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GO:0000159 protein phosphatase type 2A complex

Term Information

ID GO:0000159
Name protein phosphatase type 2A complex
Ontology Cellular Component
Definition A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
PMID:17245430
GONUTS GO:0000159 Wiki Page

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

Protein complexes

Database ID Name
IntAct pp2a_yeast-1 Serine/threonine-protein phosphatase PP2A variant 1
IntAct pp2a_yeast-2 Serine/threonine-protein phosphatase PP2A variant 2
IntAct pp2a_yeast-4 Serine/threonine-protein phosphatase PP2A variant 4
IntAct pp2a_yeast-3 Serine/threonine-protein phosphatase PP2A variant 3

Cross-references

Database ID
InterPro IPR000009
InterPro IPR002554

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000159:
Term has no children

Protein Annotation

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GO Identifier
GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0000159. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0000159 based on the entire annotation set Co-occurrence statistics for GO:0000159 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2009-12-10 Added DEFINITION A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
2009-12-10 Deleted DEFINITION A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
2009-12-06 Deleted DEFINITION A heterodimer with protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic and regulatory subunits.
2009-12-06 Added DEFINITION A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
2008-05-13 Added DEFINITION A heterodimer with protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic and regulatory subunits.
2008-05-12 Deleted DEFINITION A heterodimer with protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic and regulatory subunits.
2008-04-01 Updated RELATION is a GO:0044424 (intracellular part)
2008-04-01 Updated RELATION is a GO:0008287 (protein serine/threonine phosphatase complex)
2006-06-03 Updated DEFINITION A heterodimer with protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic and regulatory subunits.
2002-06-12 Updated TERM protein phosphatase type 2A complex
2002-02-06 Updated TERM protein phosphatase type 2A
2001-08-06 Added DEFINITION A protein serine/threonine phosphatase that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine.
2001-04-03 Updated TERM protein phosphatase type 2A
2001-03-30 Added TERM protein phosphatase type 2A

Term

Timestamp Action Category Detail
2002-06-12 Updated TERM protein phosphatase type 2A complex
2002-02-06 Updated TERM protein phosphatase type 2A
2001-04-03 Updated TERM protein phosphatase type 2A
2001-03-30 Added TERM protein phosphatase type 2A

Definition/synonyms

Timestamp Action Category Detail
2009-12-10 Added DEFINITION A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
2009-12-10 Deleted DEFINITION A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
2009-12-06 Deleted DEFINITION A heterodimer with protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic and regulatory subunits.
2009-12-06 Added DEFINITION A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
2008-05-13 Added DEFINITION A heterodimer with protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic and regulatory subunits.
2008-05-12 Deleted DEFINITION A heterodimer with protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic and regulatory subunits.
2006-06-03 Updated DEFINITION A heterodimer with protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic and regulatory subunits.
2001-08-06 Added DEFINITION A protein serine/threonine phosphatase that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0044424 (intracellular part)
2008-04-01 Updated RELATION is a GO:0008287 (protein serine/threonine phosphatase complex)
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