase kinase activity)
2011-05-12 Added RELATION part of GO:0043410 (positive regulation of MAPK cascade)
2011-05-12 Deleted RELATION part of GO:0000165 (MAPK cascade)
2008-04-01 Updated RELATION is a GO:0032147 (activation of protein kinase activity)
2008-04-01 Updated RELATION part of GO:0000165 (MAPK cascade)
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